A5091584657- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Moyamoya disease diagnosis and treatment
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Neurological Complications and Syndromes
- Neurosurgical Procedures and Complications
- Pancreatic and Hepatic Oncology Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Meningioma and schwannoma management
- Aortic Disease and Treatment Approaches
- Neuroendocrine Tumor Research Advances
- Head and Neck Surgical Oncology
- Advanced MRI Techniques and Applications
- Cerebrovascular and genetic disorders
- Cardiac Structural Anomalies and Repair
- Venous Thromboembolism Diagnosis and Management
- Coronary Interventions and Diagnostics
- Urinary and Genital Oncology Studies
- Sarcoma Diagnosis and Treatment
- Congenital Diaphragmatic Hernia Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Acute Lymphoblastic Leukemia research
- Cardiovascular Function and Risk Factors
The University of Tokyo
2011-2025
Kyowa Kirin (Japan)
2002-2024
University of Tokyo Hospital
2014-2024
Red Cross Hospital
2024
Showa University Northern Yokohama Hospital
2022
NTT Medical Center
2017-2018
Tokyo Metropolitan Tama Medical Center
2017-2018
St. Marianna University School of Medicine
2010-2016
Dokkyo Medical University
2011-2015
Showa General Hospital
2013-2015
Image-based computational fluid dynamics (CFD) is widely used to predict intracranial aneurysm wall shear stress (WSS), particularly with the goal of improving rupture risk assessment. Nevertheless, concern has been expressed over variability predicted WSS and inconsistent associations rupture. Previous challenges, studies from individual groups, have focused on aspects image-based CFD pipeline. The aim this Challenge was quantify total whole 3D rotational angiography image volumes five...
A method to produce coke in 'lump' form with high strength and reactivity through the addition of a catalyst was investigated order improve blast furnace reaction efficiency. The Ca compounds coal before carbonization found considerably increase at low temperature range thermal reserve zone furnace. Furthermore it proved that strong, highly reactive could be produced by adding Ca-rich non-caking adjusting blend composition. Based on this fundamental study, successfully ovens commercial...
The proportion of certain Bacteroidota species decreased in patients with ulcerative colitis, and the recovery is associated efficacy fecal microbiota transplantation therapy. We hypothesized that may advance colitis treatment. Accordingly, we aimed to evaluate anti-inflammatory effects strains isolated from donors.
SUMMARY Although triggering by infectious agents and abnormal immune responses may play some role in the pathogenesis of juvenile dermatomyositis syndrome (JDMS), precise mechanism muscle destruction vascular damage is largely unknown. In this study, we tried to elucidate cytotoxic T cells two patients with JDMS, who were diagnosed based on characteristic symptoms, laboratory data, MRI findings electromyographic patterns. Peripheral blood cell phenotypes determined flow cytometry, using mAbs...
Background Although perfusion imaging plays a key role in the management of steno‐occlusive diseases, clinical usefulness arterial spin labeling (ASL) is limited by technical issues. Purpose To examine effect transit time (ATT) prolongation on cerebral blood flow (CBF) measurement accuracy and identify best CBF protocol for diseases. Study Type Prospective. Population Moyamoya ( n = 10) atherosclerotic diseases 8). Field Strength/Sequence A 3.0T/3DT 1 ‐weighted ASL. Assessment...
Robust postoperative bypass development is a characteristic of moyamoya disease (MMD); however, genetic factors mediating this phenomenon remain incompletely understood. Therefore, we aimed to elucidate the relationship between donor artery and variants. We retrospectively enrolled 63 patients (79 hemispheres) who underwent combined revascularization surgery. Postoperative superficial temporal (STA), middle meningeal artery, deep (DTA) was assessed using caliber-change ratio determined from...
Abstract Three-dimensional vessel model reconstruction from patient-specific magnetic resonance angiography (MRA) images often requires some manual maneuvers. This study aimed to establish the deep learning (DL)-based method for reconstruction. Time of flight MRA 40 patients with internal carotid artery aneurysms was prepared, and three-dimensional models were constructed using threshold region-growing method. Using those datasets, supervised 2D U-net performed reconstruct 3D models. The...
We identify possible differences in the cytokine/chemokine profiles cerebrospinal fluid (CSF) from children with encephalopathy and febrile seizure. Interleukin (IL)-1beta, 2, 4, 5, 6, 7, 8, 10, 12, 13, 17, interferon-gamma, tumour necrosis factor-alpha, granulocyte colony-stimulating factor, monocyte chemoattractant protein-1 macrophage inflammatory protein-1beta were measured simultaneously CSF supernatants (n = 8), seizure 16) fever without neurological complications 8). IL-8 was...
Background Noninvasive cerebral blood flow (CBF) monitoring using arterial spin labeling (ASL) magnetic resonance imaging is useful for managing large artery steno‐occlusive diseases. However, knowledge about its measurement characteristics in comparison with reference standard perfusion limited. Purpose To evaluate a longitudinal manner patients disease ASL and compare single‐photon emission computed tomography (SPECT). Study Type Prospective. Population Moyamoya ( n = 10, eight females)...
Introduction Endovascular treatment for acute ischemic stroke with large-vessel occlusion (ALVO) has established benefits, and rapid is vital mechanical thrombectomy in ALVO. Time from onset of to groin puncture (OTP) a practical useful clinical marker, OTP should be shortened obtain the maximum benefit thrombectomy. Objective The aim present study was assess impact early anterior circulation within three hours after symptom evaluate role determining outcomes endovascular therapy. Methods...
It is debated whether the efficacy and long-term safety of gamma knife radiosurgery (GKRS) for arteriovenous malformations (AVMs) differs between adult pediatric patients. We aimed to clarify outcomes GKRS in patients how they compare those collected data 736 consecutive with AVMs treated 1990 2014 divided into (age < 20 years, n = 144) ≥ 592) cohorts. The mean follow-up period cohort was 130 months. Compared patients, were significantly more likely have a history hemorrhage (P 0.001)....
Abstract BACKGROUND High-definition vascular imaging is desirable for treatment planning in Gamma Knife radiosurgery (GKRS; Elekta AB) brain arteriovenous malformations (BAVMs). Currently, rotational angiography (RA) provides the clearest 3-dimensional visualization of niduses with high spatial resolution; however, its efficacy GKRS has not been clarified. At our institution, RA integrated into (RA-GKRS) better and outcomes since 2015. OBJECTIVE To evaluate RA-GKRS BAVMs compare them...
Helicobacter pylori, which is a human pathogen associated with gastric and duodenal ulcer, has been shown to express oncofetal antigens Lewis X Y. Although the mammalian glycosyltransferases that synthesize these structures are well characterized, little known about corresponding bacterial enzymes. We report novel beta1,4-galactosyltransferase gene (HpgalT) involved in biosynthesis of lipopolysaccharides H. pylori cloned expressed Escherichia coli. The deduced amino acid sequence protein...