A5083165984- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Coronary Artery Anomalies
- Tracheal and airway disorders
- Mechanical Circulatory Support Devices
- Cardiovascular Issues in Pregnancy
- Pulmonary Hypertension Research and Treatments
- Transplantation: Methods and Outcomes
- Cardiac Arrest and Resuscitation
- Infective Endocarditis Diagnosis and Management
- Aortic aneurysm repair treatments
- Vascular anomalies and interventions
- Cystic Fibrosis Research Advances
- Cardiac Arrhythmias and Treatments
- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Kawasaki Disease and Coronary Complications
- Cardiac and Coronary Surgery Techniques
- Electrospun Nanofibers in Biomedical Applications
- Neonatal and Maternal Infections
- Sepsis Diagnosis and Treatment
- Cardiac Ischemia and Reperfusion
- Infectious Aortic and Vascular Conditions
Assistance Publique – Hôpitaux de Paris
2016-2025
Hôpital Necker-Enfants Malades
2019-2025
Université Paris Cité
2017-2025
Institut Necker Enfants Malades
2019-2022
Inserm
2013-2021
Hôpital Marie Lannelongue
2013-2021
Institut du Thorax
2021
Délégation Paris 5
2017-2020
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2020
Master's College
2019
BACKGROUND: Sudden cardiac death is the most common cause of in childhood hypertrophic cardiomyopathy (HCM). Recently, 2 risk scores have been developed to estimate 5-year sudden death. We aimed assess their respective performances an independent cohort. METHODS: All patients with HCM aged <18 years from a single center were retrospectively included between 2003 and 2023. Risk-Kids PRIMaCY calculated at diagnosis during follow-up. The primary composite outcome sustained ventricular...
Abstract OBJECTIVES Anomalous aortic origin of a coronary artery (AAOCA) is the second leading cause sudden death in children and young adults. The most threatening anatomy an interarterial intramural course, both probably involved ischaemic phenomena death. treatment AAOCA remains controversial. Most published studies describe results unroofing technique. Our study aims to evaluate different surgical approach. METHODS From 2005 2019, 61 patients were operated on for (median age 14.7 years)....
Postoperative left atrioventricular valve (LAVV) dysfunction is known to be the principal risk factor influencing outcome after repair of all types septal defect (AVSD). The purpose present study was identify factors for reoperation and assess outcomes LAVV dysfunction.Records 412 patients who underwent anatomical different AVSD from January 2000 July 2012 were reviewed. group (n = 60) included 13 additional whom ± performed in a primary institution. Outcomes, independent factors, death...
As part of a program targeted at developing resorbable valved tube for replacement the right ventricular outflow tract, we compared three biopolymers (polyurethane [PU], polyhydroxyalkanoate (the poly(3-hydroxybutyrate-co-3-hydroxyvalerate-co-4-hydroxyvalerate) [PHBVV]), and polydioxanone [PDO]) two biofunctionalization techniques (using adipose-derived stem cells [ADSCs] or arginine-glycine-aspartate [RGD] peptide) in rat model partial inferior vena cava (IVC) replacement. Fifty-three...
To determine the early, intermediate and long-term outcomes of pulmonary atresia with ventricular septal defect (PA/VSD) Types I, II III initially palliated by a right ventricle to artery (RVPA) connection.We performed retrospective study from 2000 2014 that included 109 patients PA/VSD who had undergone an RVPA connection (tetralogy Fallot Type IV excluded). The end-points this strategy were adequate tree post-palliation, second palliation, biventricular repair, pressure post-biventricular...
The presence of single coronary artery (CA) in the arterial switch operation (ASO) for neonatal treatment with transposition great arteries (TGA) has been reported to be an independent risk factor early death after surgical repair and late reintervention. study objective was evaluate mortality CA stenosis at long term ASO TGA CA.Between January 1987 2010, 979 neonates underwent ASO, which 73 had a (7.5% all cohort): right ostium posterior left loop most frequent pattern (63%), followed by...
The two main objectives of this single-center, retrospective study were to analyze the outcomes and identify independent predictors 30 day long-term mortality in case cardiopulmonary resuscitation requiring extracorporeal life support (ECLS) elderly patients. From October 2004 May 2014, 163 patients with a mean age 75.5 years (range 70-91) required veno-arterial ECLS. indication was postcardiotomy cardiogenic shock (79.6%). Extracorporeal duration averaged 5.6 ± 4.3 days. Thirty-day 72% (n =...
Dilated cardiomyopathy (DCM) is the most common childhood and associated with considerable early mortality. Heart transplantation often only viable life-saving option. Pulmonary artery banding (PAB) has been recently proposed as a bridge or alternative to for DCM. In our cohort, PAB was selectively addressed heritable DCM congenital left ventricle aneurysm (CLVA). This study aimed describe clinical evolution reverse remodeling (LVRR) over time (6 months 1 year after surgery). Ten patients...
