A5100386570- Hepatocellular Carcinoma Treatment and Prognosis
- Pregnancy and preeclampsia studies
- Cancer Immunotherapy and Biomarkers
- Liver Disease Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Sarcoma Diagnosis and Treatment
- Metastasis and carcinoma case studies
- TGF-β signaling in diseases
- Liver physiology and pathology
- Autophagy in Disease and Therapy
- Heavy Metal Exposure and Toxicity
- Abdominal Surgery and Complications
- Thyroid Cancer Diagnosis and Treatment
- Male Reproductive Health Studies
- Emergency and Acute Care Studies
- Endometrial and Cervical Cancer Treatments
- Wnt/β-catenin signaling in development and cancer
- Maternal and Perinatal Health Interventions
- Chronic Kidney Disease and Diabetes
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Circular RNAs in diseases
- Uterine Myomas and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Phytoestrogen effects and research
- Radiology practices and education
Hebei General Hospital
2024-2025
Beijing Academy of Artificial Intelligence
2024
Gansu Provincial Maternal and Child Health Hospital
2006-2024
Ningxia Medical University
2024
Fudan University
2024
Massachusetts Institute of Technology
2024
Beijing Ditan Hospital
2023
Capital Medical University
2023
Daping Hospital
2022
Army Medical University
2022
To the best of our knowledge, microRNA (miR/miRNA) expression profile plasma exosomes in ovarian cancer has not been previously studied. The aim present study was to investigate practicality using exosomal miRNAs as novel serological biomarkers cancer. In study, exosome‑like vesicles were purified from patients with and healthy women differential centrifugation. vesicles, ranging 50‑100 nm size, identified by transmission electron microscopy western blotting. High‑throughput sequencing...
<title>Abstract</title> [<bold>Objective:</bold>]The purpose of this research was to evaluate the feasibility and efficacy 125I seed brachytherapy for recurrent refractory differentiated thyroid cancers. [<bold>Methods</bold>]:Between August 2005 March 2023 33 patients with recurrence cancer were treated brachytherapy. seeds implanted into tumor under guidance CT and/or 3D-printed template images median prescription dose 126 Gy (range, 90-155 Gy). The number 54 (range 8-214). Clinical...
Bone morphogenetic protein receptor type IB (BMPRIB) is one osteogenesis factor, which function in breast cancer has been rarely explored until recently. In the clinical study presented here, involving a cohort of 368 invasive ductal carcinoma (IDC) patients, we identified that patients with low expression BMPRIB exhibited poor prognosis, especially luminal B subtype. We also provided first piece evidence level was promoting factor for to develop bone metastasis, but not lung, liver or...
Although illness severity scoring systems are widely used to support clinical decision-making and assess ICU performance, their potential bias across different age, sex, primary language groups has not been well-studied.
Neutrophil gelatinase‑associated lipocalin (NGAL), also called 2, is considered a promising biomarker for acute and chronic kidney injuries. Several studies have demonstrated that its levels increase in plasma urine diabetic nephropathy (DN), concentration increases upon function deterioration. However, role DN progression remains unclear. The current study used <em>in vitro</em> gene expression knockdown human proximal tubular cell line (HK)2 to investigate the of NGAL oxidation...
Abstract Objective To investigate the potential of employing sublingual microcirculation as an early noninvasive screening technique for diabetic nephropathy (DN). Research design and methods We recruited 89 patients with type 2 diabetes mellitus (T2DM) 41 healthy subjects in this cross-sectional observational study. All participants underwent fluorescein fundus angiography, vibration perception testing, 10 g (Semmes–Weinstein) monofilament examination, nerve conduction velocity, 24-h urine...
Objective To investigate the effects of AMPK activation on mitochondrial inhibition by uremic serum through AMPK-activated rat peritoneal macrophages stimulated serum, thereby providing a reference for clinical treatment chronic kidney disease. Methods Twenty-two male Sprague-Dawley (SD) rats were included as experimental subjects. Fifteen constructed into disease models (the model group). The remaining seven only received renal capsule stripping instead nephrectomy sham-operated Ten weeks...
Abstract Objective To investigate the efficacy of 125 I seed brachytherapy for non-central pelvic recurrence cervical cancer after external beam radiotherapy, and to analyze clinical influential factors. Methods Between June 2015 April 2022, 32 patients with 41 lesions were treated brachytherapy. The seeds implanted under guidance CT and/or 3D-printed template images at a median dose 100 Gy (range, 80–120 Gy), local control rate (LCR) survival rates calculated. We used multivariate logistic...
Acute mesenteric ischemia (AMI) is insidious in the early stage of disease, and once reaches late stage, irreversible intestinal necrosis even multiple system organ failure occur, ultimately leading to death. Early diagnosis intervention are key improving outcome AMI. Intensive care unit (ICU) patients mostly present with non-occlusive (NOMI) due hypoperfusion. This article reviews high risk factors, clinical manifestations, biomarkers, imaging examinations AMI order provide ideas for...
Pulmonary sarcomatoid carcinoma (PSC), which is a type of non-small-cell lung (NSCLC), characterized by high degree malignancy, poor differentiation and incidence pulmonary malignancy. In addition, PSC has stronger invasive ability than other types NSCLC not sensitive to radiation or chemotherapy. Furthermore, 90% cases exhibit vascular invasion; therefore, there risk multiple metastases the lung, bone, adrenal glands brain, consequently prognosis, in early stage. Targeted therapy...
A growing number of studies suggest that isoflavones found in soybeans have estrogenic activity and may safely alleviate the symptoms menopause. One these isoflavones, genistein, is commonly used by postmenopausal women as an alternative to hormone replacement therapy. Although sex hormones been implicated important risk factor for development hepatocellular carcinoma, there are limited data on potential effects estrogens, including phytoestrogens, chemical mutagenesis liver. Because...
<div>Abstract<p>A number of staging systems have been developed to predict clinical outcomes in hepatocellular carcinoma (HCC). However, no general consensus has reached regarding the optimal model. New approaches such as machine learning (ML) strategies are powerful tools for incorporating risk factors from multiple platforms. We retrospectively reviewed baseline information, including clinicopathologic characteristics, laboratory parameters, and peripheral immune features...
<div>Abstract<p>A number of staging systems have been developed to predict clinical outcomes in hepatocellular carcinoma (HCC). However, no general consensus has reached regarding the optimal model. New approaches such as machine learning (ML) strategies are powerful tools for incorporating risk factors from multiple platforms. We retrospectively reviewed baseline information, including clinicopathologic characteristics, laboratory parameters, and peripheral immune features...