A5019358066- Dementia and Cognitive Impairment Research
- Biomedical and Engineering Education
- BRCA gene mutations in cancer
- Genetics, Bioinformatics, and Biomedical Research
- Parkinson's Disease Mechanisms and Treatments
- Alzheimer's disease research and treatments
- Amyotrophic Lateral Sclerosis Research
- Genetic Neurodegenerative Diseases
- Problem and Project Based Learning
- Smoking Behavior and Cessation
- Sleep and related disorders
- Neurological disorders and treatments
- Family Caregiving in Mental Illness
- Innovations in Medical Education
- Educational and Social Studies
- Neurobiology of Language and Bilingualism
- COVID-19 and Mental Health
- Nutrition and Health Studies
- Consumer Attitudes and Food Labeling
- Sleep and Wakefulness Research
- Health, Environment, Cognitive Aging
- Psychiatry, Mental Health, Neuroscience
- Neurological diseases and metabolism
- Restless Legs Syndrome Research
- Obesity, Physical Activity, Diet
Istituto Superiore di Sanità
2009-2025
National Centre for Disease Prevention and Control
2016-2021
Abstract Background Alzheimer's disease (AD) is frequently accompanied by sleep impairment, which can induce AD-related neurodegeneration. We herein investigated the architecture, cognition, and cerebrospinal fluid (CSF) biomarkers (tau proteins β-amyloid 42 ) during AD progression from subjective cognitive impairment (SCI) to mild (MCI) eventually dementia, compared results with cognitively normal (CN) subjects. Methods included patients affected SCI, MCI, AD, moderate-to-severe in our...
Objective The study investigated whether Protection Motivation Theory (PMT) constructs predicted recommended protective behaviours soon after the Italian lockdown and 1-year later.Design A three-wave longitudinal design was used. Three-hundred-fifty-two adults completed online questionnaires with PMT intention measures assessed during (T1), behaviour 1-month (T2) (T3).Outcome Intentions to adopt (T1) adherence at T2 T3.Results From T3, participants reported less adoption of distance...
<b><i>Background:</i></b> Up to 53.7% of all cases dementia are assumed be due Alzheimer disease (AD), while 15.8% considered vascular (VaD). In Europe, about 3 million AD could 7 potentially modifiable risk factors: diabetes, midlife hypertension and/or obesity, physical inactivity, depression, smoking, and low educational level. <b><i>Aims:</i></b> To estimate the number VaD in Europe Italy attributable these factors....
To validate the adapted Italian version of Non-Motor Symptoms Scale (NMSS), a tool to assess non-motor symptoms (NMS) in Parkinson's disease (PD).A cross cultural adaptation NMSS into and psychometric analysis translated was carried out patients with PD from two university centres-affiliated hospitals. The quality data acceptability, reliability construct validity were analyzed. following standard scales also applied: Hoehn Yahr staging, Unified Disease Rating (UPDRS) part III, Montreal...
The WHO European Programme of Work, 2020-2025 'United Action for Better Health in Europe', backed up by the Regional Director's vision, recognizes need to invest public health leadership towards addressing multifaceted challenges Region. Office Europe collaboration with Italian National Institute (Istituto Superiore di Sanità-ISS) developed first Public Leadership Course support Member States building their capacity. course was delivered blended modality over a period 3 weeks (7-25 November...
The Italian Dementia National Plan was formulated in October 2014 by the Ministry of Health close cooperation with regions, Institute and three major national associations patients carers. main purpose this strategy to provide directive indications for promoting improving interventions dementia field, not limiting specialist therapeutic actions, but particularly focusing on support families throughout pathways care. Four objectives are indicated: 1) promote health- social-care policies; 2)...
Aim Providing an overview of the neuropsychological tests used in Italian memory clinics (defined as Centers for Cognitive Disorders and Dementias—CCDD Italy) diagnosis cognitive disorders dementias. Methods A total 501 CCDD, out all 536 active were surveyed between February 2014 August 2015 to verify characteristics centres who performed a comprehensive assessment (NPA), defined administration at least one test verbal visual episodic memory, attention, constructional praxis, fluency...
