A5100600675- Lung Cancer Treatments and Mutations
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Misinformation and Its Impacts
- Asthma and respiratory diseases
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Cancer Genomics and Diagnostics
- Colorectal Cancer Treatments and Studies
- Nanoplatforms for cancer theranostics
- HER2/EGFR in Cancer Research
- Global Trade and Competitiveness
- Pediatric health and respiratory diseases
- COVID-19 and Mental Health
- Decision-Making and Behavioral Economics
- Advanced MRI Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- RNA modifications and cancer
- Long-Term Effects of COVID-19
- International Maritime Law Issues
- COVID-19 diagnosis using AI
- Rural development and sustainability
- Video Coding and Compression Technologies
- Land Use and Ecosystem Services
- Photodynamic Therapy Research Studies
Kunming Medical University
2024
Sichuan University
2021-2024
West China Hospital of Sichuan University
2021-2024
Dalian Maritime University
2024
Anhui University
2024
Shanghai Jiao Tong University
2008-2023
XinHua Hospital
2011-2023
Fuzhou University
2017-2023
Tongji University
2022-2023
Northwest Normal University
2014-2023
Abstract During global pandemics, such as coronavirus disease 2019 (COVID-19), crisis communication is indispensable in dispelling fears, uncertainty, and unifying individuals worldwide a collective fight against health threats. Inadequate can bring dire personal economic consequences. Mounting research shows that seemingly endless newsfeeds related to COVID-19 infection death rates could considerably increase the risk of mental problems. Unfortunately, media reports include infodemics...
Abstract Background Since December 2019, the outbreak of COVID-19 caused a large number hospital admissions in China. Many patients with have symptoms acute respiratory distress syndrome, even are danger death. This is first study to evaluate dynamic changes D-Dimer and Neutrophil-Lymphocyte Count Ratio (NLR) as prognostic utility for clinical use. Methods In retrospective study, we collected data from 349 hospitalized who diagnosed infection Wuhan Pulmonary Hospital. We used ROC curves Cox...
In December 2019, pneumonia cases of unknown origin were reported in Wuhan City, Hubei Province, China. Identified as the coronavirus disease (COVID-19), number grew rapidly by human-to-human transmission Wuhan. Social media, especially Sina Weibo (a major Chinese microblogging social media site), has become an important platform for public to obtain information and seek help.This study aims analyze characteristics suspected or laboratory-confirmed COVID-19 patients who asked help on...
Previous studies revealed that both self-concept and social support were associated with mental health in college students. Very few have explored the ways these two variables work on health, particularly mainland China. In present study, 411 students northwest China assessed using School Society Situations Scale (which includes a sub-scale sub-scale) Self-report Symptom Checklist 90. The results showed positive was positively correlated individual perceived from parents, teachers, peers,...
### Summary box In many areas of the world, phrases such as ‘Wuhan virus’, ‘China virus’ and ‘Chinese have been frequently used by laypeople, influential politicians mass media to refer virus SARS-CoV-2 that caused COVID-19 pandemic.1 Naming a after geographic location or group people is not unheard-of, for example, Middle East respiratory syndrome (MERS) Legionnaires’ disease.2 However, having precedence de facto justification using these alternatives, mentioned above, SARS-CoV-2....
Background: COVID-19 has been quickly spreading, making it a serious public health threat. It is important to identify phenotypes predict the severity of disease and design an individualized treatment. Methods: We collected data from 213 patients in Wuhan Pulmonary Hospital January 1 March 30, 2020. Principal component analysis (PCA) cluster were used classify patients. Results: identified three distinct subgroups COVID-19. Cluster was largest group (52.6%) characterized by oldest age,...
Abstract Objective: Osimertinib is the 3rd generation EGFR inhibitor, which has been approved for treatment of NSCLC patients with EGFRT790M. More recently, a tertiary EGFRC797S mutation was reported as dominant resistance (40~20%) mechanism to Osimertinib. The emergence C797S prevent covalent bond formation Osimertinib, and caused drug resistance. So, it’s an urgent demand new inhibitors that can effectively inhibit triple mutant, d746-750/T790M/C797S & L858R/T790M/C797S. Here, we...
