A5002957254- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Cardiovascular Conditions and Treatments
- Congenital Diaphragmatic Hernia Studies
- Coronary Artery Anomalies
- Pulmonary Hypertension Research and Treatments
- Cardiovascular Issues in Pregnancy
- Tracheal and airway disorders
- Mechanical Circulatory Support Devices
- Congenital Anomalies and Fetal Surgery
- Vascular anomalies and interventions
- IL-33, ST2, and ILC Pathways
- Atherosclerosis and Cardiovascular Diseases
- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Cardiac Imaging and Diagnostics
- Transplantation: Methods and Outcomes
- Cardiac Arrhythmias and Treatments
- Renal and Vascular Pathologies
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Aortic aneurysm repair treatments
Centre National de la Recherche Scientifique
2021-2025
Hôpital de la Timone
2020-2025
Aix-Marseille Université
2021-2025
Centrale Marseille
2021-2025
Assistance Publique Hôpitaux de Marseille
2021-2024
Montreal Heart Institute
2018-2022
Centre Hospitalier Universitaire Sainte-Justine
2021
Université de Montréal
2018-2020
Centre Hospitalier Universitaire de Besançon
2018-2020
Délégation Paris 5
2017-2018
Abstract Fontan-Associated Liver Disease (FALD) is a dramatically emerging problem even if not precisely defined in term of debated diagnosis and surveillance protocols. We analyze FALD prevalence, clinical impact implications European cohort patients. It’s retrospective observational multicenter study including Fontan patients operated between 1990 2022. Anatomical, clinical, surgical liver-related data were collected, defining as spectrum time-related structural–functional liver...
Abstract Objective Epicardial adipose tissue (EAT) is a visceral fat that has been associated with coronary artery disease and atrial fibrillation. Previous work revealed EAT exhibits beige features. Methods First, new pan‐genomic microarray analysis was performed on previously collected paired human thoracic subcutaneous AT (thSAT) from the EPICAR study ( n = 31) to decipher specific immune signature its link browning genes. Then, adaptive (T B cells) innate lymphoid cell (ILC1, ILC2, ILC3)...
Remodelling with extra-aortic ring annuloplasty has emerged as an alternative approach to root reimplantation. However, no studies have yet compared outcomes between procedures. The aim of this study was compare mid-term in patients undergoing reimplantation versus remodelling annuloplasty.From 2001 2017, 142 underwent (n = 83, 48 ± 13 years) or a technique 59, 12 at the Montreal Heart Institute. No differences were observed incidence connective tissue disease (24% vs 29%, P 0.9)...
Our goal was to evaluate the outcome of valve-sparing root replacement (VSRR) and compare outcomes those patients having composite valve-graft conduit aortic (CVG-ARR) in a cohort with aneurysm ± valve insufficiency, without valvular stenosis. Although procedures are preferable young patients, there is lack comparative data comparable patients.
Abstract OBJECTIVES Three-dimensional (3D) modelling of aortic leaflets remains difficult due to insufficient resolution medical imaging. We aimed model the coaptation and load-bearing surfaces adapt this workflow aid in design valve neocuspidizations. METHODS Geometric morphometrics, using landmarks semilandmarks, was applied geometric determinants from computed tomography, followed by an isogeometric analysis Non-Uniform Rational Basis Splines (NURBS). Ten models were generated, measuring...
To determine the early, intermediate and long-term outcomes of pulmonary atresia with ventricular septal defect (PA/VSD) Types I, II III initially palliated by a right ventricle to artery (RVPA) connection.We performed retrospective study from 2000 2014 that included 109 patients PA/VSD who had undergone an RVPA connection (tetralogy Fallot Type IV excluded). The end-points this strategy were adequate tree post-palliation, second palliation, biventricular repair, pressure post-biventricular...
The physiological repair of the congenitally corrected transposition great arteries (ccTGA) has been associated with a long-term risk right ventricular dysfunction and tricuspid valve regurgitation. On other side, anatomical restoration left ventricle in systemic position hypothesized to improve outcomes. aim this study was determine results repair.Between 1990 2015, 39 patients underwent an ccTGA. median age 7 years (range from 8 days 42.8 years). Eighteen (46%) had double switch. Of these,...
Infants with congenital heart disease are at risk of impaired neurodevelopment, which frequently manifests as motor delay during their first years life. This is multifactorial in origin and environmental factors, such a limited experience prone, may play role. In this study, we evaluated the development prospective cohort 71 infants (37 males) 4 months age using Alberta Infant Motor Scales (AIMS). We used regression analyses to determine whether 4-month AIMS scores predict ability walk by 18...
More than half of infants with complex congenital heart disease (CHD) will have a neurodevelopmental disorder multifactorial causes. The preoperative period represents time-window during which neonates CHD are in state hypoxia and hemodynamic instability, fosters the emergence brain injuries and, thus, affects early networks outcomes. Currently, there is no consensus regarding optimal age for cardiac surgery terms outcomes, its definition real challenge. Our aim to determine relationship...
We describe in a prospective study, novel surgical technique for the management of hypoplastic left heart syndrome inspired by hybrid Norwood approach.This new neonatal palliation comprises replacement patent ductus arteriosus (PDA) and aortic arch plasty with pulmonary homograft associated banding both arteries atrial septectomy, under cardiopulmonary bypass without clamping cardioplegia. Initial results led to tightening artery band from 3.5 mm 2.5 mm.From July 2014 May 2016, 15 patients...
Right ventricular failure is one of the most feared complications after implantation a left assist device. We provide technical details for simplified, percutaneous approach to temporary right heart support.
Introduction: Patent ductus arteriosus (PDA) is common in preterm infants and contributes to morbidity mortality. Several studies have shown the feasibility safety of percutaneous PDA closure. Minimally invasive surgical ligation by anterior thoracotomy an alternative, bedside technique for closure very low birth weight infants. Our study aimed compare short- medium-term mortality between minithoracotomy transcatheter Methods: From 2010 2020, 92 <1,600 g underwent two centers: 44...