A5081947167- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Lymphatic System and Diseases
- Cancer-related cognitive impairment studies
- Breast Cancer Treatment Studies
- Family Support in Illness
- Chemotherapy-induced cardiotoxicity and mitigation
- BRCA gene mutations in cancer
- Diagnosis and Treatment of Venous Diseases
- Medication Adherence and Compliance
- Multiple and Secondary Primary Cancers
- Cancer Treatment and Pharmacology
- Acute Lymphoblastic Leukemia research
- Gun Ownership and Violence Research
- Cancer Genomics and Diagnostics
- Menopause: Health Impacts and Treatments
- Urticaria and Related Conditions
- Global Cancer Incidence and Screening
- Glioma Diagnosis and Treatment
- Vietnamese History and Culture Studies
- Crime Patterns and Interventions
- Reproductive System and Pregnancy
- Reproductive Health and Contraception
- Suicide and Self-Harm Studies
- Demographic Trends and Gender Preferences
Karolinska Institutet
2015-2024
Swedish Council on Technology Assessment in Health Care
2024
Stockholm South General Hospital
2008-2022
Karolinska University Hospital
2007-2020
The most common female cancer in Western countries is breast and women diagnosed with this disease are often under 65 years old. With increasing prevalence of survivors it important to shed light on problems facing these after diagnosis treatment. aim study was assess factors predicting return work (RTW) early-stage cancer.A cohort 102 aged 18-64 who had undergone curative primary surgery or without systemic adjuvant therapy were followed for 10 months using data from questionnaires medical...
JOHNSSON A., FORNANDER T., RUTQVIST L.E. & OLSSON M. (2010) European Journal of Cancer Care19, 317–323Factors influencing return to work: a narrative study women treated for breast cancer The purpose this qualitative was identify factors contributing successful the labour market after treatment from women's own perspective. is based on 16 narratives – open-ended, in-depth interviews about experiences and thoughts period surgery when they focused their work. were recruited participants...
Relatively few studies have addressed problems regarding return to work after primary treatment for early-stage breast cancer. The purpose of this study was investigate whether socio-economic and treatment-related factors were associated with returning among pre-menopausal women included in a randomized trial adjuvant endocrine therapy. duration all treatments the two years. At 24 months randomization 35 222 recurrence-free patients (16%) had not returned work. use therapy twofold increase...
The aims of this study were to generate new knowledge about factors predicting return work (RTW) among women treated for early-stage breast cancer, and changes in life satisfaction, coping, examine the association between these concepts RTW.A cohort 102 aged 18-64 assessed six weeks, months, ten months after surgery using data from questionnaires medical files.Factors independently no RTW at were: chemotherapy, > 30 days sick leave during previous 12 low satisfaction with activities daily...
Scand J Caring Sci; 2013; 27; 380–387 Cognitive, psychosocial, somatic and treatment factors predicting return to work after breast cancer Background: Breast (BC) may affect the ability work. In this study, we want identify any associations between cognitive, with time (RTW) among women treated for BC. Methods participants: At eight (baseline) 11(follow‐up) months BC diagnosis, who had received adjuvant early at Stockholm South General Hospital completed Headminder neuropsychological tests...
Introduction Lymphoedema may cause complex problems that can strongly influence patients' health‐related quality of life ( HRQ oL). The main purpose this study was to investigate the impact lymphoedema on oL in patients with varying forms lymphoedema. Methods Quality Life Inventory (Ly QLI ), measuring three domains, physical, psychosocial and practical, Short Form 36 Health Survey Questionnaire SF ‐36), eight health were sent 200 patients. Out those who answered both questionnaires, 88 had...
Women with a newly diagnosed hormone receptor-positive breast cancer are offered adjuvant endocrine therapy (AET). Although the treatment reduces risk of relapse and death not all women adherent to it. Many factors, including therapy's menopausal side effects, can adversely affect adherence treatment. This study explores extent which treated AET perceived that health care providers addressed their effects.Ten focus groups were set up, containing between four nine women. In total, 58...
Lymphedema may affect patients' health-related quality of life (HRQoL) and thus a disease-specific questionnaire is needed. The Quality Inventory (LyQLI) has been tested for reliability validity. purpose this study was to test the LyQLI responsiveness sensitivity.The participants were patients with lymphedema in upper or lower limb, attending Swedish rehabilitation program (RP) undergoing conservative treatment without surgery (RP-sample), liposuction (LS) Australia, Scotland, Sweden...