To explore the value of machine learning model based on CE-MRI radiomic features in preoperative prediction sentinel lymph node (SLN) metastasis breast cancer.The clinical, pathological and MRI data 177 patients with pathologically confirmed cancer (81 SLN positive 96 negative) underwent conventional DCE-MRI before surgery First Affiliated Hospital Soochow University from January 2015 to May 2021 were analyzed retrospectively. The samples randomly divided into training set (n=123) validation...
Abstract Background Atopic dermatitis (AD) is a chronic relapsing inflammatory skin disease. There have been few detailed reports of the clinical evaluation Chinese patients with AD. Objectives To give profile features AD in university hospital setting. Methods A total 1008 cases met Hanifin and Rajka diagnostic criteria were recruited at Xinhua Hospital, Shanghai Jiaotong University School Medicine, China. Results In our survey, 22.7% mild, 66.6% moderate 10.7% severe according to SCORAD...
Objectives This study aimed to examine the coverage of coronavirus disease 2019 (COVID-19) vaccination and its cognitive determinants among older adults. Methods A cross-sectional was conducted using a questionnaire conduct survey 725 Chinese adults aged 60 years above in June 2022, 2 months after mass COVID-19 outbreak Shanghai, China. The covered demographic characteristics, status, internal risk perception, knowledge, attitude toward efficacy safety vaccines. Results rate 78.3% surveyed...
Objective: Atherosclerosis involves endothelial injury caused by oxidative stress. Endothelial progenitor cells (EPCs) play important roles in preventing the early stages of atherosclerosis. Meanwhile, poly (ADP-ribose) polymerase 1 (PARP1) utilizes nicotinamide adenine dinucleotide (NAD+) to repair DNA damage. PARP1 overactivation results excessive NAD+ consumption presence pathological PJ34 is a inhibitor that attenuates cellular depletion and can prevent dysfunction. However, few studies...
Paclitaxel (PTX) is a widely used anticancer drug that works by inhibiting microtubule disassembly. PTX safety was greatly enhanced embedding it with human albumin. Here, we study the synergistic effects of photodynamic therapy (PDT) both in vitro and vivo constructing photosensitizer–PTX nanotheranostics (PPNTs). PPNTs were fabricated via noncovalent hydrophobic interactions π–π stacking between an amphipathic photosensitizer average diameter ∼80 nm, these showed high stability biological...
Since the outbreak of COVID-19 epidemic, it has spread on a large scale around world, seriously affecting people's physical and mental health. In China, almost all schools have postponed semesters, suspended offline classes, implemented closed-off management, which brought significant challenges to study life college students. The aimed explore relationship between risk perception, perceived stress, control, health among Chinese This cross-sectional was conducted 1,856 results showed that...
We demonstrate that physiologically relevant perturbations in the osmotic environment rheostatically regulate a gatekeeping function for nucleolus controls spatial dynamics and functions of nucleolin. HeLa cells U2-OS osteosarcoma were osmotically challenged with 100-200 mm sorbitol, intranuclear distribution nucleolin was monitored by confocal microscopy. Nucleolin normally resides innermost fibrillar core nucleolus, where it assists rDNA transcription replication, expelled within 30 min...
Cancer is the leading cause of death worldwide. Tobacco smoking, including secondhand causes cancer and responsible for over 22% global deaths. The adverse impacts smoke are more pronounced expectant mothers, can deteriorate both mothers’ infants’ health well-being. Research suggests that significantly increases risk miscarriage, cancer, other chronic disease conditions, exposes their unborn babies to an increased likelihood having life-long poor health. In China, a pregnant woman’s family...
Acculturation could cause grave health consequences in international students. However, there is a shortage of research into how acculturative stress might affect students' quality life light their academic standing and experience. The lack particularly pronounced among Chinese students, representing the largest body students studying United States (U.S.). Thus, to bridge gap, this study aims examine interplay between stress, standing, nationally representative sample States.An online survey...
Background Lung cancer is a leading cause of death worldwide, and its incidence shows an upward trend. A study the long-term changes in premature rate lung developed region China has great exploratory significance to further clarify effectiveness intervention measures. Objective This examined rates order understand mortality design future prevention plans Pudong New Area (PNA), Shanghai, China. Methods Cancer data were collected from Mortality Registration System PNA. We analyzed crude...