Repair of tetralogy Fallot (ToF) can be challenging in the presence an abnormal coronary artery (CA) 5-12% cases. The aim this study was to report our experience with ToF repair without systematic use a right ventricle-to-pulmonary (RV-PA) conduit.We conducted monocentric retrospective from 2000 2016, including 943 patients who underwent biventricular repair, whom 8% (n = 76) presented CA. Mean follow-up time 50 months (1 month-18 years).The most frequent CA anomaly left descending arising...
Abstract Aims The implantable cardioverter defibrillator (ICD) has been increasingly used in children. Both epicardial and transvenous approaches are used, with controversy regarding the best option no specific recommendations. We aimed to compare outcomes associated vs. ICDs Methods results Data were analysed from a retrospective study including all patients &lt;18-year-old implanted an ICD tertiary centre 2003 2021. Outcomes compared between ICDs. A total of 122 children (mean age 11.5...
We describe in a prospective study, novel surgical technique for the management of hypoplastic left heart syndrome inspired by hybrid Norwood approach.This new neonatal palliation comprises replacement patent ductus arteriosus (PDA) and aortic arch plasty with pulmonary homograft associated banding both arteries atrial septectomy, under cardiopulmonary bypass without clamping cardioplegia. Initial results led to tightening artery band from 3.5 mm 2.5 mm.From July 2014 May 2016, 15 patients...
We present the case of a 60-year old woman with ruptured thoraco-abdominal aortic aneurysm (TAAA). It was Type IV TAAA in Crawford Classification. A mycotic origin suspected as she had known history lymphocytic lymphoma. She underwent replacement good surgical result. Histopathological examination revealed destruction layers due to inflammatory lymphomatous infiltration. The patient fully recovered.
Abstract OBJECTIVES Aortic root and ascending aorta replacements (AARs) are rarely required in the paediatric population. We report here a series of AAR performed young children using different surgical techniques. METHODS Between 1995 2017, 32 under age 10 years (median 5.4 years) underwent procedures at our institution. Twenty-two (69%) had connective tissue disease (infantile Marfan syndrome or Loeys–Dietz syndrome). 11 composite graft with mechanical prosthesis 21 valve-sparing (10...
Abstract OBJECTIVES A double orifice of the left atrioventricular valve (LAVV) associated with septal defects (AVSD) can significantly complicate surgical repair. This study reports our experience AVSD repair over 3 decades, special attention to zone apposition (ZoA) main orifice, and presents a technique hemivalve pericardial extension in specific situations. METHODS We performed retrospective from 1987 2016 on 1067 patients whom 43 (4%) had plus 2 additional who required LAVV enlargement....
Patients with end-stage pulmonary arterial hypertension due to congenital heart disease have limited access heart-lung transplantation or double-lung transplantation. We aimed assess the effects of a high-priority allocation program established in France 2007. conducted retrospective study compare waitlist and posttransplantation outcomes before versus after implementation program. included 67 consecutive patients (mean age at listing, 33.2 ± 10.5 years) listed for from 1997 2016. At one...
Anomalous aortic origin of coronary arteries is a rare congenital heart disease that can be associated with sudden death. We present the case young patient who sustained cardiac arrest revealing an anomalous right artery. Unroofing and pericardial enlargement artery ostia was performed actually asymptomatic.
Background: Morphology of the left ventricular outflow tract (LVOT) in atrioventricular septal defects (AVSDs) has been reported to be at risk for development obstruction. The purpose present study was identify incidence, factors, and surgical outcomes subaortic stenosis repaired AVSDs. Methods: Records 427 consecutive patients who underwent anatomical repair all types AVSDs from January 2000 December 2012 were reviewed. Outcomes, independent reoperation, death analyzed. Results: In a median...
<title>Abstract</title> Background. Children with advanced pulmonary disease due to cystic fibrosis (CF) are at risk of acute respiratory failure exacerbations leading their admission pediatric intensive care units (PICU). The objectives this study were determine short and medium-term outcomes children CF admitted PICU for exacerbation identify prognosis factors. Methods. This retrospective monocentric included patients less than 18 years old the a French university hospital between 2000...
Abstract Background Children with advanced pulmonary disease due to cystic fibrosis (CF) are at risk of acute respiratory failure exacerbations leading their admission pediatric intensive care units (PICU). The objectives this study were determine short and medium-term outcomes children CF admitted PICU for exacerbation identify prognosis factors. Methods This retrospective monocentric included patients less than 18 years old the a French university hospital between 2000 2020. Cox...