A5044636000- Adolescent Sexual and Reproductive Health
- Reproductive tract infections research
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Reproductive Health and Contraception
- Syphilis Diagnosis and Treatment
- Sex work and related issues
- Cervical Cancer and HPV Research
- Homelessness and Social Issues
- COVID-19 Clinical Research Studies
- Urinary Tract Infections Management
- HIV Research and Treatment
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Hepatitis C virus research
- COVID-19 epidemiological studies
- SARS-CoV-2 detection and testing
- Global Maternal and Child Health
- Parasitic Infections and Diagnostics
- Herpesvirus Infections and Treatments
- HIV-related health complications and treatments
- Pneumocystis jirovecii pneumonia detection and treatment
- Long-Term Effects of COVID-19
- Genital Health and Disease
- Tuberculosis Research and Epidemiology
Tulane University
2015-2024
University of Alabama at Birmingham
2016-2023
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2023
National Institute of Allergy and Infectious Diseases
2021-2023
University of New Orleans
2023
Hyperion Technologies (Canada)
2023
Lupin Pharmaceuticals (United States)
2023
Lupin Pharmaceuticals (India)
2023
Abbott (United Kingdom)
2023
St. Vincent's Birmingham
2023
<h3>Importance</h3> The SARS-CoV-2 viral trajectory has not been well characterized in incident infections. These data are needed to inform natural history, prevention practices, and therapeutic development. <h3>Objective</h3> To characterize early RNA load (hereafter referred as load) individuals with infections association COVID-19 symptom onset severity. <h3>Design, Setting, Participants</h3> This prospective cohort study was a secondary analysis of remotely conducted that enrolled 829...
Collection of sensitive data with the use video-enhanced, computer-assisted, self-administered interviews (V-CASI) has potential to reduce interview bias and improve validity study. The purpose this study was compare responses questions elicited by V-CASI face-to-face (FTFI) methods. Women attending a New Orleans, Louisiana, public family planning or sexually transmitted disease clinic from July 1995 1996, diagnosed Chlamydia trachomatis infection responded eight close-ended behavioral (four...
In Brief Background Repeated infection with Chlamydia trachomatis increases the risk for serious sequelae: pelvic inflammatory disease, ectopic pregnancy, infertility, and chronic pain. A substantial proportion of women treated C are reinfected by an untreated male sex partner in first several months after treatment. Effective strategies to ensure treatment needed. Goal The goal study was determine whether repeated infections can be reduced giving doses azithromycin deliver partners. Study...
Objectives To describe the patterns and correlates of discontinuation initial highly active antiretroviral therapy (HAART) regimen in an urban, outpatient cohort antiretroviral-naive patients. Design Retrospective 345 randomly selected patients who initiated HAART on 6 regimens between January 1997 May 2001 New Orleans, LA. Methods An investigator reviewed medical records to collect information concurrent medications, symptoms/diagnoses, staging indicators, reasons for discontinuation....
Vaginal HIV-1 shedding has been associated with Trichomonas vaginalis (TV) infection and could play a role in HIV transmission. The purpose of the study was to examine if effective TV treatment reduces presence vaginal RNA.TV+ women attending an outpatient clinic New Orleans, LA, who resolved (n = 58) TV-negative controls 92), matched on antiretroviral therapy (ART) were examined interviewed at baseline, 1, 3 months. status tested by culture amount cell free RNA fluids determined Amplicor...
Effective prevention against coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome 2 (SARS-CoV-2), is currently limited to nonpharmaceutical strategies. Laboratory and observational data suggested that hydroxychloroquine had biological activity SARS-CoV-2, potentially permitting its use for prevention.
Treatment options for outpatients with COVID-19 could reduce morbidity and prevent SARS-CoV-2 transmission.In this randomized, double-blind, three-arm (1:1:1) placebo-equivalent controlled trial conducted remotely throughout the United States, adult laboratory-confirmed infection were recruited. Participants randomly assigned to receive hydroxychloroquine (HCQ) (400 mg BID x1day, followed by 200 x9days) or without azithromycin (AZ) (500 mg, then 250 daily x4days) (ascorbic acid folic (AZ)),...
