A5043235494- Cytokine Signaling Pathways and Interactions
- Cancer Mechanisms and Therapy
- Palliative Care and End-of-Life Issues
- HIV/AIDS Research and Interventions
- Anesthesia and Pain Management
- SARS-CoV-2 detection and testing
- Biosensors and Analytical Detection
- Mycobacterium research and diagnosis
- Cardiac, Anesthesia and Surgical Outcomes
- Immune Cell Function and Interaction
- HIV/AIDS drug development and treatment
- HIV Research and Treatment
- Adolescent Sexual and Reproductive Health
- Cancer Immunotherapy and Biomarkers
- Streptococcal Infections and Treatments
- Cardiovascular Issues in Pregnancy
- Financial Literacy, Pension, Retirement Analysis
- Global Health and Surgery
- HIV/AIDS Impact and Responses
- Advanced biosensing and bioanalysis techniques
- Health Systems, Economic Evaluations, Quality of Life
- Economic and Financial Impacts of Cancer
- Bacterial Identification and Susceptibility Testing
- Pneumocystis jirovecii pneumonia detection and treatment
- Pain Management and Opioid Use
Baylor University
2021-2025
Aquatic Systems (United States)
2022-2025
Olivia Newton-John Cancer Wellness & Research Centre
2023
La Trobe University
2023
Adelphi Group (United Kingdom)
2023
American Cancer Society
2010-2022
University of Michigan
2022
Hindustan Aeronautics Limited (India)
2021
Massey University
2021
Burton Hospitals NHS Foundation Trust
2021
Objectives To describe the patterns and correlates of discontinuation initial highly active antiretroviral therapy (HAART) regimen in an urban, outpatient cohort antiretroviral-naive patients. Design Retrospective 345 randomly selected patients who initiated HAART on 6 regimens between January 1997 May 2001 New Orleans, LA. Methods An investigator reviewed medical records to collect information concurrent medications, symptoms/diagnoses, staging indicators, reasons for discontinuation....
To examine the association of anemia with mortality and disease progression among a cohort women HIV in Dar es Salaam, Tanzania.Time to all-cause death, AIDS-related 50% decrease CD4 cell count 1078 HIV-positive pregnant enrolled clinical trial vitamin supplementation from 1995-2003.Adjusted models showed that was associated an increased risk (relative hazard [RH]: 2.06, 95% CI: 1.52 2.79 for moderate RH: 3.19, 2.23 4.56 severe anemia) (RH: 2.21, 1.53 3.19 3.47, 2.25 5.33 anemia),...
Due to its increasing affordability and efforts understand transcriptional responses of organisms biotic abiotic stimuli, transcriptomics has become an important tool with significant impact on toxicological investigations hazard risk assessments, especially during development application new approach methodologies (NAMs). Data generated using transcriptomic have directly informed adverse outcome pathway frameworks, chemical biological read across, aided in the identification points...
A study of HIV-positive individuals in New Orleans, Louisiana, found that the majority patients disclosed to their main partners and family members, but less than one fourth any casual sex partner. Older age lower CD4 cell counts were associated with disclosure.The goal was describe patterns HIV serostatus disclosure among a diverse sample at an outpatient clinic Louisiana.A convenience HIV-seropositive provided information about seropositivity, demographics, date diagnosis, count, mode...
ABSTRACT A retrospective analysis of susceptibility data on 542 blood isolates the Bacteroides fragilis group tested from 1987 to 1999 by same NCCLS-recommended broth microdilution method throughout is presented. Metronidazole, β-lactam-β-lactamase inhibitor combinations, carbapenems, and trovafloxacin were most active agents (susceptibility ≥93%). Among cephalosporin-cephamycins, order activity was cefoxitin > ceftizoxime cefotetan = cefotaxime cefmetazole ceftriaxone. All resistant...
In Brief Background: Prevalence of human papillomavirus (HPV)–associated oral condylomas has reportedly increased in HIV-infected individuals since the introduction highly active antiretroviral therapy (HAART). The relationships between HIV regimen, overall health, and subclinical HPV have not been examined. Goal: To determine genotype prevalence impact HAART health HIV+ population. Study: An L1 consensus-primer polymerase chain reaction linear array assay were used to examine 27 genotypes...
