Junhong Zhang

ORCID: 0000-0003-0611-9478
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Research Areas
  • Plant Molecular Biology Research
  • Plant Reproductive Biology
  • Plant Stress Responses and Tolerance
  • Plant tissue culture and regeneration
  • Plant Gene Expression Analysis
  • Psoriasis: Treatment and Pathogenesis
  • Plant nutrient uptake and metabolism
  • Photosynthetic Processes and Mechanisms
  • Chromosomal and Genetic Variations
  • Plant Disease Resistance and Genetics
  • Seed Germination and Physiology
  • Plant-Microbe Interactions and Immunity
  • Dermatology and Skin Diseases
  • Lung Cancer Treatments and Mutations
  • Plant Virus Research Studies
  • CRISPR and Genetic Engineering
  • Plant Genetic and Mutation Studies
  • Lung Cancer Diagnosis and Treatment
  • Asthma and respiratory diseases
  • Lung Cancer Research Studies
  • Cancer-related molecular mechanisms research
  • Colorectal Cancer Treatments and Studies
  • Insect Resistance and Genetics
  • Polysaccharides and Plant Cell Walls
  • Respiratory viral infections research

Guangzhou University of Chinese Medicine
2008-2024

Fujian Agriculture and Forestry University
2024

Zhejiang A & F University
2013-2024

Army Medical University
2023-2024

Wuhan University
2013-2024

Huazhong Agricultural University
2011-2024

Zhongnan Hospital of Wuhan University
2013-2024

Guangdong Academy of Sciences
2024

South China Normal University
2024

The Affiliated Yongchuan Hospital of Chongqing Medical University
2024

The Dof (DNA binding with One Finger) family encoding single zinc finger proteins has been known as a of plant-specific transcription factors. These factors are involved in variety functions importance for different biological processes plants. In the current study, we identified 34 genes tomato, distributed on 11 chromosomes. A complete overview SlDof tomato is presented, including gene structures, chromosome locations, phylogeny, protein motifs and evolution pattern. Phylogenetic analysis...

10.1111/jipb.12043 article EN Journal of Integrative Plant Biology 2013-03-06

Universal stress protein (USP) appears to play an active role in the abiotic response, but their functions remain largely unknown plants. A USP gene (SpUSP) was cloned from wild tomato (Solanum pennellii) and functionally characterized cultivated present study. The SpUSP transcript is abundantly accumulated leaf stomata its expression varied with circadian rhythm. remarkably induced by dehydration, salt stress, oxidative phytohormone abscisic acid (ABA) etc. This predominantly localized...

10.1093/jxb/ers220 article EN cc-by-nc Journal of Experimental Botany 2012-08-21

Previous studies have demonstrated a significant difference in clinical characteristics between patients with non‑small cell lung cancer (NSCLC) harboring exon 19 deletion (19‑del) and an point mutation (21‑L858R) EGFR. The present retrospective study aimed to investigate the differential prognosis NSCLC 19‑del 21‑L858R mutations. follow‑up data of 137 treated at Zhongnan Hospital Wuhan University (Wuhan, Hubei, China) August 2012 2016, who were diagnosed stage IIIB‑IV either or mutations,...

10.3892/ol.2019.10715 article EN Oncology Letters 2019-08-06

Abstract Background Although some psychological processes, such as stigma and self-efficacy, affect the complicated relationship between social support depressive symptoms, few studies explored a similar mechanism among individuals with substance use disorders (SUDs). Hence, this research investigates mediating effects of moderating self-efficacy that affects symptoms. Methods The study included 1040 Chinese participants SUDs completed series self-report questionnaires. R software was used...

10.1186/s12888-022-03740-6 article EN cc-by BMC Psychiatry 2022-02-15

Summary The plant‐specific NAC ( N AM , A TAF 1,2, C UC 2) transcription factors play significant roles in diverse physiological processes. In this study, we determined the regulation of a stress‐related tomato Solanum lycopersicum ) 1 Sl 1) factor at both transcriptional and post‐translational level. protein was found to be stable presence proteasome‐specific inhibitor MG 132 or 115 ubiquitinated plant cells, suggesting that is subject ubiquitin–proteasome system‐mediated degradation....

10.1111/nph.12096 article EN New Phytologist 2012-12-21

The developmental competence of oocytes during in vitro maturation (IVM) is compromised due to asynchronous nuclear and cytoplasmic maturation. To improve IVM efficiency, a pre-maturation culture or two-step strategy has been established, involving meiosis arrest induced by pharmacological agents provide with sufficient time synchronize the nucleus cytoplasm. C-type natriuretic peptide (CNP), which demonstrated function as an oocyte inhibitor (OMI) many species, provides new alternative...

10.1371/journal.pone.0132318 article EN cc-by PLoS ONE 2015-07-07

As a major family of plant-specific transcription factors, SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) genes play vital regulatory roles in plant growth, development and stress responses. In this study, 18 SPL were identified cloned from Betula luminifera. Two zinc finger-like structures nuclear location signal (NLS) segments existed the SBP domains all BlSPLs. Phylogenetic analysis showed that these clustered into nine groups (group I-IX). The intron/exon structure motif composition highly...

10.3389/fpls.2018.00608 article EN cc-by Frontiers in Plant Science 2018-05-04

8093 Background: SCLC is characterized by a high rate of proliferation and poor prognosis, new therapies are urgently needed. B7-H3 highly expressed in SCLC. HS-20093, B7-H3-targeted antibody-drug conjugate (ADC), demonstrated antitumor activity advanced solid tumors the dose escalation part ARTEMIS-001 study (Jie Wang et al., JCO, 2023) (NCT05276609). Here, we present results on efficacy safety expansion doses patients (pts) with from phase 1a/b. Methods: consisted (1a) (1b) part. Pts were...

10.1200/jco.2024.42.16_suppl.8093 article EN Journal of Clinical Oncology 2024-06-01

Many hybrid proline-rich protein (HyPRP) genes respond to biotic and abiotic stresses in plants, but little is known about their roles other than as putative cell-wall structural proteins. A HyPRP1 gene encodes a with domain, an eight-cysteine motif was identified from our previous microarray experiments on drought-tolerant tomato. In this study, the expression of tomato suppressed under various stresses, such drought, high salinity, cold, heat, oxidative stress. Transgenic functional...

10.3389/fpls.2016.00967 article EN cc-by Frontiers in Plant Science 2016-06-29

Abstract Tomato (Solanum lycopersicum) is a highly valuable fruit crop, and yield one of the most important agronomic traits. However, genetic architecture underlying tomato yield-related traits has not been fully addressed. Based on ∼4.4 million single nucleotide polymorphisms obtained from 605 diverse accessions, we performed comprehensive genome-wide association study for 27 in tomato. A total 239 significant associations corresponding to 129 loci, harboring many previously reported...

10.1093/plphys/kiab230 article EN PLANT PHYSIOLOGY 2021-05-15
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