- Venous Thromboembolism Diagnosis and Management
- Mosquito-borne diseases and control
- Acute Myocardial Infarction Research
- Reproductive tract infections research
- Global Maternal and Child Health
- Atrial Fibrillation Management and Outcomes
- Adolescent Sexual and Reproductive Health
- Reproductive Health and Contraception
- Viral Infections and Vectors
- Acute Ischemic Stroke Management
- Clinical practice guidelines implementation
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Hemoglobinopathies and Related Disorders
- Diabetes and associated disorders
- Erythrocyte Function and Pathophysiology
- Blood Coagulation and Thrombosis Mechanisms
- Chronic Lymphocytic Leukemia Research
- Central Venous Catheters and Hemodialysis
- Hepatitis C virus research
- Syphilis Diagnosis and Treatment
- Chemotherapy-induced cardiotoxicity and mitigation
- Heparin-Induced Thrombocytopenia and Thrombosis
- Travel-related health issues
- Paraoxonase enzyme and polymorphisms
Office of Public Health Genomics
2024
Centers for Disease Control and Prevention
2016-2024
National Center on Birth Defects and Developmental Disabilities
2018-2024
National Center for Chronic Disease Prevention and Health Promotion
2016
Tulane University
2013-2015
Southern Illinois University School of Medicine
2006-2008
In collaboration with state, tribal, local, and territorial health departments, CDC established the U.S. Zika Pregnancy Registry (USZPR) in early 2016 to monitor pregnant women laboratory evidence of possible recent virus infection their infants.This report includes an analysis completed pregnancies (which include live births pregnancy losses, regardless gestational age) 50 states District Columbia (DC) reported USZPR from January 15 December 27, 2016. Birth defects potentially associated...
OBJECTIVE: Zika virus infection during pregnancy is a cause of microcephaly and other fetal brain abnormalities. Reports indicate that the duration detectable viral RNA in serum after symptom onset brief. In recent case report involving severely affected fetus, was detected maternal 10 weeks onset, longer than detection previously reported. This summarizes clinical laboratory characteristics pregnant women with prolonged were reported to U.S. Pregnancy Registry. METHODS: Data obtained from...
Zika virus infection can occur as a result of mosquitoborne or sexual transmission the virus. Infection during pregnancy is cause fetal brain abnormalities and other serious birth defects (1,2). CDC has updated interim guidance for men with possible exposure who 1) are planning to conceive their partner, 2) want prevent at any time (3). now recommends that partner wait least 3 months after symptom onset (if symptomatic) last asymptomatic) before engaging in unprotected sex. also couples not...
Abstract Background Three months after the first reported cases, COVID-19 had spread to nearly 90% of World Health Organization (WHO) member states and only 24 countries not cases as 30 March 2020. This analysis aimed 1) assess characteristics, capability detect monitor COVID-19, disease control measures in these countries, 2) understand potential factors for delayed introduction, 3) identify gaps opportunities outbreak preparedness, particularly low middle-income (LMICs). We collected...
BackgroundPopulation‐based data about cerebral venous sinus thrombosis (CVST) are limited.ObjectivesTo investigate the epidemiology of CVST in United States.Patients/MethodsThree administrative systems were analyzed: 2018 Healthcare Cost and Utilization Project National Inpatient Sample (NIS) 2019 IBM MarketScan Commercial Medicare Supplemental Claims Database, Multi‐state Medicaid Database. CVST, thrombocytopenia, numerous comorbidities identified using International Classification...
Objectives: In response to an expressed need for more focused measurement of preconception health (PCH), we identify a condensed set PCH indicators state and national surveillance. Methods: We used systematic process evaluate, prioritize, select 10 that maternal child programs can use For each indicator, assessed prevalence, whether it was addressed by professional recommendations, Healthy People 2020 objectives, or Centers Disease Control Prevention winnable battles, simplicity, data...
Venous thromboembolism (VTE) is a leading cause of preventable mortality among hospitalized patients, but appropriate risk assessment and thromboprophylaxis remain underutilized or misapplied.We conducted an electronic survey US health care providers to explore attitudes, practices, barriers related in adult patients at discharge.A total 607 respondents completed the survey: 63.1% reported working academic hospital, 70.7% identified as physicians, hospital medicine was most frequent...
Abstract Venous thromboembolism (VTE) is the leading cause of preventable death in hospitalized patients. Artificial intelligence (AI) and machine learning (ML) can support guidelines recommending an individualized approach to risk assessment prophylaxis. We conducted electronic surveys asking clinician healthcare informaticians about their perspectives on AI/ML for VTE prevention management. Of 101 respondents informatician survey, most were 40 years or older, male, clinicians data...
Summary. Many patients with chronic hepatitis C (HCV) infection undergoing treatment pegylated interferon‐alpha (PEG‐IFN‐alpha) and ribavirin develop neutropenia requiring dose reduction or granulocyte colony‐stimulating factor (G‐CSF) supplement. We analysed the database of who completed for HCV between 2003 2006. Patients absolute neutrophil counts below 1000 cells/ μ L were initiated on G‐CSF (G‐CSF group) while a matching group received anti‐HCV without developing used as control...
Women coinfected with human immunodeficiency virus (HIV) and Trichomonas vaginalis who are treated 2 grams metronidazole (MTZ) more likely to have persistent infections if they receiving antiretroviral therapy compared similar women multidose MTZ. Objective. Among positive (HIV+), both prevalent (TV) common. TV has been shown increase vaginal shedding of HIV, which may influence HIV sexual perinatal transmission, making prevention important. In 1 cohort HIV+ in Kenya, (ART) use, mostly...
Background: Limited surveillance of preconception care (PCC) impedes states' ability to monitor access and provision quality PCC. In response, we describe PCC indicators the evaluation process used identify a set for state use. Materials Methods: The Surveillance Research Workgroup Clinical National Preconception Health Care Initiative systematic identify, evaluate, prioritize from nationwide public health systems that Maternal Child (MCH) programs can use state-level using Pregnancy Risk...
We studied in vitro production of interferon-gamma and expression receptors (R1 R2) by the peripheral blood mononuclear cells 24 HIV-1-infected patients 12 healthy volunteers. Interferon-gamma was lower compared with volunteers (p < 0.05), it further declined CD4+ T-cell counts. In contrast, R1 T lymphocytes higher HIV-infected than (25% versus 10%, p 0.05). group, increased a decline count (r = -0.64, 0.001). R2 directly correlated When stimulated heat-killed Mycobacterium avium complex...
Background: Venous thromboembolism (VTE) is a preventable, common vascular disease that has been estimated to affect up 900,000 people per year. It associated with risk factors such as recent surgery, cancer, and hospitalization. VTE surveillance for patient management safety can be improved via natural language processing (NLP). NLP tools have the ability access electronic medical records, identify patients meet case definition, subsequently enter relevant information into database hospital review.
Venous thromboembolism (VTE) affects approximately 1-2 individuals per 1000 annually and is associated with an increased risk for pulmonary hypertension, postthrombotic syndrome, recurrent VTE.
As the prevalence of chronic conditions among women reproductive age continues to rise, studies assessing intersection disease and women's health status are increasingly needed. However, many data systems collect only limited information on health, thereby hampering appraisal risk protective factors across life span. One way expand study with minimal investment in time resources is integrate questions into existing surveillance systems. In 2013, previously validated self-reported history,...