A5052197097- Multiple Sclerosis Research Studies
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Migraine and Headache Studies
- Infectious Encephalopathies and Encephalitis
- Spine and Intervertebral Disc Pathology
- Ophthalmology and Eye Disorders
- Peripheral Neuropathies and Disorders
- Ultrasound and Hyperthermia Applications
- RNA regulation and disease
- Spinal Fractures and Fixation Techniques
- Neuroinflammation and Neurodegeneration Mechanisms
- Traumatic Brain Injury and Neurovascular Disturbances
- Systemic Lupus Erythematosus Research
- Vascular Malformations Diagnosis and Treatment
- MRI in cancer diagnosis
- Cerebral Venous Sinus Thrombosis
- Neurogenesis and neuroplasticity mechanisms
- Glioma Diagnosis and Treatment
- Bone and Joint Diseases
- Trigeminal Neuralgia and Treatments
- Polyomavirus and related diseases
Inserm
2015-2024
Université de Bordeaux
2015-2024
Hôpital Pellegrin
2012-2024
Neurocentre Magendie
2015-2024
Centre Hospitalier Universitaire de Bordeaux
2015-2024
Centre National de la Recherche Scientifique
2000-2024
Institut de Psychiatrie et Neurosciences de Paris
2024
Kansai Electric Power Hospital
2024
Laboratoire Bordelais de Recherche en Informatique
2016-2024
Institut des Maladies Neurodégénératives
2024
Magnetization transfer imaging (MTI) was initially performed in normal guinea pigs and human volunteers. A magnetization ratio (MTR) calculated the white matter found to be 42%-44%, with less than 2.5% variation, which indicates high reproducibility of measurement. MTI then applied an animal model disease, acute experimental allergic encephalomyelitis (EAE). In this EAE, pathologically proved lesions were edematous essentially no demyelination. MTRs decreased slightly but significantly...
Erdheim-Chester disease is a form of Histiocytosis which involves the adults and distinct from X. It characterized by constant diaphyseal metaphyseal bone involvement predominating in lower links. The diagnosis can readily be envisaged when typical radiological findings are present. Bone may isolated well tolerated, or associated with systemic severe prognosis. We describe three cases women aged 46, 50 73 years. One patient presented lesions, while two others had multiorgan localization....
We attempted to define the role of subtle changes in normal-appearing white matter (NAWM) development disability multiple sclerosis (MS). Twenty-seven clinically definite MS patients with either relapsing-remitting or chronic-progressive courses and 10 sex- age-matched controls entered study. For each patient control, we studied two NAWM areas frontal lobe magnetization transfer imaging (MTI). patients, also calculated MT ratios (MTRs) for three contiguous progressively further from...
To evaluate diffusion-weighted magnetic resonance (MR) imaging in patients with cervical spondylosis and/or myelopathy.A multishot echo-planar sequence calculation of apparent diffusion coefficient (ADC) and tensor (ADT) was applied 36 symptomatic spondylosis. Diffusion-weighted images read by two neuroradiologists were compared T2-weighted fast spin-echo independently three regard to clinical status (n = 36). MR findings a selected subgroup 20 whose confirmed electrophysiologic examination...
Cell-specific imaging has been proposed to increase the potential of magnetic resonance (MRI) for tissue analysis. The hypothezis present work was that following intravenous injection ultra-small particle iron oxide, a contrast agent accumulates in mononuclear phagocyte cells, macrophages with burden would be detectable by MRI within central nervous system at sites inflammatory cellular activity. In experimental autoimmune encephalomyelitis Lewis rats (in which intense macrophage activity...
We set out to study the role of psychiatric comorbidity in evolution migraine medication overuse headache (MOH) by a comparative 41 migraineurs (MIG) and patients suffering from MOH deriving migraine. There was an excess risk mood disorders [odds ratio (OR) = 4.5, 95% confidence interval (CI) 1.5, 13.5], anxiety (OR 5, CI 1.2, 10.7) associated with use psychoactive substances other than analgesics 7.6, 2.2, 26.0) compared MIG. Retrospective order occurrence showed that group, occurred...
<h3>BACKGROUND AND PURPOSE:</h3> FD stent placement is a promising therapy for challenging intracranial aneurysms. Long-term evaluations about angiographic and morphologic results are still missing. This the aim of this multicenter series. <h3>MATERIALS METHODS:</h3> We report our experience 1-year FU in retrospective chart review 65 consecutive subjects with 77 unruptured or recanalized aneurysms that were treated Silk stents at 6 centers France. Both clinical recorded before treatment 12...
To determine MRI predictors for cognitive outcome in patients with early relapsing-remitting multiple sclerosis (MS).Forty-four recently diagnosed clinically definite MS were followed up clinical and evaluations at 1, 2, 5, 7 years underwent brain including magnetization transfer (MT) imaging baseline 2 years. Cognitive evaluation was also performed 56 matched healthy subjects baseline. testing included the Brief Repeatable Battery. Imaging parameters lesion load, parenchymal fraction (BPF),...
Background and Purpose— On top of functional outcome, accurate prediction cognitive outcome for stroke patients is an unmet need with major implications clinical management. We investigated whether location may contribute independent prognostic value to multifactorial predictive models outcomes. Methods— Four hundred twenty-eight consecutive ischemic were prospectively assessed magnetic resonance imaging at 24 72 hours 3 months using the modified Rankin Scale Montreal Cognitive Assessment...
<b><i>Background:</i></b> Ten percent of patients with MS have a progressive course from onset no history relapses or remissions. A smaller subgroup follow similar but single relapse at some point (transitional [TP] MS). To date these been excluded receiving licensed treatments for and most therapeutic trials. <b><i>Objective:</i></b> document the clinical MRI characteristics large cohort patients, including 158 primary (PP) 33 TPMS. Data small reference group 20 secondary (SP) are also...
Apparent diffusion tensor (ADT) measurements on the spinal cord using a pulsed-field-gradient (PFG) multi-shot echo-planar imaging (EPI) sequence are presented. In study of 10 healthy volunteers, obtained rotationally invariant anisotropy information is compared to results by dependent methods. The water diffusivity in direction parallel fibers was found be almost 2.5 times higher than average directions perpendicular and showed cylindrically symmetric characteristics. influence partial...
Object. The goal of this study was to determine the most suitable procedure(s) localize optimal site for high-frequency stimulation subthalamic nucleus (STN) treatment advanced Parkinson disease. Methods. Stereotactic coordinates STN were determined in 14 patients by using three different methods: direct identification on coronal and axial T 2 -weighted magnetic resonance (MR) images indirect targeting which are referred anterior commissure—posterior commissure (AC—PC) line, which, itself,...