Background: Italy has one of the oldest populations in World and more than million dementia cases can be estimated at national level. Objective: The objectives this survey include: 1) to report administrative features professional competencies Centers for Cognitive Disorders Dementias (CCDDs); 2) document possible discrepancies by geographic macro-area; 3) identify CCDDs that are associated with a better quality provision care. Methods: A Italian was conducted between February 2014 December...
The rapid spread of personalized medicine requires professionals to manage the "omics revolution." Therefore, genetics/genomics literacy healthcare should be in line with continuous advances this field, order implement its potential implications for diagnosis, control and treatment diseases. present study investigates effectiveness a distance learning course on genetics genomics targeted at medical doctors. In context project funded by Italian Ministry Health, we developed course, entitled...
Introduction The Free and Cued Selective Reminding Test ( FCSRT ) is the memory test recommended by International Working Group on Alzheimer's disease AD for detection of amnestic syndrome medial temporal type in prodromal . Assessing construct validity internal consistency Italian version thus crucial. Methods was administered to 338 community‐dwelling participants with complaints (57% females, age 74.5 ± 7.7 years), including 34 , 203 Mild Cognitive Impairment, 101 Subjective Memory...
This investigation is aimed at providing information about structural and organizational characteristics of smoking cessation services (SCS) set up within the Italian National Health Service. Local health units hospitals are main institutions connected with SCS which mainly located Department Drug Addiction Lung Breath Care. provide different tobacco-use programs. Although pharmacotherapy always used, a combination therapeutic treatments highly preferred. study shows importance maintaining...
Mild cognitive impairment (MCI) is a nosological entity proposed by Petersen in 1999 with the objective of identifying an early stage dementia. The new diagnostic criteria for dementia, both those promoted International Working Group (IWG) and defined National Institute Aging (NIA), subsequently introduced model that starts preclinical phase, then proceeds prodromal ends phase condition known as subjective disorder (SCD) included between preclinic phases. Most clinicians improperly consider...
People with dementia have special assistance needs. Worldwide problem is to ensure access quality health services. Our study supported by the Italian Ministry of Health reports methodology features a large survey project conducted identify and collect information on social services for people in Italy. Among all regions, about two thousand available individuals disease their caregivers were identified. These included memory clinics, daycare centers residential care facilities, totally or...
Prevalence estimate of amyotrophic lateral sclerosis (ALS) ranged between 1.1/100,000 and 11.2/100,000 inhabitants with different design the study (prospective or retrospective) sample size. The aim this is to conduct for first time an ALS prevalence in Latium region.The was performed Latium, a region located center Italy, population, as January 1, 2016, 5888.472 inhabitants. In region, network 15 clinical centers (of which 4 referral are Rome) 10 local health authorities involved diagnosis...
Background: The activity of caregiving for people affected with Alzheimer's disease (AD) is associated an augmentation in health problems (anxiety, depression, stress, increased mortality), as well social and financial problems. Different methods counselling, to reduce caregiver anxiety have been shown be effective. Methods/Design: This study will a multicenter, prospective, randomized, open-label, blinded-endpoint (PROBE) controlled superiority trial two parallel groups. Two hundred...
Antismoking helplines have become an integral part of tobacco control efforts in many countries, including Italy. The demonstrated efficacy and the convenience telephone based counselling led to fast adoption antismoking helplines. However, information on how these operate actual practice is not often readily available. This paper provides overview Italian Helpline, increasingly popular service for problems operating Italy since 2000. As states, regions nations are contemplating various...
Genetic and genomic literacy of health professionals is utmost importance to realize the full potential personalized medicine. As part a European Union project, we piloted an e-learning course on oncogenomics, primarily targeted physicians, assessed both its effectiveness users' satisfaction.
Implementation of COVID-19 protective behaviours, such as social distancing or frequent hand washing during the lockdown, was critical to prevent spread pandemic. In this cross-sectional study, we examined effect positivity and parochial altruism on implementing health-protective behaviours Italian lockdown. A sample 460 participants completed an online questionnaire that included demographic measures, Positivity Scale measures behaviours. To measure altruism, used a hypothetical dictator...