Lianfu Zhang

ORCID: 0000-0001-6676-5813
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Research Areas
  • Antioxidant Activity and Oxidative Stress
  • Phytochemicals and Antioxidant Activities
  • Proteins in Food Systems
  • Free Radicals and Antioxidants
  • Polysaccharides and Plant Cell Walls
  • Biological and pharmacological studies of plants
  • Microencapsulation and Drying Processes
  • Polysaccharides Composition and Applications
  • Advanced Glycation End Products research
  • Biochemical Analysis and Sensing Techniques
  • Intracranial Aneurysms: Treatment and Complications
  • Edible Oils Quality and Analysis
  • Food composition and properties
  • Cholesterol and Lipid Metabolism
  • Ginseng Biological Effects and Applications
  • Coenzyme Q10 studies and effects
  • Food Quality and Safety Studies
  • Selenium in Biological Systems
  • Vitamin C and Antioxidants Research
  • Pickering emulsions and particle stabilization
  • Essential Oils and Antimicrobial Activity
  • Fungal Biology and Applications
  • Surfactants and Colloidal Systems
  • Tea Polyphenols and Effects
  • Bee Products Chemical Analysis

Jiangnan University
2016-2025

State Key Laboratory of Food Science and Technology
2016-2025

Anhui Provincial Hospital
2023-2025

First Affiliated Hospital of Anhui Medical University
2025

Anhui Medical University
2025

Shandong First Medical University
2023

Creative Commons
2023

State Council of the People's Republic of China
2019-2021

Beijing Technology and Business University
2017-2020

Beijing Advanced Sciences and Innovation Center
2019

The anti-inflammatory effects and cellular transport mechanisms of all-E-astaxanthin its 9Z- 13Z-isomers were investigated in a Caco-2 cell monolayer model. All three astaxanthin isomers at 1.2 μM significantly reduced the TNF-α-induced secretion IL-8 by 22–27%. Z-Astaxanthins, especially 9Z-astaxanthin exhibited greater effect than down-regulating pro-inflammatory cytokines COX-2 TNF-α gene expression to 0.88 ± 0.01-fold 0.83 0.17-fold that negative control (NC), respectively. achieved via...

10.1021/acs.jafc.9b02102 article EN Journal of Agricultural and Food Chemistry 2019-05-22

Abstract As by‐products of grape juice and wine production, seeds are a rich source procyanidins but usually discarded as waste. We have treated with supercritical fluid extraction to remove the oils extracted from residues. In order extend shelf life, micro‐encapsulating methods for were studied: use gum arabic maltodextrin wall materials (the contents 40% 60%, respectively). The raw then mixed ratio core substance material was 30:70 w/w content slurry 20% w/v). After homogenisation, spray...

10.1002/jsfa.2899 article EN Journal of the Science of Food and Agriculture 2007-07-24

An optimized isomerization method was developed by heating all-E-astaxanthin in ethyl acetate (70 °C) with I-TiO2 catalyst, yielding 22.7% and 16.9% of 9Z- 13Z-astaxanthin, respectively, 2 h, 92-95% purity after semipreparative HPLC purification. 13Z-Astaxanthin had higher antioxidant activity than all-E- 9Z-astaxanthins oxygen radical absorbing capacity assay for lipophilic compounds, photochemiluminescence, cellular (CAA) assays, 9Z-astaxanthin DPPH radical-scavenging lower CAA assay. All...

10.1021/acs.jafc.6b04962 article EN Journal of Agricultural and Food Chemistry 2017-01-10

The bioaccessibility, bioavailability, and antioxidative activities of three astaxanthin geometric isomers were investigated using an in vitro digestion model human intestinal Caco-2 cells. This study demonstrated that the trans-cis isomerization all-E-astaxanthin cis-trans Z-astaxanthins could happen both during gastrointestinal cellular uptake processes. 13Z-Astaxanthin showed higher bioaccessibility than 9Z- all-E-astaxanthins digestion, 9Z-astaxanthin exhibited transport efficiency...

10.1021/acs.jafc.7b04254 article EN Journal of Agricultural and Food Chemistry 2017-10-30

This study aims to investigate the effects of preoperative intracerebral hematoma volume (HVpre), 6-8 days post-surgery (HVpost), and rate change (HVpre-HVpost)/HVpre on prognosis patients with aneurysmal subarachnoid hemorrhage (aSAH). CT imaging data from 62 aSAH admitted our hospital's Neurosurgery Department between January 2022 December 2023 were obtained, both preoperatively postoperatively. The volumes measured using 3D-Slicer. Patients' recovery at 3 months post-discharge was...

10.3389/fneur.2024.1490957 article EN cc-by Frontiers in Neurology 2025-01-08

Abstract BACKGROUND During vegetable cooking, one of the most notable and common chemical reactions is Maillard reaction, which occurs as a result thermal treatment dehydration. Amadori compound determination provides very sensitive indicator for early detection quality changes caused by well to retrospectively assess heat or storage conditions product has been subjected. In this paper, hydrophilic interaction liquid chromatographic–electrospray ionization–tandem mass spectrometric method...

10.1002/jsfa.8455 article EN Journal of the Science of Food and Agriculture 2017-06-02

Lycopene cis-isomers have shown to be more bioavailable and bioactive than the naturally occurring all-trans-isomer. During food processing, lycopene undergoes geometrical isomerization, increasing proportion of cis-isomers. However, tends retro-isomerize during storage. Because stability, bioavailability, distribution isomers are physiochemical characteristics critical for health benefits, it is essential preserve these properties in products containing isomers. The objective this article...

10.1080/87559129.2011.563392 article EN Food Reviews International 2011-02-23

Abstract In herbal markets, an overwhelming majority the D. officinale are sold in spiral or spring form, and this kind of product would lead to incomplete release some nutrients. To increase bioaccessibility , we report a method pulverisation treatments including general superfine grinding reduce particle size. comparison with coarse ground sizes <18 μm resulted significant higher bulk density, better flowability greater hydration properties. The protein polysaccharide solubility...

10.1111/ijfs.13405 article EN International Journal of Food Science & Technology 2017-04-10

Abstract Highly efficient heterogeneous catalytic E / Z isomerization of lycopene was achieved using an iodine‐doped titanium dioxide (I‐TiO 2 ) catalyst prepared by sol‐gel method. The effects reaction temperature and time were investigated in detail. maximum total ‐ratio exceeded 78% after h refluxing at 75 °C ethyl acetate. Moreover, samples with a series ‐ratios the bioaccessibility these estimated diffusion model, results showed that markedly increased conforming to linear regression...

10.1111/1750-3841.13419 article EN Journal of Food Science 2016-09-07

Abstract The effects of superfine grinding on the physicochemical and functional properties asparagus pomace were investigated. results showed that in terms specific surface area, water solubility, soluble dietary fiber content, ratio insoluble to fiber, finer samples usually possessed better compared with coarse samples. However, excessively produce small particle sizes could reduce water‐holding capacity, oil‐binding swelling capacity. In addition, extraction both free bound phenolics...

10.1111/1750-3841.15168 article EN Journal of Food Science 2020-05-31

Onion and EVOO promoted lycopene isomerization bioaccessibility during heating tomato–onion–EVOO based sauces using a D-optimal mixture design method.

10.1039/c9fo00208a article EN Food & Function 2019-01-01
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