- Advanced Chemical Sensor Technologies
- Video Analysis and Summarization
- Music and Audio Processing
- Multimedia Communication and Technology
- Nosocomial Infections in ICU
- Advanced Image and Video Retrieval Techniques
- Metabolomics and Mass Spectrometry Studies
- Asthma and respiratory diseases
- Quantum Chromodynamics and Particle Interactions
- Multiple Sclerosis Research Studies
- Infant Development and Preterm Care
- High-Energy Particle Collisions Research
- Inhalation and Respiratory Drug Delivery
- Respiratory and Cough-Related Research
- Image Retrieval and Classification Techniques
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Olfactory and Sensory Function Studies
- Infant Health and Development
- Superconducting Materials and Applications
- Particle physics theoretical and experimental studies
- Speech and Audio Processing
- Image and Object Detection Techniques
- Image Enhancement Techniques
- Gut microbiota and health
Nederlands Instituut Publieke Veiligheid
2025
Philips (Netherlands)
2006-2019
Philips (United States)
2018
NXP (Netherlands)
2015-2017
Philips (Finland)
2006-2015
Philips (India)
2014
Utrecht University
2002-2005
There is a need for biological markers of the acute respiratory distress syndrome (ARDS). Exhaled breath contains hundreds metabolites in gas phase, some which reflect (patho)physiological processes. We aimed to determine diagnostic accuracy exhaled as biomarkers ARDS. Breath from ventilated intensive care unit patients (n=101) was analysed using chromatography and mass spectrometry during first day admission. ARDS defined by Berlin definition. Training temporal validation cohorts were used....
The diagnosis of ventilator-associated pneumonia (VAP) remains time-consuming and costly, the clinical tools lack specificity a bedside test to exclude infection in suspected patients is unavailable. Breath contains hundreds thousands volatile organic compounds (VOCs) that result from host microbial metabolism as well environment. present study aims use breath VOC analysis develop model can discriminate between who have positive cultures negative with high sensitivity. Molecular Analysis...
The diagnosis of hospital-acquired pneumonia remains challenging. We hypothesized that analysis volatile organic compounds (VOCs) in exhaled breath could be used to diagnose or the presence pathogens respiratory tract intubated and mechanically-ventilated intensive care unit patients. In this prospective, single-centre, cross-sectional cohort study from mechanically ventilated patients was analysed using gas chromatography-mass spectrometry. Potentially relevant VOCs were selected with a...
Abstract Background Ventilator-associated pneumonia (VAP) is associated with high morbidity and health care costs, yet diagnosis remains a challenge. Analysis of airway microbiota by amplicon sequencing provides possible solution, as characterised disruption the microbiome. However, studies evaluating diagnostic capabilities microbiome analysis are limited, lack alignment on biomarkers. Using bronchoalveolar lavage fluid (BALF) from ventilated adult patients suspected VAP, we aimed to...
A large number of videos are captured and shared by the audience from musical concerts. However, such recordings typically perceived as boring mainly because their limited view, poor visual quality incomplete coverage. It is our objective to enrich viewing experience these exploiting abundance content multiple sources. In this paper, we propose a novel \Virtual Director system that automatically combines most desirable segments different resulting in single video stream, called mashup. We...
Alterations in fecal microbiota and volatile organic compound (VOC) profiles of preterm infants have been demonstrated before onset necrotizing enterocolitis (NEC). However, NEC-specific signatures need to be identified potential application as predictive biomarker clinical practice. A prospective multicenter case–control study was conducted identify preclinical VOC that developed NEC. Microbiota analysis (PCR-based IS-pro technique) (gas chromatography-mass spectrometry) were performed on...
Introduction Asthma is a heterogeneous condition, characterised by chronic inflammation of the airways, typically managed with inhaled bronchodilators and corticosteroids. In case uncontrolled asthma, oral corticosteroids (OCSs) are often prescribed. Good adherence inhalation technique associated improved outcomes; however, it difficult to monitor appropriate drug intake effectiveness in individual patients. Exhaled breath contains thousands volatile organic compounds (VOCs) that reflect...
An increasing number of people regularly capture video in social occasions like weddings, parties and holiday trips. As a result, multiple recordings are made from single event providing different view angles wider coverage. This gives an opportunity to produce desired summary the event, combining videos with most favorable views recordings. In order mix contents cameras, require very precise synchronization time. task is tedious presently done manually. We present two methods synchronize...
