A5043768958- Cell death mechanisms and regulation
- Venomous Animal Envenomation and Studies
- Mesenchymal stem cell research
- Immune Cell Function and Interaction
- Hepatitis B Virus Studies
- Ion channel regulation and function
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Antimicrobial Peptides and Activities
- Immune cells in cancer
- Cytokine Signaling Pathways and Interactions
- Neurogenesis and neuroplasticity mechanisms
- Traditional Chinese Medicine Analysis
- interferon and immune responses
- NF-κB Signaling Pathways
- Sperm and Testicular Function
- Mitochondrial Function and Pathology
- Plant Virus Research Studies
- Neuroscience and Neural Engineering
- Urologic and reproductive health conditions
- Garlic and Onion Studies
- Medicinal Plant Pharmacodynamics Research
- CAR-T cell therapy research
- Flavonoids in Medical Research
- Pluripotent Stem Cells Research
Razi University
2015-2024
Imam Hossein University
2023
Background: Gastric cancer is the second and fourth most common in Iranian men women, respectively, but it first leading cause of deaths Iran. Most patients with gastric are diagnosed at an advanced stage disease when conventional treatments have no effect on improving survival. So, early detection high priority order to decrease its mortality rate HOTAIR a long non-coding RNA which overexpression has been documented different types human can be considered as potential biomarker. The aim...
Mesenchymal stem cells (MSCs) are known for their ability to induce the conversion of conventional T (Tconvs) into induced regulatory (iTregs) in specific inflammatory contexts. Stable Foxp3 expression plays a major role phenotypic and functional stability iTregs. However, how MSCs stable remains unknown.We first investigated cell-cell contact cytokine secretion by bone marrow-derived (BM-MSCs) on induction, stability, suppressive functions Tregs under various experimental conditions that...
Angiogenesis is a key process in the promotion of cancer and its metastasis. Herein, antiangiogenic activity Salvia officinalis extract fractions was investigated. S. aerial parts were extracted with ethanol successive hexane, ethyl acetate, n-butanol aqueous evaluated for their activities using human umbilical vein endothelial cells (HUVEC) capillary tube formation rat aorta models three-dimensional collagen matrix. Furthermore, antimigrative effects assessed wound healing model. The (ESO)...
To investigate the level of correlation between large-scale deletions mitochondrial DNA (mtDNA) with defective sperm function.In this analytic study, a total 25 semen samples nor- mozoospermic infertile men from North Iran were collected IVF center in an infertility clinic. The swim-up procedure was performed for separation spermatozoa into two groups; (normal motility group and abnormal group) by 2.0 ml Ham's F-10 medium 1.0 semen. After extraction, long-range polymerase chain reaction...
Mitochondria play a crucial role in energy metabolism for the survival and motility of sperm during fertilization. The aim this study was to determine association large-scale mitochondrial DNA deletions with abnormal morphology asthenoteratozoospermic patients.In case-control study, 41 semen samples were collected from 18 normozoospermic healthy men 23 patients, according WHO guidelines. swim-up technique used separation spermatozoa on basis their motility. Long-range polymerase chain...
Lipoid proteinosis (LP) is an autosomal recessive disease. Clinical characteristics of this disease are hoarse voice, scarring the skin, brain calcifications, and eyelid papules (moniliform blepharosis). Mutations in ECM1 gene on 1q21.2 responsible for This study was conducted to investigate mutation spectrum nine Iranian families having at least one LP patient diagnosed clinically.The entire screened using PCR direct sequencing with 12 suspected patients who were referred clinic, along...
Rheumatoid arthritis (RA) is a multifactorial disorder related to the inflammatory response system with debilitating and painful conditions. Both genetic environmental factors, unknown etiology, play important roles in this disease pathogenesis. Recently, TRAF1/C5 (Tumor Necrosis Factor Receptor-Associated 1/Complement Component 5) polymorphism associated increased risk for RA has been studied different populations worldwide, inconsistent results have obtained. rs10818488 allele located on...
Iranian Scorpion (Odontobuthus bidentatus) crude venom change the redox potential of MCF-7 breast cancer cell line and induce apoptosis