Background: Lymphedema may impact patients' health-related quality of life (HRQoL). The purpose this study was to evaluate HRQoL after two different treatments the 12-month follow-up point. Methods and Results: Study participants were patients with moderate lymphedema in upper or lower limb who attended a Swedish rehabilitation program (RP) undergoing conservative treatment, those severe, chronic dominated by excess adipose tissue, underwent liposuction (LS) combined controlled compression...
Abstract Background Planning for return to work (RTW) is relevant among sub‐groups of metastatic breast cancer (mBC) survivors. RTW and protective factors in patients with mBC were determined. Methods Patients mBC, ages 18–63 years, identified Swedish registers, data collected starting 1 year before their diagnosis. The prevalence working net days (WNDs) (>90 >180) during the after diagnosis (y1) was Factors associated assessed using regression analysis. impact contemporary oncological...
In traditional Vietnamese culture the expectations on women were to get at least one son, who could carry lineage. 1980s, a two-child population policy was introduced and family planning campaigns intensified. The aim of this study explore women's experience in relation potentially conflicting demands their fertility. Data reproductive histories contraceptive use collected random sample survey among 206 age Thai Binh province, northern Vietnam. Qualitative data obtained interviews with...
Breast cancer constitutes 30% of all female cancers in Sweden. The median age for diagnosis is approximately 60 years. often hormone receptor-positive, i.e. the stimulated to grow by woman's own sex hormones.
We aimed to determine the longitudinal prevalence and predictors of sickness absence (SA) disability pension (DP) in breast cancer (BC) women who eventually developed relapse.A total 1293 BC women, were ages 20-63 years, diagnosed between 1996 2011 by 2016 had all relapse, identified Swedish registers followed from two years before five after their primary diagnosis, while they relapse-free. Annual SA DP was calculated. Logistic regression used estimate adjusted odds ratios (AOR) for...
Abstract GBM AGILE(NCT03970447) is a phase 2/3 Bayesian adaptive registration platform trial testing multiple therapies against common control. Paxalisib, PI3K/mTOR inhibitor, the 3rd arm in to conclude evaluation. METHODS Paxalisib was open patients with newly diagnosed unmethylated (NDU) and recurrent (RD) glioblastoma, three possible signatures: NDU, RD, All(NDU+RD). Arm enrollment occurred Dec2020 through May2022. Control were enrolled from study initiation (July2019) treated...
Women with newly diagnosed hormone receptor-positive breast cancer are offered adjuvant endocrine therapy (AET). Despite the survival benefits of therapy, a significant proportion patients do not adhere to anti-hormonal medication.
Abstract Disclosure: T. Lakshmikanth: None. C. Consiglio: F. Sardh: R. Forlin: J. Wang: Z. Tan: H. Barencilla: L. Rodriguez: Sugrue: P. Noori: M. Ivanchenko: Piñero Páez: Gonzalez: Habimana Mugabo: A. Johnsson: Ryberg: Å. Hallgren: Pou: Y. Chen: Mikeš: James: P.M. Dahlqvist: Wahlberg Hughes: Hagelin: Holmberg: Degerblad: Isaksson: D. Duffy: O. Kampe: N. Landegren: Brodin: Immune system adaptation during gender-affirming testosterone treatment Infectious, inflammatory and autoimmune...
Purpose:The aim of this study was to examine if breast cancer patients' estimated life satisfaction affected during adjuvant endocrine treatment, changed over time and there were any differences in between patients who experienced side effects from the treatment those did not. Material methods:Consecutive (n=68) referred for after radical surgery at an oncology clinic enrolled November 2002 August 2004.The scored their inclusion, about 2 years completing treatment.The questionnaire LiSat-11...
Objective The objective of this study is to determine the prevalence and predictors sickness absence (SA) disability pension (DP) in women with metastatic breast cancer (mBC). Methods Data were obtained from Swedish registers concerning 1,240 adult diagnosed 1997–2011 mBC, 1 year before (y−1) 2 (y1) (y2) years after diagnosis. SA DP was calculated. Odds ratios (AOR) determined for factors associated using long-term (SA > 180 days or 0 days) benefits. Results Prevalence 56.0% 24.8% during...
Breast cancer is the most common female worldwide.In majority of cases, breast tumour hormone receptor-positive and woman prescribed 5 years adjuvant anti-hormonal therapy.Many women experience side effects from treatment.Symptoms can be so severe that some choose to discontinue treatment.This study was conducted in order find methods support treated with therapy complete their treatment, by elucidating how they act reflect on coping rehabilitation-related issues.The includes twelve two...