Digital video capturing is getting popular with the decreasing price of camcorders and increasing availability devices embedded cameras such as digital-still cameras, mobile phones PDAs. While a raw home considered visually non-appealing, having multiple recordings same event provides opportunity to combine audio segments from different for improving quality aesthetics. Mixing content requires precise synchronization among recordings. In most present applications, done manually very tedious...
Bacterial volatile organic compounds have the potential to be utilised as diagnostic biomarkers for infections.
Infections such as ventilator-associated pneumonia (VAP) can be caused by one or more pathogens. Current methods for identifying these pathogenic microbes often require invasive sampling, and time consuming, due to the requirement prolonged cultural enrichment along with selective differential plating steps. This results in delays diagnosis which critically ill patients have potentially life-threatening consequences. Therefore, a non-invasive timely diagnostic method is required. Detection...
Cognitive impairment is frequent in multiple sclerosis (MS), but reliable, sensitive and individualized monitoring clinical practice still limited. Smartphone-adapted tests may enhance the assessment of function as can be performed more frequently within daily living environment. The objectives were to prove reproducibility a smartphone-based Symbol Digit Modalities Test (sSDMT), its responsiveness relevant change cognitive outcomes, develop an individual-based method for cognition.In...
Horizon detection in still images or video sequences contributes to applications like image understanding, automatic correction of tilt and quality enhancement. In this paper, we propose an algorithm for detecting the horizon line digital images, which employs edge-based a new color-based technique. The detector calculates estimate by analyzing color transition clear sky areas image. computes finding most prominent edge image, based on Canny Hough transformation. proposed combines two...
Abstract Background Early and accurate recognition of respiratory pathogens is crucial to prevent increased risk mortality in critically ill patients. Microbial-derived volatile organic compounds (mVOCs) exhaled breath could be used as noninvasive biomarkers infection support clinical diagnosis. Methods In this study, we investigated the diagnostic potential vitro–confirmed mVOCs patients under mechanical ventilation from BreathDx study. Samples were analyzed by thermal desorption–gas...
Combining audiovisual sequences from different cameras requires precise alignment in time. Current synchronization techniques involve using geometrical properties such as camera positions and object features. In this paper, we present a method based on detecting flashes the video content. Such flashes, generated by still cameras, cause sharp bright frame videos. They are detected an adaptive threshold luminance variation across frames. The resulting flash searched for matches. matching...
Methods for breath sampling and analysis require robust quality assessment to minimise the risk of false discoveries. Planning large-scale multi-site metabolite profiling studies also requires careful consideration systematic random variation as a result techniques. In this study we use sample data from recent U-BIOPRED cohort evaluate discuss some important methodological considerations such batch correction, between sites, storage transportation, well inter-instrument analytical...
Abstract Introduction Headspace gas chromatography–mass spectrometry (HS-GC–MS) is widely considered the gold standard of quantitative fecal VOC analysis. However, guidelines providing general recommendations for bioanalytical method application in research and clinical setting are lacking. Objectives To propose an evidence-based protocol analysis by HS-GC–MS, based on extensive testing instrumental sampling conditions detection quantification limits, linearity, accuracy repeatability...
The movie industry produces thousands of feature films and TV series annually. Such massive data volumes would take consumers more than a lifetime to watch. Therefore, summarization narrative media, which engages in providing concise informative video summaries, has become popular topic research. However, most the solutions so far aim represent just overall atmosphere at expense story line. In this paper we describe novel approach for automated creation summaries videos. We propose an...
Patients suspected of ventilator-associated lower respiratory tract infections (VA-LRTIs) commonly receive broad-spectrum antimicrobial therapy unnecessarily. We tested whether exhaled breath analysis can discriminate between patients VA-LRTI with confirmed infection, from negative cultures. Breath 108 was analysed by gas chromatography-mass spectrometry. The test had a sensitivity 98% at specificity 49%, second analytical method. predictive value 96% and excluded pneumonia in half the Trial...
Alkanes and alkenes in the breath are produced through fatty acid peroxidation, which is initialized by reactive oxygen species. Inflammation an important cause effect of We aimed to evaluate association between peroxidation products inflammation alveolar systemic compartment ventilated intensive care unit (ICU) patients.
An effective quark Lagrangian is derived from first principles through bilocal gluon field correlators. It used to write down equations for baryons, containing both perturbative and nonperturbative fields. As a result one obtains magnetic moments of octet decuplet baryons without the introduction constituent masses using only string tension as input. Magnetic come out on average in reasonable agreement with experiment, except nucleons ${\ensuremath{\Sigma}}^{\ensuremath{-}}.$ The predictions...