- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Diabetes Management and Research
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- COVID-19 Clinical Research Studies
- Poisoning and overdose treatments
- Nosocomial Infections in ICU
- Cardiac Arrest and Resuscitation
- Anesthesia and Sedative Agents
- Antibiotics Pharmacokinetics and Efficacy
- Pneumocystis jirovecii pneumonia detection and treatment
- Eosinophilic Esophagitis
- Vibrio bacteria research studies
- Anesthesia and Pain Management
- Galectins and Cancer Biology
- Electrolyte and hormonal disorders
- Antibiotic Resistance in Bacteria
- Cardiovascular and exercise physiology
- Neonatal Respiratory Health Research
- Metabolism, Diabetes, and Cancer
- Nausea and vomiting management
Deventer Ziekenhuis
2010-2024
Radboud University Nijmegen
2024
Radboud University Medical Center
2024
Royal Adelaide Hospital
2007
Groene Hart Ziekenhuis
1998
Maastricht University Medical Centre
1993
The USCOM (Ultrasonic Cardiac Output Monitors) device is a noninvasive cardiac output monitor, which utilises transaortic or transpulmonary Doppler flow tracing and valve area estimated using patient height to determine output. We evaluated against thermodilution outputs transoesophageal echocardiography measurements in 22 ASA PS4 surgical patients. Data collection commenced following pulmonary artery catheter insertion, with repeated after sternotomy closure. Failure obtain readings...
For surgical procedures of the upper extremities, brachial plexus block is a suitable technique and offers several advantages for patient, surgeon, anesthesiologist (1). The can be performed at sites, but most frequently used are axillary, interscalene, infraclavicular, supraclavicular approaches (2). Pippa et al. (3) described an alternative, posterior approach to with similar field analgesia. In this article, we report patient who developed life-threatening paralysis without loss...
Background: Pulmonary superinfections with Herpesviridae and Aspergillus spp. are common in severe coronavirus disease 2019 (COVID-19) pneumonia but their epidemiology impact remain poorly understood. Methods: We conducted a retrospective observational study of 61 mechanically ventilated COVID-19 patients at Deventer Hospital’s ICU (2020–2021) who underwent bronchoalveolar lavage (BL) due to clinical deterioration. analyzed blood respiratory samples, treatment, outcomes. Results: Among BL,...
The aim of this study was to investigate the population pharmacokinetics (PK) clonidine in intensive care unit (ICU) patients order develop a dosing regimen for sedation.We included 24 adult mechanically ventilated, sedated from mixed medical and surgical ICU. Intravenous added standard sedation doses 600, 1200 or 1800 μg/d. Within each treatment group, 4 received loading dose half daily administered hours. Patients gave an average 12 samples per individual. In total, 286 were available...
Nine-panel plots are standard displays of cardiopulmonary exercise data, used in cardiac and pulmonary medicine to investigate the nature limitation. We explored whether this approach could be analyze data critically ill patients on mechanical ventilation, capable exercising actively. Patients followed an incremental protocol using a bedside cycle ergometer. Respiratory gases were analyzed indirect calorimetry, blood sampled from arterial catheters. Data seven combined into nine-panel plots....
In Brief We used Orthogonal Polarization Spectral Imaging to examine the microcirculation of vaginal mucosa in nine anesthetized patients during two consecutive anesthetic interventions: hypervolemic hemodilution using hydroxyethyl starch followed by thoracic epidural lidocaine. Images taken before and after each intervention were compared. During hemodilution, systolic blood pressures increased significantly, but functional capillary density remained unchanged. Epidural anesthesia decreased...
COBRA was developed as a decision rule to predict which patients visiting the emergency department (ED) following intentional drug overdose will not require intensive care unit (ICU) interventions. uses parameters from five vital systems (cardiac conduction, oxygenation, blood pressure, respiration, and awareness) that are readily available in ED. recommends against ICU admission when all these normal.The primary aim of this study determine negative predictive value (NPV) predicting...
<b><i>Background:</i></b> Clonidine is an α<sub>2</sub>-agonist that commonly used for sedation in the intensive care unit. When patients are on continuous venovenous hemofiltration (CVVH) presence of kidney dysfunction, sieving coefficient clonidine required to estimate how much drug removed by CVVH. In present study, we measured critically ill, ventilated receiving <b><i>Methods:</i></b> A total 20 samples plasma and ultrafiltrate...
The value of D-dimer assessments in ICU patients with COVID-19 for the prediction pulmonary embolism (PE) is unclear. present study had two purposes: 1. To assess specificity elevated absolute values PE on admission to ICU. 2. a increment development during an stay. were paired results CT angiogram (CTPA) and compared without admission. In initial imaging available repeat CTPA stay, increments between developing stay those persistently no PE. On admission, D-dimers higher than (median 850...
Intensive insulin therapy (IIT) is a complex intervention involving several steps that may all contain potential sources of variability. Changing practice in multidisciplinary environments difficult. In addition, it undecided whether IIT should be applied by nurses and physicians, or alone. We implemented using conceptual implementation framework compared overall blood glucose control incidence severe hypoglycemia (SH) (blood level (BGL) <40 mg/dl) before after implementation.