A5101932590- Reproductive Biology and Fertility
- Ovarian function and disorders
- Sperm and Testicular Function
- Cardiac Ischemia and Reperfusion
- Anesthesia and Neurotoxicity Research
- Advanced Nanomaterials in Catalysis
- Nanocluster Synthesis and Applications
- Anesthesia and Pain Management
- Sepsis Diagnosis and Treatment
- Selenium in Biological Systems
- Effects and risks of endocrine disrupting chemicals
- Nanoparticles: synthesis and applications
- Immune Response and Inflammation
- Neurological Disease Mechanisms and Treatments
- Organ Transplantation Techniques and Outcomes
- Acute Kidney Injury Research
- Pluripotent Stem Cells Research
- Circadian rhythm and melatonin
- nanoparticles nucleation surface interactions
University of Saskatchewan
2022-2023
Tehran University of Medical Sciences
2011-2020
University of Tehran
2016
Ovarian tissue cryopreservation together with follicle culture provides a promising technique for fertility preservation in cancer patients. The study aimed to evaluate parameters medium supplemented VEGFA165 and/or fetuin. Vitrified-warmed ovarian cortical pieces were divided randomly into four groups consisting of basic (control), and the VEGFA165, fetuin or both. After six days culture, we evaluated following: percentage resting, primary secondary growing follicles; survival rate; steroid...
Ovarian tissue cryopreservation transplantation (OTCT) is the most flexible option to preserve fertility in women and children with cancer. However, OTCT associated follicle loss an accompanying short lifespan of grafts. Cryopreservation-induced damage could be due cryoprotective agent (CPA) toxicity osmotic shock. Therefore, one way avoid this maintain cell volume within tolerance limits (OTLs). Here, we aimed determine, for first time, OTLs ovarian stromal cells (OSCs) their relationship...
Oxidative stress has negative impacts on the clinical outcomes of assisted reproduction techniques. The brain-derived neurotrophic factor (BDNF) promotes viability nerve cells and is known to decrease oxidative apoptosis in different cells. aim this study was evaluate effect BDNF treatment human sperm functions that are be essential for fertilisation. Our findings showed spermatozoa with 0.133 nM significantly increased percentages both total (P = 0.001) progressive < 0.01) motile compared...
Abstract Oncology treatments cause infertility, and ovarian tissue cryopreservation transplantation (OTCT) is the only option for fertility preservation in prepubertal girls with cancer. However, OTCT associated massive follicle loss. Here, we aimed to determine effect of supplementation slow freezing vitrification media BAPTA-AM melatonin alone combination on viability, reactive oxygen species (ROS) levels, total antioxidant capacity (TAC), follicular morphology viability. Our results...
Teratoasthenozoospermia (TA) is a severe form of male infertility with no clear etiology.To compare the level intracellular anion superoxide (O2-), heat shock protein A2 (HSPA2) and protamine deficiencies in ejaculated spermatozoa between teratoasthenozoospermic normozoospermic men.In this case- control study, semen samples 20 infertile men, TA (with normal morphology lower than 4%_ total motility 40% ) as case group fertile men were evaluated for O2- HSPA2 by flow cytometry deficiency...
The neurotrophin family of proteins and their receptors act as important proliferative pro-survival factors in differentiation nerve cells are thought to play key roles the development reproductive tissues normal function spermatozoa. objective present study was evaluate effect Brain-Derived Neurotrophic Factor (BDNF) on sperm viability motility, lipid peroxidation (LPO), mitochondrial activity concentration leptin, nitric oxide (NO) insulin normozoospermic men. Semen samples from 20 men...
Induction of septic shock by lipopolysaccharide (LPS) may lead to acute renal failure. The present study aimed investigate the impact sex differences on effectiveness low-dose LPS preconditioning (LPS-PC) LPS-induced failure in rats.This was conducted at Tehran University Medical Sciences, 2017. A total 48 Wistar rats were equally divided into two groups male and female rats. each group then allocated three (n=8 per group), namely control, shock, LPS-PC group. high dose administered for...