A5050683992- Venous Thromboembolism Diagnosis and Management
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Diagnosis and Treatment of Venous Diseases
- Vascular Procedures and Complications
- Renal and Vascular Pathologies
- Renal Transplantation Outcomes and Treatments
- Central Venous Catheters and Hemodialysis
- Angiogenesis and VEGF in Cancer
- Aortic Disease and Treatment Approaches
- Organ Donation and Transplantation
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Indian and Buddhist Studies
- Organ Transplantation Techniques and Outcomes
- Abdominal vascular conditions and treatments
- Chinese history and philosophy
- Infectious Aortic and Vascular Conditions
- Dermatologic Treatments and Research
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetic Foot Ulcer Assessment and Management
- Lymphatic System and Diseases
- Vascular anomalies and interventions
- Protease and Inhibitor Mechanisms
- Atrial Fibrillation Management and Outcomes
Seoul National University Bundang Hospital
2015-2024
Seoul National University
2013-2024
Seoul National University Hospital
2009-2023
Argonne National Laboratory
2020
Yeouido St. Mary's Hospital
2016
Catholic University of Korea
2016
Yale University
2003-2009
National University College
2009
New Generation University College
2009
CHA University
2009
β-aminoisobutyric acid (BAIBA) is produced in skeletal muscle during exercise and has beneficial effects on obesity-related metabolic disorders such as diabetes non-alcoholic fatty liver disease. Thus, it supposed to prevent high fat diet (HFD)-induced inflammation insulin resistance adipose tissue though anti-inflammatory obesity. Previous reports have also demonstrated strong of BAIBA.We used BAIBA treated fully differentiated 3T3T-L1 mouse adipocytes investigate the exogenous signaling...
Study Objectives: To investigate flow-mediated dilatation (FMD) and C-reactive protein (CRP) levels in patients with obstructive sleep apnea syndrome (OSAS) relation the severity of respiratory disturbances hypoxemia.Design: After subjects had completed nocturnal polysomnography, FMD was measured brachial artery, blood samples were obtained to determine serum CRP levels.Setting: Sleep laboratory Seoul National University Bundang Hospital.Patients: Ninety men: 22 normal controls, 28 mild...
To determine the 1-year survival rate, amputation-free rate and risk factors of amputation for patients with diabetic foot ulcers.One hundred seventy-three ulcers were included in our study. Mean patient age was 67.5 (range, 29 to 87, SD ±11.4) years. 74% male. Time from study entry time death evaluated separately as censored event times by Kaplan-Meier curves log-rank tests. A multivariate Cox proportional hazards regression analysis carried out determining amputation.The 96.5% (n=167),...
This study introduces Angio-Net, which integrates a high-throughput 3D cell culture device, large-scale image data generation, and deep learning-based virtual staining. The system demonstrated fast accurate quantitative analysis of complex angiogenesis.
The metabolic syndrome (MS) is a known risk factor for arterial thromboembolism. Preliminary reports have also suggested the association between MS and venous thromboembolism (VTE).In this case-control study, we investigated VTE in Korean patients. Patients with objectively diagnosed healthy control subjects underwent clinical assessment presence of according to National Cholesterol Education Adult Treatment Panel III criteria modified body mass index (WHO Asian Pacific Perspective, 2000)....
Coronavirus disease 2019 (COVID-19) has had a major impact on global communities and healthcare.Paxlovid (nirmatrelvir/ritonavir) is an oral drug for the treatment of COVID-19 that been approved by U.S. Food Drug Administration.In Korea, Paxlovid first-line patients who are >60 years old or using immunosuppressants, those >40 with chronic diseases such as obesity, diabetes, kidney disease, hypertension.One caveat potential risk interaction it strong cytochrome P450 (CYP) 3A P-glycoprotein...
This study aimed to investigate factors affecting length of hospital stay and mortality a specific group patients with infected diabetic foot ulcer who underwent surgical drainage without major amputation, which is frequently encountered by orthopedic surgeons. Data on stay, mortality, demographics, other medical information were collected for 79 consecutive (60 men, 19 women; mean age, 66.1 [SD, 12.3] yr) while retaining the heel between October 2003 May 2013. Multiple linear regression...
Abstract We have previously reported that cyclic strain results in rapid phosphorylation of p38 mitogen activated protein kinase (MAPKs). The aim this study was to examine the role phosphatase type 2A (PP2A) regulating MAPK activation bovine aortic endothelial cells exposed strain. In study, we demonstrate catalytic subunit PP2A is tyrosine phosphorylated by strain, resulting inhibition activity. Okadaic acid, an inhibitor at lower concentrations increased p‐38. Phospho‐p38 physically...
Secondary lymphedema is an intractable disease mainly caused by damage of the lymphatic system during surgery, yet studies are limited lack suitable animal models. The purpose this study was to create improved model secondary in hindlimbs rodents with sustained effects and able mimic human lymphedema. This achieved combining previously reported surgical methods radiation induce chronic Despite more radical destruction superficial deep vessels, surgery alone not enough sustain increased...
Recently non-Vitamin K antagonist oral anticoagulants (NOAC) is replacing warfarin for the treatment of deep vein thrombosis (DVT). However, role NOAC after thrombolysis acute iliofeomral DVT (IFDVT) not yet defined. This randomized clinical trial aimed to compare safety and efficacy rivaroxaban versus catheter directed an IFDVT. Patients with both iliac femoral (n = 72) were recruited either standard anticoagulation (enoxaparin warfarin, n 35) or 37) successful mechanical thrombectomy....
Safety and effectiveness of radiofrequency ablation for incompetent small saphenous vein is not established.To report midterm clinical ultrasonograhic results (RFA) (SSV) in terms recanalization sural neuritis.We examined 39 patients (46 limbs) who had been using a duplex scan more than 1 year after RFA SSV. Postoperative results, risk factors SSV recanalization, neuritis were analyzed.CEAP score CIVIQ2 improved significantly all (CEAP: 2.45 to 1.43 (p = .03); CIVIQ2: 25.34 13.21 .01)....
We evaluated whether LD can detect alterations in skin microcirculatory flow type II diabetic neuropathy patients and determined which parameters were most predictive.A prospective analysis was performed for three groups with presumed varying degrees of microvascular dysfunction: diabetics (DMN, n = 20), without microangiopathic complications (DM, healthy controls (n 16). under strictly controlled protocols provocation, consisting vasoconstrictive (valsalva, postural) vasodilative tests...