A5018362100- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural and Behavioral Psychology Studies
- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Schizophrenia research and treatment
- Evolutionary Psychology and Human Behavior
- Attention Deficit Hyperactivity Disorder
- Neurotransmitter Receptor Influence on Behavior
- Neural dynamics and brain function
- Memory and Neural Mechanisms
- Evolutionary Game Theory and Cooperation
- Neuroscience and Music Perception
- Psychosomatic Disorders and Their Treatments
- Cultural Differences and Values
- Stress Responses and Cortisol
- Psychology of Moral and Emotional Judgment
- Intelligent Tutoring Systems and Adaptive Learning
- EEG and Brain-Computer Interfaces
- Mental Health Treatment and Access
- Personality Traits and Psychology
- Personal Information Management and User Behavior
- Mind wandering and attention
- Emotions and Moral Behavior
- Perfectionism, Procrastination, Anxiety Studies
- Advanced MRI Techniques and Applications
Universidad de la República
2014-2025
University of Groningen
2019
Universidad La República
2019
Netherlands Interdisciplinary Demographic Institute
2019
University of Dundee
2010-2014
University of Aberdeen
2010-2011
The dopamine system has been linked to anhedonia in depression and both the positive negative symptoms of schizophrenia, but it remains unclear how dysfunction could mechanistically relate observed symptoms. There is considerable evidence that phasic signals encode prediction error (differences between expected actual outcomes), with reinforcement learning theories being based on error-mediated associations. It hypothesized abnormal encoding neural underlie schizophrenia by disrupting...
We investigated the differences in brain fMRI signal complexity patients with schizophrenia while performing Cyberball social exclusion task, using measures of Sample entropy and Hurst exponent (H). 13 meeting diagnostic Statistical Manual Mental Disorders, 4th Edition (DSM IV) criteria for 16 healthy controls underwent scanning at 1.5 T. The data both groups participants were pre-processed, characterized extracted. Whole H maps generated analysed. results after adjusting age sex together...
Background. Depression is a prevalent disorder that significantly affects the social functioning and interpersonal relationships of individuals. This highlights need for investigation neural mechanisms underlying these difficulties. Investigation exchanges has traditionally been challenging as such interactions are difficult to quantify. Recently, however, neuroeconomic approaches combine multiplayer behavioural economic paradigms neuroimaging have provided framework operationalize quantify...
Depression significantly affects interpersonal functioning.Social avoidance may play an important role in depression, limiting opportunities and social skills acquisition, contributing to the maintenance of difficulties.In last few years, need for studying interactions using interactive tasks has been highlighted.This study investigated unmedicated depressed (n ϭ 26) matched healthy control participants, a novel computerized decision-making task (the TEAM task).In this task, participants...
Major depressive disorder is characterized by anhedonia, cognitive biases, ruminations, hopelessness and increased anxiety. Blunted responses to rewards have been reported in a number of recent neuroimaging behavioural studies major disorder. In contrast, neural aversive events remain an under-studied area. While selective serotonergic reuptake inhibitors are often effective treating disorder, their mechanism action remains unclear. Following series animal model investigations illness...
Abstract Social comparisons are a core feature of human life. Theories posit that social play critical role in depression and anxiety triggering negative evaluations about the self, as well emotions. We investigated neural basis participants with and/or (MD-SA, n=56) healthy controls (n=47) using functional magnetic resonance imaging (fMRI). While being scanned performed comparison task, during which they received feedback their performance co-player. Upward (being worse than co-player)...
Background Depression is a disabling disorder that significantly impacts on the interpersonal functioning of individuals. However, little known about neural substrates such difficulties. In last few years neuroeconomics, which combines imaging with multiplayer behavioural economic paradigms, has been used to study normal and abnormal interactions. Method This functional magnetic resonance investigate activity in unmedicated depressed participants ( n = 25) matched healthy controls 25)....
Social exclusion is an influential concept in politics, mental health and social psychology. Studies on healthy subjects have implicated the medial prefrontal cortex (mPFC), a region involved emotional information processing, neural responses to exclusion. Impairments interactions are common schizophrenia associated with reduced quality of life. Core symptoms such as delusions usually content. However little known about underpinnings abnormalities. The aim this study was investigate...
Abstract Depression and social anxiety are common disorders that have a profound impact on functioning. The need for studying the neural substrates of interactions in mental using interactive tasks has been emphasized. field neuroeconomics, which combines neuroscience techniques behavioral economics multiplayer such as Ultimatum Game (UG), can contribute this direction. We assessed emotions, behavior, Event‐Related Potentials participants with depression and/or symptoms (MD/SA, n = 63, 57...
Abstract Social comparison is central in human life and can be especially challenging depression social anxiety. We assessed event‐related potentials emotions using a task which participants received feedback on both their own co‐player's performance, with and/or anxiety ( n = 63) healthy controls 72). Participants reported more negative for downward (being better than the co‐player [participant correct, wrong]) upward worse wrong, correct]) comparisons versus even outcomes, these effects...
The iterated prisoner’s dilemma (iPD) game is a well-established model for testing how people cooperate, and the neural processes that unfold after its distinct outcomes have been partly described. Recent theoretical models suggest evolution favors intuitive cooperation, which raises questions on behavioral but also timelines involved. We studied outcome/feedback stage of iPD rounds with electroencephalography (EEG) methods. Results showed signals associated this relate to future choice, in...
Abstract Social comparison is central in human life and can be especially challenging depression social anxiety. We assessed event-related potentials emotions when receiving feedback on both their own a co-player’s performance, participants with and/or anxiety (n=63) healthy controls (n=72). Participants reported more negative for downward (being better than someone else) upward worse) comparisons vs. even outcomes, these effects being stronger At the Medial Frontal Negativity, depressed...
Social difficulties are inherent to social anxiety and critical in depression. A key feature both disorders is avoidance, which leads the loss of opportunities precludes from improving abilities. The need for studying functioning using interactive tasks that immerse subject a context has been highlighted. We developed an task allows measuring avoidance. In each round, participants choose between two categories co-players, with kind partner they would like make team. material terms, it always...
Introduction Preclinical studies have suggested that continuous, long-term opiate exposure may be neurotoxic. There is accumulating evidence for neural and neuropsychological abnormalities in diverse human drug addiction populations. However, the structural behavioural correlates of dependency been less studied than other drugs. Aims We investigated brain structure functioning dependent, treatment-seeking patients receiving Methadone Maintenance Treatment, to test hypotheses regional grey...