- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Mechanical Circulatory Support Devices
- Infectious Aortic and Vascular Conditions
- Cardiovascular Function and Risk Factors
- Transplantation: Methods and Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Cardiovascular Effects of Exercise
- Streptococcal Infections and Treatments
- Congenital Heart Disease Studies
- Atrial Fibrillation Management and Outcomes
- Sports injuries and prevention
- Coronary Interventions and Diagnostics
- Sport Psychology and Performance
- Exercise and Physiological Responses
- Cardiac Ischemia and Reperfusion
- IgG4-Related and Inflammatory Diseases
- Eosinophilic Disorders and Syndromes
- Organ Transplantation Techniques and Outcomes
- Aortic Thrombus and Embolism
University Hospital Dubrava
2013-2024
Necrotizing fasciitis (NF) is an uncommon soft tissue infection, usually caused by toxin-producing virulent bacteria. It characterized widespread fascial necrosis primarily Streptococcus hemolyticus. Shortly after the onset of disease, patients become colonized with their own aerobic and anaerobic microflora from gastrointestinal and/or urogenital tracts. Early diagnosis aggressive multidisciplinary treatment mandatory. We describe three clinical cases NF. The first a 69 years old man...
Mitochondrial dysfunction is one of key factors causing heart failure. We performed a comprehensive analysis expression mitochondrial quality control (MQC) genes in failure.Myocardial samples were obtained from patients with ischemic and dilated cardiomyopathy terminal stage failure donors without disease. Using quantitative real-time PCR, we analysed total 45 MQC belonging to biogenesis, fusion-fission balance, unfolded protein response (UPRmt), translocase the inner membrane (TIM)...
Background: Hyperimmune response and cytokine release post-reperfusion might occur after orthotopic heart transplantation (HTx). Intraoperative hemoadsorption (HA) has been introduced to remove such elevated cytokines. We aimed analyze the effect of intraoperative HA in patients undergoing HTx. Methods: Between 2018 2022, 40 consecutive HTx who underwent integrated into cardiopulmonary bypass were compared 41 historical controls. Primary outcome measures included postoperative hemodynamic...
To assess the mental health and experience of sport-related harassment abuse elite aquatic athletes to analyze it in relation gender discipline.Cross-sectional study using an anonymous survey.The FINA World Championships 2019.Registered disciplines swimming, diving, high water polo, artistic open swimming.Athletes completed online or paper-based questionnaire.The main outcome measures included screening for depression (10-item version Center Epidemiological Studies Depression Scale revised),...
This study assessed the experiences of elite aquatic athletes with coronavirus disease 2019 (COVID-19) during first World Championship conducted without social distancing and an isolation "bubble". An online questionnaire was completed by 812 (22.7 ± 5.9 years, 467 females) to provide data on demographics, sports activity, severe acute respiratory syndrome 2 (SARS-CoV-2) infection rates, symptoms, reinfection, vaccination status, psychological aspects. The answers revealed that 49.4% had...
Background: It has recently been shown that cardiac-specific troponin I concentrations in first morning urine samples can be measured with commercially available tests. Due to their accumulation the urine, scientific papers indicate a potential predictive value for cardiovascular diseases. Therefore, aim of this study was compare concentration cardiac patients severe aortic stenosis and healthy population. Patients Methods: Blood were collected from 34 individuals (17 female) at University...
The world has suffered over the past year under COVID-19. Unfortunately, people still are getting sick from other, also severe, diseases. Although COVID-19 infection is present, patients need treatment for other life-threatening conditions. We present case of a 36-year-old patient with severe infective endocarditis large abscess aortic root, who positive. Definitive diagnostics and were avoided due to infection. In end, emergent surgery was indicated acute cardiac decompensation development...
Surgical repair for regurgitant bicuspid aortic valve (BAV) is promising but underutilized due to perceived complexities and lack of long-term data. This study evaluated the efficacy valve-sparing root remodeling (VSRR) or isolated combined with calibrated external ring annuloplasty in BAV versus tricuspid (TAV) patients. All patients operated on regurgitation and/or aneurysm at our institution between 2014 2022 were included entered into Aortic Valve Insufficiency ascending aorta Aneurysm...
ABSTRACT Objective To assess the mental health and experience of sport-related harassment abuse athletes participating in FINA World Championships 2019, to analyse it relation gender aquatic disciplines. Design Cross-sectional study using an anonymous questionnaire. Methods During Championships, registered (swimmers, divers, high water polo players, artistic swimmers, open-water swimmers) completed a survey including main outcome measures depression (CES-D-10), eating disorders (BEDA-Q),...
Objective: To compare the intraoperative quality of coronary anastomoses performed with or without cardiopulmonary bypass using transit time flow measurement (TTFM) parameters. Methods: We collected data from 588 consecutive patients who underwent surgical revascularization. retrospectively reviewed two groups: 411 (CABG group) and 177 off-pump (OPCABG group). Transit flow parameters: mean graft (MGF), pulsatile index (PI), diastolic filing (DF) were measured for each patient. Results:...
Background: Strain imaging is an established method for the accurate quantification of left ventricular function and global longitudinal strain (GLS) has been shown to be a superior marker contractility than ejection fraction (EF), also good prognosis patients with aortic stenosis (AS).We prospectively analyzed GLS in context other relevant clinical parameters severe preserved EF.Patients Methods: We preoperatively measured 42 EF > 45% AS.GLS was obtained using 2D speckle tracking...