A5023748606- Advanced MRI Techniques and Applications
- Atomic and Subatomic Physics Research
- Advanced Neuroimaging Techniques and Applications
- Vestibular and auditory disorders
- MRI in cancer diagnosis
- Inhalation and Respiratory Drug Delivery
- Obstructive Sleep Apnea Research
- Ear Surgery and Otitis Media
- Medical Imaging Techniques and Applications
- Ear and Head Tumors
- Quantum, superfluid, helium dynamics
- Hearing, Cochlea, Tinnitus, Genetics
- Advanced Computing and Algorithms
- Sleep and Wakefulness Research
- Ophthalmology and Eye Disorders
- AI and Big Data Applications
- Neurofibromatosis and Schwannoma Cases
- Electron Spin Resonance Studies
- Cerebrovascular and Carotid Artery Diseases
- Cerebrospinal fluid and hydrocephalus
- Ocular Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Radiomics and Machine Learning in Medical Imaging
- Medical Image Segmentation Techniques
- Meningioma and schwannoma management
Canon (Japan)
2018-2025
Nagoya University
2025
Canon Medical Systems Corporation (Japan)
2018-2023
Toshiba (Japan)
1994-2008
The purpose of this study was to assess the extent which improvement in sleep with lemborexant contributed changes interstitial fluid dynamics. 3 methods including diffusion tensor image analysis along perivascular space (DTI-ALPS), dynamic contrast-enhanced method tissue vascular permeability (Ktrans), and choroid plexus volume (CPV) were used. Correlations between these imaging indices parameters (latency persistent [LPS], wake after onset [WASO], total time [TST], efficiency [SE])...
To evaluate the cochlear modiolus with thin-section magnetic resonance (MR) imaging in healthy subjects and patients a large endolymphatic duct sac, to assess whether cochlea is normal or abnormal sac.MR images were obtained 10 ears five volunteers (group 1), 40 20 bilateral sensory hearing loss 2), three two Mondini malformation 3), 12 seven sac 4).In groups 1 2, all modiolar areas larger than 4.0 mm2. In group 3, each was smaller 2.0 4, mm2 eight four ears.Findings this study confirm that...
To prospectively evaluate the sensitivity and specificity of magnetic resonance (MR) imaging in inner ear with a long echo train, three-dimensional (3D), asymmetric Fourier-transform, fast spin-echo (SE) sequence use dedicated quadrature-surface phased-array coil to detect vestibular schwannoma cerebellopontine angle internal auditory canal.In 205 patients (410 ears) symptoms, 1.5-T MR was performed unenhanced 3D SE gadolinium-enhanced gradient-recalled (SPGR) sequences quadrature surface...
A novel MR angiography (MRA) method, swap phase encode extended data (SPEED), was developed. Two one-shot images with the phase-encode directions swapped were collected within a single breath-hold period and processed maximum intensity projection (MIP) to obtain an image. In this study, long echo train two-dimensional rapid acquisition relaxation enhancement (RARE) sequence half-Fourier (half-RARE) used pulmonary MRA images. The MIP image obtained using SPEED technique presented promising...
Saturation transfer contrast (STC) techniques have been employed to decrease the signal intensity of observed water by saturating a broad proton component. The STC pulse, generally spatially nonselective, reduces brain background tissues as well inflowing blood in 3D time-of-flight (TOF) angiography. We present novel technique, slice-selective off-resonance sinc pulse (SORS), which is enhance and suppress stationary tissues. effects SORS other nonselective methods influencing discussed...
Purpose The objective of this study is to evaluate the suitability and performance ultra‐short echo time (UTE) sequences for imaging quantifying deposition nebulized MRI contrast agents in human‐sized lungs. Methods Nebulization clinically used agent or gadolinium‐based nanoparticles were performed using a commercial jet nebulizer isolated ventilated porcine lungs connected 3D‐printed human upper airways replica. MR images acquired on 3T clinical scanner 3D UTE at different flip angles....
This study aims at determining lung distribution of gadolinium-based polysiloxane nanoparticles, AGuIX® (small rigid platform - SRP), as a potential theranostic approach by the pulmonary route.First, aerodynamic size and aerosol output rate were thoroughly characterized. Then, multimodal using magnetic resonance (MR) gamma-camera (GC) imaging allows to assess deposition aerosolised nanoparticles in respiratory tract isolated ventilated porcine lungs.The SRP has proven be radiolabelled...
Magnitude subtraction and complex in dynamic contrast-enhanced three-dimensional magnetic resonance (3D-MR) angiography were compared using a phantom 23 human subjects. In studies, showed far better performance than magnitude subtraction, especially for longer echo times, with thicker slices, without fat suppression. With non-fat-suppressed studies contrast-to-noise ratios comparable to those fat-suppressed studies. subjects, was superior 9 but 14 There no cases which subtraction. Although...
The characteristics of tissue structures can be estimated by comparing images with different diffusion times acquired using the OGSE and PGSE methods. However, for multiple images, it is difficult to make pixel-by-pixel comparison. We attempted a method integrating pixel values these ternary plotting malignant glioma cases. Tumor areas abnormal enhancement, peritumoral signal areas, distant edematous were evaluated. plot provided immediate visual information. It also highlighted similarities...
Motivation: The motivation is to investigate the relationship between sleep and interstitial fluid dynamics influenced by administration of lemborexant, a dual orexin receptor antagonist. Goal(s): goal identify changes in indices related before after lemborexant. Approach: ALPS-index, Ktrans DSC method, choroid plexus volume were assessed as indicators dynamics. Results: indexes on night found correlate with ALPS-index measured evening that night's sleep. In multiple regression analysis, was...
Motivation: The edema around a malignant glioma contains infiltrating tumor cells. motivation for this study was to determine the characteristics of glioma. Goal(s): goal is evaluate gliomas using combination oscillating gradient spin echo and pulsed echo. Approach: ternary plot method used by existing tissue as an internal reference. Results: Edema showed different distribution in relation reference compared other tumors. Impact: Ternary present pixel values obtained from echo, tissues were...
Purpose: Recently, the utility of non-contrast MR endolymphatic hydrops imaging was reported, but pitfall indicated based on T2 preparation pulse sensitiveness to local static magnetic field (B0) inhomogeneity. The purpose this study is clarify effects surrounding environment temporal bone lymphatic fluid signal intensity and attenuated inversion recovery combination (T2prep 3D-FLAIR) technique in human inner ear study.
Extracellular volume fraction mapping (ECV Map) can provide quantitative measurements of myocardial tissue with amyloid deposition and edema. ECV have been shown to correlate well fibrosis. Pixel-wise Maps are calculated from acquired precontrast postcontrast T1 calibrated by blood hematocrit. The maps ECG triggering breath holding. However, measurement is not accurate when heart motion occurs because inconsistent inadequate holding during image acquisition. We present an application...
Array coils play an important role in improving the signal-to-noise ratio (SNR) and achieving parallel imaging; however, one disadvantage of array is nonuniformity their sensitivity. We propose a simple algorithm to enhance blood vessel visualization 3D-TOF-MRA (three-dimensional time-of-flight magnetic resonance angiography) utilizing this surface sensitivity, we apply it MRA data normal volunteers. have verified that peripheral vessels has been remarkably improved.