Lixing Cao

ORCID: 0000-0001-6602-7730
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About
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Research Areas
  • Enhanced Recovery After Surgery
  • Endometriosis Research and Treatment
  • Reproductive System and Pregnancy
  • Acupuncture Treatment Research Studies
  • Gastrointestinal motility and disorders
  • Selenium in Biological Systems
  • Pharmacological Effects of Natural Compounds
  • Medical Research and Treatments
  • Ferroptosis and cancer prognosis
  • Colorectal Cancer Surgical Treatments
  • Cardiac, Anesthesia and Surgical Outcomes
  • Traditional Chinese Medicine Studies
  • Ectopic Pregnancy Diagnosis and Management
  • Glutathione Transferases and Polymorphisms
  • Circular RNAs in diseases
  • Ion Channels and Receptors
  • Complementary and Alternative Medicine Studies
  • Gastric Cancer Management and Outcomes
  • Estrogen and related hormone effects
  • Genomics, phytochemicals, and oxidative stress
  • Diet and metabolism studies
  • Nutrition and Health in Aging
  • Endometrial and Cervical Cancer Treatments
  • Trace Elements in Health
  • Helicobacter pylori-related gastroenterology studies

Guangzhou University of Chinese Medicine
2015-2025

China Agricultural University
2021-2024

Guangdong Provincial Hospital of Traditional Chinese Medicine
2008-2024

CHN Energy (China)
2021

First Affiliated Hospital of Guangzhou University of Chinese Medicine
2012

Endometriosis is a common benign disease in women of reproductive age. It has been defined as disorder characterized by inflammation, compromised immunity, hormone dependence, and neuroangiogenesis. Unfortunately, the mechanisms endometriosis have not yet fully elucidated, available treatment methods are currently limited. The discovery new therapeutic drugs improvements existing schemes remain focus research initiatives. Chinese medicine can improve symptoms associated with endometriosis....

10.3389/fphar.2020.00147 article EN cc-by Frontiers in Pharmacology 2020-03-06

Abstract Temozolomide (TMZ) resistance is the main challenge in management of glioma patients. Heparanase can mediate secretion and function exosomes, which are considered to be a promising molecular delivery system for cancer therapy. Therefore, this study aimed investigate whether heparanase‐mediated exosomes was related TMZ glioma. upregulated TMZ‐resistant cells, overexpression heparanase led increased U87 cells TMZ. Knockdown sensitivity U251 (U251R) promoted from coculture with derived...

10.1111/cas.14984 article EN cc-by-nc-nd Cancer Science 2021-05-26

•People previously diagnosed with cancer are at a higher risk of diabetes than the noncancer population.•Diabetes remains elevated for majority types studied.•Shorter survival duration and longer follow-up period factors diabetes.•Early prevention effective intervention among survivors require attention. BackgroundDiabetes is considered as an established factor development. However, link between inconclusive. The hypothesis this study was to assess hazard ratio (HR) incidence in compared HR...

10.1016/j.esmoop.2021.100218 article EN cc-by-nc-nd ESMO Open 2021-07-22

Introduction: Previous studies indicated that Wuda Granule (WDG) has been applied in the treatment of gastrointestinal motility disorder (GMD), but effect and underlying mechanisms is yet to be elucidated. This study aimed explore mechanism pharmacological WDG for GMD via network analysis, verification animal experiments clinical experiments. Methods: The chemical components were identified from Traditional Chinese Medicine Systems Pharmacology Database (TCMSP,...

10.3389/fphar.2023.1237686 article EN cc-by Frontiers in Pharmacology 2023-08-21

BACKGROUNDDuring the perioperative period, characteristic therapy of traditional Chinese medicine is effective in improving postoperative rehabilitation.In large-scale hospitals practicing medicine, there accumulating experience related to promotion fast recovery period. AIMTo evaluate efficacy and safety Yikou-Sizi powder hot compress on Shenque acupuncture point combined with rapid rehabilitation technique. METHODSThis prospective, multicenter, randomized, controlled study included two...

10.3748/wjg.v26.i23.3271 article EN cc-by-nc World Journal of Gastroenterology 2020-06-20

Combination of intermittent fasting and chemotherapy has been drawn an increasing attention because the encouraging efficacy. In this study, we evaluated anti-cancer effect combination glucose limitation selenite (Se), a representative inorganic form selenium, that is preferentially accumulated in tumors. Results showed cytotoxic on cancer cells, but not normal was significantly enhanced response to limitation. Furthermore, vivo therapeutic efficacy combining with dramatically improved...

10.3390/cancers14020345 article EN Cancers 2022-01-11

Endometriosis is a common gynecological disease and causes severe chronic pelvic pain infertility. Growing evidence showed that traditional Chinese medicine (TCM) plays an active role in the treatment of endometriosis. ELeng Capsule (ELC) formula used for endometriosis several years. However, mechanisms ELC have not been fully characterized. In this study, network pharmacology mRNA transcriptome analysis were to study various therapeutic targets ELC. As result, 40 compounds are identified,...

10.3389/fphar.2021.674874 article EN cc-by Frontiers in Pharmacology 2021-06-18

Abstract Xanthohumol is a principal prenylated chalcone isolated from hops. Previous studies have shown that xanthohumol was effective against various types of cancer, but the mechanisms, especially direct targets for to exert an anticancer effect, remain elusive. Overexpression T‐lymphokine‐activated killer cell‐originated protein kinase (TOPK) promotes tumorigenesis, invasion and metastasis, implying likely potential targeting TOPK in cancer prevention treatment. In present study, we found...

10.1002/ptr.7799 article EN Phytotherapy Research 2023-03-07

Abstract Postoperative gastrointestinal disorder (POGD) was a common complication after surgery under anesthesia. Strategies in combination with Traditional Chinese Medicine and Western medicine showed some distinct effects but standardized clinical practice guidelines were not available. Thus, multidisciplinary expert team from various professional bodies including the Perioperative Anesthesia Professional Committees of Association Integrative (CAIM), jointly Gansu Province Clinical...

10.1111/jebm.12587 article EN cc-by Journal of Evidence-Based Medicine 2024-03-01

AIMTo investigate the effects of Xiangbin prescription (XBP), a Chinese herbal concoction, on gastrointestinal motility. METHODSForty healthy volunteers were recruited for this randomized controlled trial XBP.Antroduodenojejunal manometry was used to monitor

10.3748/wjg.v23.i16.2987 article EN cc-by-nc World Journal of Gastroenterology 2017-01-01

Surgery is the primary curative treatment for patients with nonmetastasized colorectal cancer (CRC). Rate of complications, morbidity, mortality, and overall survival CRC are factors associated speed recovery following surgery. Wuda granule (WD) a traditional Chinese medicine (TCM) prescription used to promote rapid after However, specific mechanism action WD has not been characterized. Our study included 60 clear histopathological evidence colon or rectal who underwent laparoscopic surgery...

10.1155/2020/5068268 article EN cc-by Evidence-based Complementary and Alternative Medicine 2020-01-01

Most patients who undergo abdominal surgery recover bowel movements within a week; however, some suffer prolonged intestinal paralysis or postoperative ileus (POI) leading to complications, such as infection and adhesions, which can extend hospitalization increase readmission rates, consequently increasing healthcare costs. Chinese medicine is effective for accelerating the recovery of gastrointestinal function after surgery. Xiangbin prescription (XBP) standard this purpose in our hospital;...

10.1186/s13063-018-2484-z article EN cc-by Trials 2018-02-27
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