A5054764609- Child and Adolescent Psychosocial and Emotional Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neuroendocrine regulation and behavior
- Cognitive Abilities and Testing
- Neuroscience of respiration and sleep
- Early Childhood Education and Development
- Bipolar Disorder and Treatment
- Genetics and Neurodevelopmental Disorders
- Attention Deficit Hyperactivity Disorder
- Mental Health Research Topics
- Personality Disorders and Psychopathology
- Stress Responses and Cortisol
- Neurotransmitter Receptor Influence on Behavior
- Reading and Literacy Development
- Nicotinic Acetylcholine Receptors Study
- Behavioral Health and Interventions
- Child Abuse and Trauma
- Pediatric Pain Management Techniques
- Epigenetics and DNA Methylation
- Maternal Mental Health During Pregnancy and Postpartum
- Autism Spectrum Disorder Research
- Psychosomatic Disorders and Their Treatments
- Schizophrenia research and treatment
- Mercury impact and mitigation studies
- Musculoskeletal pain and rehabilitation
Université Laval
2006-2024
Vita-Salute San Raffaele University
2006-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2024
Centre for Addiction and Mental Health
2017-2024
University of Toronto
2016-2024
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2024
Institut Universitaire en Santé Mentale de Québec
2012-2023
Harvard University
2021
National Agency for New Technologies, Energy and Sustainable Economic Development
2013
San Raffaele University of Rome
1990-2012
<h3>Context</h3> Childhood separation anxiety disorder can predate panic disorder, which usually begins in early adulthood. Both disorders are associated with heightened sensitivity to inhaled CO<sub>2</sub>and be influenced by childhood parental loss. <h3>Objectives</h3> To find the sources of covariation between hypersensitivity CO<sub>2</sub>, and adulthood measure effect loss on such covariation. <h3>Design</h3> Multivariate twin study. <h3>Participants</h3> Seven hundred twelve young...
Background In man, many different events implying childhood separation from caregivers/unstable parental environment are associated with heightened risk for panic disorder in adulthood. Twin data show that the occurrence of such contributes to explaining covariation between anxiety disorder, panic, and related psychobiological trait CO2 hypersensitivity. We hypothesized early interference infant-mother interaction could moderate interspecific response through genetic control sensitivity...
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The authors investigated the relation of age at onset panic disorder to liability and agoraphobia.Two hundred thirty-one outpatients with were compared 131 surgical on demographic variables familial risk psychiatric disorders. distribution patients' ages several covariates entered in a stepwise survival analysis.The patients had significantly higher rate childhood separation anxiety risks disorder/panic agoraphobia alcoholism. A family history presence influenced disorder.Age may reflect...
Adult patients having schizophrenia (SZ) or bipolar disorder (BP) may have in common neurocognitive deficits. Former evidence suggests impairments several neuropsychological functions young offspring at genetic risk for SZ BP. Moreover, a dose-response relation exist between the degree of familial loading and cognitive impairments. This study examines functioning high-risk (HR) parents (HRSZ) (HRBP) descending from densely affected kindreds.The sample consisted 45 (mean age 17.3 years) born...
While the genetic and environmental contributions to developmental dyslexia ( DD ) have been studied extensively, effects of identified risk susceptibility specified hazardous factors usually investigated separately. We assessed potential gene‐by‐environment GxE interactions on ‐related reading, spelling memory phenotypes. The presence were for DYX1C1 , DCDC2 KIAA0319 ROBO1 genes, seven moderators in 165 nuclear families which at least one member had by implementing a general test...
Evidence shows that maternal care and postnatal traumatic events can exert powerful effects on brain circuitry development but little is known about the impact of early experiences processing rewarding aversive stimuli related to medial prefrontal cortex (mpFC) function in adult life. In this study, unstable environment induced by repeated cross-fostering (RCF) impaired palatable food conditioned place preference disrupted natural for sweetened fluids saccharin test. By contrast, RCF...
Early life events have a crucial role in programming the individual phenotype and exposure to traumatic experiences during infancy can increase later risk for variety of neuropsychiatric conditions, including mood anxiety disorders. Animal models postnatal stress been developed rodents explore molecular mechanisms responsible observed short long lasting neurobiological effects such manipulations. The main aim this study was compare behavioral hormonal young adult animals exposed different...
Direct, blind interviews were used to study the risk for and prevalence of DSM-III-R Axis I II disorders in 93 first-degree relatives outpatients with schizotypal personality disorder (SPD) other disorders. Risks SPD (at a slightly loosened diagnostic threshold) schizoid significantly higher families probands SPD. Schizophrenia was present only among SPD, accounting morbid 4.1 percent. Neither familial risks mood anxiety nor differed two groups relatives. It is suggested that representing...
Abstract The impact of socioeconomic status (SES) and genetic polymorphisms on individual differences for externalized behaviors have often been investigated separately in studies children adults. In a general population sample 607 Italian preadolescents, we examined the independent joint effects SES dopamine receptor D4 ( DRD4 ) serotonin transporter linked promoter region 5-HTTLPR upon rule-breaking aggressive measured with Child Behavior CheckList/6–18. We found evidence, which was based...
Objective: Memory deficits have been shown in patients affected by schizophrenia (SZ) and bipolar (BP)/mood disorder. We recently reported that young high-risk offspring of an parent were impaired both verbal episodic memory (VEM) visual (VisEM). Understanding better the trajectory impairments from childhood to adult clinical status risk populations is crucial for early detection prevention. In multigenerational families densely SZ or BP, our aim was compare observed nonaffected with...