A5046731453- Extraction and Separation Processes
- Recycling and Waste Management Techniques
- Healthcare Systems and Reforms
- Nanoplatforms for cancer theranostics
- Environmental Impact and Sustainability
- Photodynamic Therapy Research Studies
- Catalysis for Biomass Conversion
- Cancer, Hypoxia, and Metabolism
- Lignin and Wood Chemistry
- Catalysis and Hydrodesulfurization Studies
- Prostate Cancer Treatment and Research
- Cancer, Lipids, and Metabolism
- Global Health Care Issues
- Healthcare Policy and Management
- Luminescence Properties of Advanced Materials
- Advancements in Battery Materials
- Metal Extraction and Bioleaching
- Angiogenesis and VEGF in Cancer
- Luminescence and Fluorescent Materials
- Carbon Dioxide Capture Technologies
- Metabolomics and Mass Spectrometry Studies
- Advanced Battery Technologies Research
- RNA modifications and cancer
- Health disparities and outcomes
- Sulfur Compounds in Biology
Roswell Park Comprehensive Cancer Center
2020-2025
The University of Texas Southwestern Medical Center
2025
Southwestern Medical Center
2025
Hunan Cancer Hospital
2018-2024
Central South University
2018-2024
Beijing Institute of Geology for Mineral Resources
2017-2024
Chinese Academy of Geological Sciences
2017-2024
China Geological Survey
2020-2024
Quanzhou Normal University
2024
Tongji University
2024
In recent years, increasing attention has been given to the potential supply risks of critical battery materials, such as cobalt, for electric mobility transitions. While technology and recycling advancement are two widely acknowledged strategies addressing risks, extent which they will relieve global regional cobalt demand-supply imbalance remains poorly understood. Here, we address this gap by simulating historical (1998-2019) future (2020-2050) cycles covering both traditional emerging...
Stromal cell-derived factor (SDF)-1α, a member of the chemokine CXC subfamily, plays an important role in regulation variety cellular functions endothelial progenitor cells such as cell migration, proliferation, survival and angiogenesis. However, there is relatively little information linking individual signaling pathways mediated by SDF-1α cells. In our study, we showed that expressed CXCR4 reverse transcription polymerase chain reaction flow cytometric analysis. Functional analysis...
Lignins isolated from representative hardwood, softwood, and grass materials were effectively hydrocracked to aromatics catalyzed by tungsten carbide over activated carbon (W2 C/AC). The effects of botanical species fractionation methods on lignin structure the activity W2 C/AC studied in detail. Gas permeation chromatography (GPC), FTIR, elemental analysis, 2 D HSQC NMR showed that all extracted samples shared basic skeleton lignin, whereas method significantly affected structure....
The rapid emergence of drug-resistant bacteria has raised a great social concern together with the impetus for exploring advanced antibacterial ways. NIR-triggered antimicrobial photodynamic therapy (PDT) by lanthanide-doped upconversion nanoparticles (UCNP) as energy donor exhibits advantages high tissue penetration, broad spectrum and less acquired resistance, but is still limited its low efficacy. Now we designed bio-inorganic nanohybrid combined lysozyme (LYZ) UCNP-PDT system to enhance...
Abstract Triple negative breast cancer (TNBC) is one of the deadliest subtypes cancer, whose high frequency relapse often due to resistance chemotherapy. Here, we identify inosine monophosphate dehydrogenase 2 (IMPDH2) as a contributor doxorubicin resistance, in multiple TNBC models. Analysis publicly available datasets reveals elevated IMPDH2 expression associate with worse overall prognosis clinic, including lower recurrence-free survival post adjuvant/neoadjuvant therapy. Importantly,...
Rationale: Twist is a key transcription factor for induction of epithelial-mesenchymal transition (EMT), which promotes cell migration, invasion, and cancer metastasis, confers cells with stem cell-like characteristics, provides therapeutic resistance. However, the functional roles targeted genes in EMT progression remain elusive. Methods: The potential were identified from global transcriptomes T47D/Twist by microarray analysis. phenotype was detected western blotting immunofluorescence...
Abstract A remarkably effective method for the chemoselective cleavage of C−O bonds typical β‐O‐4 model compounds and deconstruction lignin feedstock was developed by using tungsten carbide as catalyst. High yields products (up to 96.8 %) from liquid oils 70.7 were obtained under low hydrogen pressure (0.69 MPa) in methanol. The conversion efficiency determined a large extent solvent effects also affected both electronic steric compounds. In situ W 2 C/activated carbon (AC)‐catalyzed...
The rapid urbanization in China since the 1970s has led to an exponential growth of metal stocks (MS) use cities. A retrospect on quantity, quality, and patterns these MS is a prerequisite for projecting future demand, identifying urban mining potentials metals, informing sustainable strategies. Here, we deployed bottom-up stock accounting method estimate iron, copper, aluminum embodied 51 categories products infrastructure across 10 Chinese megacities from 1980 2016. We found that had...
Abstract Tungsten‐based bimetallic catalysts M–W/AC (M=Ru, Pt, and Pd; AC=activated carbon) exhibited high activity selectivity in the hydrogenolysis of typical α‐O‐4 model compounds deconstruction lignin feedstock for production aromatic chemicals. Synergy effect was observed between tungsten noble‐metal species, which on one hand modulated improved catalyst, other suppressed overhydrogenation that avoided formation cycloalkanes. The conversion with different substituents showed electronic...
Database management systems (DBMSs) have a plethora of tunable knobs that control almost everything in the system. The performance DBMS is highly dependent on these configuration knobs, however, getting this tuning right hard. Many organizations resort to hiring experts configure but prohibitively expensive. As databases grow both size and complexity, optimizing has surpassed abilities even best human experts. We recently introduced OtterTune, service able automatically find good settings...
Metabolic dysregulation is a known hallmark of cancer progression, yet the oncogenic signals that promote metabolic adaptations to drive metastatic remain unclear. Here, we show transcriptional repression mitochondrial deacetylase sirtuin 3 (