Trichomonas vaginalis is likely the most prevalent nonviral sexually transmitted infection, affecting an estimated 3.7 million women and men in United States. Health disparities are prominent epidemiology of trichomoniasis, as African Americans >4 times more to be infected than persons other races. Since publication 2015 Centers for Disease Control Prevention diseases treatment guidelines, additional data have bolstered importance T. infection sequelae women, including increased risk human...
Background Sequelae of genital Chlamydia trachomatis infection in women are more strongly linked to repeat infections than initial ones, and persistent or subsequent foster continued transmission. Objective To identify factors associated with recurrent chlamydial young that might influence prevention strategies. Methods Teenage adult uncomplicated C attending reproductive health, sexually transmitted disease, adolescent medicine clinics five US cities were recruited a cohort study....
Traditional partner referral for sexually transmitted diseases (STDs) is ineffective at assuring that partners are treated. Alternative methods needed. We sought to determine whether patient-delivered treatment (PDPT) better than 2 different of in providing antibiotic sex men with urethritis and reducing recurrence Chlamydia trachomatis Neisseria gonorrhoeae.Men who received a diagnosis public STD clinic New Orleans, Louisiana, during the period December 2001 through March 2004 were randomly...
The study tested the model of adaptation after trauma by Benight and Bandura (2004) indicating that posttraumatic recovery may be predicted directly coping self-efficacy (CSE) indirectly social support. These relations were investigated in context growth (PTG) among Hurricane Katrina survivors living with HIV. Additionally, it was hypothesized individuals more intensive Posttraumatic Stress Disorder (PTSD) symptoms, those strong CSE would experience strongest PTG. Cross-sectional data...
<h3>Importance</h3> Racial and ethnic diversity among study participants is associated with improved generalizability of clinical trial results may address inequities in evidence that informs public health strategies. Novel strategies are needed for equitable access recruitment diverse populations. <h3>Objective</h3> To investigate demographic geographical location data 2 remote COVID-19 trials online compare those a contemporaneous clinic-based study. <h3>Design, Setting, Participants</h3>...
Background: Chemsex is the intentional use of drugs to enhance sexual activity. drug among men who have sex with (MSM) associated behaviors that increase sexually transmitted infection (STI) risks and adverse mental health outcomes. However, published data are largely based on MSM recruited from STI clinics. There limited about chemsex national samples in United States. Using American Men's Internet Survey (AMIS), we assessed prevalence correlates active Methods: We used 2017 2020 AMIS...
The goal of this study was to investigate clinical outcomes and survival probabilities among persons coinfected with human immunodeficiency virus (HIV) T lymphotropic viruses types 1 2 (HTLV-I/II). A nonconcurrent cohort 1033 HIV-infected individuals also conducted. Sixty-two patients were HTLV-I, 141 HTLV-II. HTLV-I/II coinfection highly associated African-American race/ethnicity, age >36 years, higher CD4(+) cell count at baseline over time, history injection drug use. Coinfected more...
Abstract Prevalence of multiple human papillomavirus (HPV) infections, involvement specific HPV phylogenetic clades in and clustering patterns infections at the clade level were assessed 854 HIV (−) 275 (+) women cross-sectionally. Reverse line blot assay was used to detect 27 genotypes. Involvement coinfections using clade/genotype as unit analyses. Expected frequencies assuming independence for all possible combinations two-genotype derived a multinomial expansion comparisons observed...
The purpose of the study was to examine whether early repeated infections due Trichomonas vaginalis among human immunuodeficiency virus (HIV)-positive and HIV-negative women are reinfections, new infections, or cases treatment failure.
Objective: To determine if the metronidazole (MTZ) 2-gm single dose (recommended) is as effective 7-day 500 mg twice a day (alternative) for treatment of Trichomonas vaginalis (TV) among HIV+ women. Methods: Phase IV randomized clinical trial; women with culture confirmed TV were to arm: MTZ or dose. All given doses deliver their sex partners. Women recultured at test-of-cure (TOC) visit occurring 6-12 days after completion. TV-negative TOC again 3-month visit. Repeat infection rates...