A5012803429- Circadian rhythm and melatonin
- Photoreceptor and optogenetics research
- Neurobiology and Insect Physiology Research
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac tumors and thrombi
- Neurotransmitter Receptor Influence on Behavior
- Receptor Mechanisms and Signaling
- Venous Thromboembolism Diagnosis and Management
- Neuroscience and Neuropharmacology Research
- Protease and Inhibitor Mechanisms
Guiyang Medical University
2024
Affiliated Hospital of Guizhou Medical University
2024
Center for Life Sciences
2022-2023
Chinese Institute for Brain Research
2022-2023
Peking University
2022-2023
McGovern Institute for Brain Research
2023
Vision enables both image-forming perception, driven by a contrast-based pathway, and unconscious non-image-forming circadian photoentrainment, an irradiance-based pathway1,2. Although two distinct photoreceptor populations are specialized for each visual task3-6, photoreceptors can additionally contribute to photoentrainment of the clock in different species7-15. However, it is unknown how pathway functionally implement segregation irradiance signals required from contrast image perception....
The master circadian clock generates 24-hour rhythms to orchestrate daily behavior, even running freely under constant conditions. Traditionally, the is considered self-sufficient in sustaining free-running timekeeping via its cell-autonomous molecular clocks and interneuronal communications within neural network. Here, we find a set of bona fide ultradian oscillators Drosophila brain that support timekeeping, despite being located outside circuit lacking gene expression. These extra-clock...
Abstract As a central part of the mammalian brain, prefrontal cortex (PFC) has been implicated in regulating cocaine-induced behaviors including compulsive seeking and reinstatement. Although dysfunction PFC reported animal human users with chronic cocaine abuse, less is known about how involved behaviors. By using two-photon Ca 2+ imaging to simultaneously record tens intact individual networking neurons frontal association (FrA) awake male mice, here we report that systematic acute...
The coexistence of venous thromboembolism (VTE) within patients with cancer, known as cancer-associated thrombosis (CAT), stands a prominent cause mortality in this population. Over recent years, the incidence VTE has demonstrated steady increase across diverse tumor types, influenced by several factors such patient management, tumor-specific risks, and treatment-related aspects. Furthermore, mutations specific genes have been identified potential contributors to increased CAT occurrence...