Uncomplicated urinary tract infections (uUTIs/acute cystitis) are among the most common in women worldwide. There differences uUTI treatment guidelines between countries and understanding needs of physicians diverse healthcare systems is important for developing new treatments. We performed a survey United States (US) Germany to understand their perceptions of, management approaches uUTI.
The Policy Forum allows health
Background: Middle and low-income countries have scaled up HIV treatment in the past 5 years. To maintain this effort, information regarding amounts types of drugs is needed. Shortages or overstock active pharmaceutical ingredients make scale-up efforts more difficult costly. inform global planning implementation, we estimate volume current future demand for first second-line antiretroviral drugs. Methods: Using regression analysis documented assumptions, estimated number individuals...
Wastewater-based epidemiology (WBE) provides an early warning and trend analysis approach for determining the presence of COVID-19 in a community complements clinical testing assessing population level, even as viral loads fluctuate. Here, we evaluate combinations two wastewater concentration methods (i.e., ultrafiltration composite supernatant-solid), four pre-RNA extraction modifications, three nucleic acid kits using different sampling locations. These consisted quarantine facility...
ABSTRACT A comparison of antimicrobial susceptibility data species the Bacteroides fragilis group for 1989-1990 and 1998-1999 studies showed statistically significant increases or decreases in vitro activity. Overall resistance were noted ampicillin-sulbactam clindamycin, while ertapenem cefoxitin. Susceptibilities to piperacillin-tazobactam, imipenem, meropenem, trovafloxacin remained virtually same two studies. Importantly, a change rates isolation various B. comprised 58% isolates 1989...
Objectives: To examine whether wasting during pregnancy, as measured by weight loss and low gain, is associated with increased mother-to-child transmission (MTCT) of HIV-1. Methods: This was a cohort study in Dar es Salaam, Tanzania, among 957 HIV-1-infected pregnant women. Weight at the first prenatal visit every month thereafter until delivery. defined weekly rate gain ≤0 >0 ≤166 g/wk. The incidences presumptive intrauterine (HIV status birth) intrapartum early breast-feeding 6 weeks) were...
An accurate forecast of global demand is essential to stabilize the market for artemisinin-based combination therapy (ACT) and ensure access high-quality, life-saving medications at lowest sustainable prices by avoiding underproduction excessive overproduction, each which can have negative consequences availability affordable drugs. A robust requires an understanding resources available support procurement these relatively expensive antimalarials, in particular from Global Fund, present...
Mathematical modeling has been applied to a range of policy-level decisions on resource allocation for HIV care and treatment. We describe the application classic operations research (OR) techniques address logistical management challenges in treatment scale-up activities resource-limited countries.We review categorize several major operational problems encountered over last decade global antiretroviral people with AIDS. While there are unique features that pose significant effective service...
In Brief Background Chlamydia trachomatis– infected female teenagers with older partners may be less likely to discuss the infection their partner(s) and use condoms therefore more get reinfected. Goal To determine if C trachomatis–infected were reinfected than those same-aged partners. Study Design Females aged 14 years 18 who had uncomplicated chlamydial infection, nonpregnant, attended clinics in five United States cities from June 1995 May 1997, completed treatment, resumed sexual...
To determine the prevalence trends of HIV-1 infection among pregnant women seen between 1995 and 2003 at public antenatal clinics (ANC) in city Dar es Salaam.Cross-sectional studies selected who were offered HIV testing as part research service programmes to prevent vertical transmission improve pregnancy outcomes.Consenting gave blood for antibody using a sequential ELISA protocol. Sociodemographic information was collected structured interviews.In total, 62% attending informed consent...
Objective: To quantify the burden of work-relevant persistent musculoskeletal (MSK) pain to a large UK employer. Methods: A retrospective, longitudinal, analytical cohort study using linked Rolls-Royce data systems. Cases were employees with MSK-related referral occupational health; controls age-, sex-, and job role-matched without such referral. Outcomes compared during 12 months’ follow-up. Results: Overall, 2382 matched case–control pairs identified (mean age: 46 y; 82% male). took 39,200...