A5101905450- Microbial Community Ecology and Physiology
- Mycorrhizal Fungi and Plant Interactions
- Epigenetics and DNA Methylation
- Gut microbiota and health
- Soil Carbon and Nitrogen Dynamics
- Forest Ecology and Biodiversity Studies
- Polar Research and Ecology
- Wnt/β-catenin signaling in development and cancer
- Fungal Biology and Applications
- Autophagy in Disease and Therapy
- Psychological Well-being and Life Satisfaction
- DNA Repair Mechanisms
- Cancer Genomics and Diagnostics
- Advancements in Battery Materials
- Microtubule and mitosis dynamics
- Cancer Research and Treatments
- Ideological and Political Education
- RNA modifications and cancer
- Cancer, Hypoxia, and Metabolism
- Housing Market and Economics
- Cancer-related gene regulation
- CRISPR and Genetic Engineering
- Lichen and fungal ecology
- COVID-19 and Mental Health
- Housing, Finance, and Neoliberalism
Inner Mongolia University
2020-2025
Qingdao University of Science and Technology
2025
General Motors (Poland)
2025
The University of Texas at Austin
2022-2024
Zhejiang University of Technology
2023-2024
ORCID
2024
Peking University
2012-2022
King University
2021
Peking University First Hospital
2021
Weatherford College
2021
Soil microbial communities were investigated under the volcanic extreme environment. bacterial networks exhibited higher stability than fungal networks. Holocene granite had a more complex network basalt. pH and total protein key drivers of stability. Volcanic activity is great significance not only because it powerful strength shaping global landscape but also common cause geological ecological disturbances [1, 2]. The Wulanhada volcanoes in Inner Mongolia Northern China erupted during...
Abstract Purpose: NAT10 (N-acetyltransferase 10) is a nucleolar protein, but may show subcellular redistribution in colorectal carcinoma. In this study, we evaluated membranous staining of carcinoma and its clinical implications, explored the mechanism regulation redistribution. Experimental Design: The expression NAT10, β-catenin, E-cadherin, GSK-3β were by immunohistochemistry 222 cases Regulation influence on cell motility analyzed with inhibitors GSK-3β, transfection wild-type or...
Objective Familial adenomatous polyposis (FAP) is characterised by the development of hundreds to thousands adenomas at different evolutionary stages in colon and rectum that will inevitably progress adenocarcinomas if left untreated. Here, we investigated genetic alterations transcriptomic transitions from precancerous adenoma carcinoma. Design Whole-exome sequencing, whole-genome sequencing single-cell RNA were performed on matched adjacent normal tissues, multiregionally sampled...
Summary Root‐associated microbiomes play significant roles in plant productivity, health and ecological services. However, our current understanding of the microbial assemblages rhizosphere endosphere herbage is still limited. To gain insights into these assemblages, Illumina MiSeq high‐throughput sequencing was performed to investigate characteristics communities an herbage, Leymus chinensis . Hierarchical clustering analysis principal coordinate (PCoA) results showed that samples were...
The formation of micronuclei (MN) is prevalent in human cancer cells and its role activating the senescence-associated secretory phenotype (SASP) machinery has been identified recently. However, MN regulation SASP signaling still needs to define practical cancers. Here, we reported that colorectal expression NAT10 (N-acetyltransferase 10) could mediate through DNA replication NAT10-positive activate by binding cGAS. chemical inhibition Remodelin or genomic depletion markedly reduce...
Cancer suppression through the inhibition of N-acetyltransferase 10 (NAT10) by its specific inhibitor Remodelin has been demonstrated in a variety human cancers. Here, we report inhibitory effects on prostate cancer (PCa) cells and possible associated mechanisms. The cell lines VCaP, LNCaP, PC3, DU145 were used. vitro proliferation, migration, invasion measured proliferation assay, colony formation, wound healing, Transwell assays, respectively. In vivo tumor growth was analyzed...
Arid desert regions are among the harshest ecological environments on Earth. Halophytes, with their unique physiological characteristics and adaptability, have become dominant vegetation in these areas. Currently, research halophytes this region is relatively limited, particularly concerning studies related to root endophytic fungi, which been rarely reported on. Therefore, investigating diversity composition of fungi crucial for maintaining balance such an arid environment. This study...
Abstract Improving the initial Coulombic efficiency (ICE) of silicon anodes in lithium-ion batteries is a key challenge for enhancing their performance. Traditional prelithiation methods, such as using lithium naphthalenide (Li-Naph), are limited by low lithiation potential crystalline silicon, making them less effective commercial applications. This study demonstrates that amorphous anodes, with higher potential, can be effectively prelithiated Li-Naph. process also forms robust solid...
Single atom catalysts embracing metal‐nitrogen (MNx) moieties show promising performance for oxygen reduction reaction (ORR). The modification on spatially confined microenvironments, which won copious attention with respect to achieving efficient catalysts, are auspicious but yet be inspected MNx from modulating the energetics and kinetics of ORR. Here, Fe single atoms (SAs) immobilized in microporous hard carbon (Fe‐SAs/MPC), structure crumpled graphene sheets serves microenvironment...
Single atom catalysts embracing metal‐nitrogen (MNx) moieties show promising performance for oxygen reduction reaction (ORR). The modification on spatially confined microenvironments, which won copious attention with respect to achieving efficient catalysts, are auspicious but yet be inspected MNx from modulating the energetics and kinetics of ORR. Here, Fe single atoms (SAs) immobilized in microporous hard carbon (Fe‐SAs/MPC), structure crumpled graphene sheets serves microenvironment...
Low density lipoprotein (LDL) receptor-related protein-6 (LRP6) is an important co-receptor of Wnt pathway, which plays a predominant role in development and progression colorectal cancer. Recently, dysregulation LRP6 has proved to be involved the cancers, but its biological clinical significance cancer remain unclear. In present study, we revealed that phosphorylation was aberrantly upregulated carcinoma correlating with TNM or Dukes staging worse prognosis. addition, phosphorylated...
Abstract Nursing students are the main force of future nursing development, and their hope death anxiety important aspects coping styles clinical practice. The present study examined relationships between hope, simplified style scores during outbreak COVID-19. Between February April 2020, a cross-sectional descriptive was performed using Sojump online survey, 870 completed herth (HH), scale (DAS) questionnaire. data were analyzed t -tests, one-way analysis variance (ANOVA), multiple linear...
Concerning China's growth in biotechnology, the research on biotech start-ups China yields significant implications. However, studies have not given enough attention to hospitals, which are critical players industry. Because of hospital-centric healthcare system, public tertiary hospitals important partners for start-ups. This study investigates geographical relationship between and Chinese cities. The findings suggest evidence collocation, reflects their alliances. thereby contributes...
Hypoxia-inducible factors (HIFs) are key mediators expressed under hypoxic condition and involved in many kinds of disease such as cancer abnormal angiogenesis. Thus, development their inhibitor has been extensively explored. Here, we describe a finding that Remodelin, specific NAT10, could also inhibit the expression HIFs. The presence Remodelin suppress elevated level HIF-1α protein its nuclear translocation induced by either treatment cobalt chloride (CoCl2) or hypoxia dose time-dependent...
Arbuscular mycorrhizal fungi (AMF) have been reported to a wide distribution in terrestrial ecosystems and play vital role ecosystem functioning symbiosis with Stipa grasses. However, exactly how AMF communities the rhizosphere change are distributed along different population substituted their relationships remain unclear. Here, changes of associations between hosts dynamic differences glomalin-related soil protein (GRSP) seven species spatial substitution characteristics arid semiarid...