- Islamic Finance and Communication
- Public Health and Nutrition
- COVID-19 Prevention and Impact
- SMEs Development and Digital Marketing
- Education and Communication Studies
- Signaling Pathways in Disease
- Employee Performance and Management
- Diet and metabolism studies
- Pregnancy and preeclampsia studies
- Healthcare Quality and Satisfaction
- Educational Methods and Impacts
- Cancer-related gene regulation
- Educational Methods and Media Use
- Methodologies in Health Research and Practice
- Maternal and fetal healthcare
- Immunotherapy and Immune Responses
- Legal Studies and Policies
- Marriage and Family Dynamics
- Education, Sociology, Communication Studies
- Public Administration in Developing Nations
- Vitamin D Research Studies
- Legal and Social Justice Studies
- NF-κB Signaling Pathways
- Islamic Studies and Radicalism
- Diet, Metabolism, and Disease
Sriwijaya University
2010-2025
Universitas Jayabaya
2024
Universitas Garut
2023
Comprehensive Cancer Center Mainfranken
2014-2023
Sebelas Maret University
2023
University of Würzburg
2014-2021
Universitas Borobudur
2021
Centre International de Recherche sur le Cancer
2015
Universitas PGRI Adi Buana Surabaya
2013-2015
Universitas PGRI Semarang
2013-2015
Circulating microRNAs (miRNAs) are emerging as useful non-invasive markers of disease. The objective this study was to use a mouse model prostate cancer tool discover serum miRNAs that could be assessed in clinical setting. Global miRNA profiling identified 46 at significantly altered levels (p ≤ 0.05) the TRansgenic Adenocarcinoma Mouse Prostate (TRAMP) mice with advanced compared healthy controls. A subset these known human homologues were validated an independent cohort and then measured...
Background and Objectives: The pathogenesis of placenta accreta spectrum disorder (PASD) is influenced by the inflammatory process. Therefore, examination biomarkers related to process, namely Matrix Metalloproteinase (MMP) CXC Motif Chemokine Receptor 2 (CXCR2) expected bring researchers a bright spot regarding PASD. This study analyzes role CXCR2, MMP-2, MMP-9 in PASD as well their potential correlation with 25-OHD, zinc, calcium ion levels. Methods: An observational case control design...
Introduction: In reconstructive surgery, free flaps are a superior method for resurfacing defects. While flap viability is typically monitored by subjective clinical examination, lactate and glucose levels in flaps, which can affect tissue metabolism during ischaemia reperfusion, help predict viability. This study aims to review previous research provide theoretical basis using artificial intelligence measurement as means of assessing viability.Method: The primary databases used retrieve the...
Background and Objectives: The pathogenesis of placenta accreta spectrum disorder (PASD) is influenced by the inflammatory process. Therefore, examination biomarkers related to process, namely matrix metalloproteinase (MMP) CXC motif chemokine receptor 2 (CXCR2), expected bring researchers a bright spot regarding PASD. This study analyzes role CXCR2, MMP-2, MMP-9 in Materials Methods: An observational with case–control design was conducted assess differences mean density immunostaining...
The massive infiltration of lymphocytes into the skin is a hallmark numerous human disorders. By co-culturing murine keratinocytes with splenic T cells we demonstrate here that affect and control synthesis secretion chemokines by keratinocytes. While pre-activated CD8+T induce CXCL9 CXCL10 in keep check CXCL1, CXCL5 CCL20, dampen CCL3 CCL4 cells. One key molecule IFN- synthesized under NFATc1 NFATc2. deficient for both NFAT factors are unable to expression. In addition, induced type I...
Abstract BACKGROUND Krüppel‐like factor ( KLF ) 6 is a candidate tumor suppressor gene in prostate cancer, but the mechanisms contributing to its loss of expression are poorly understood. We characterized KLF6 and DNA methylation status during tumorigenesis humans mice. METHODS was assessed matched human non‐malignant (NM) tissues (n = 22) by quantitative real‐time PCR (qPCR) three independent cancer cohorts bioinformatically. QPCR for methylation‐sensitive (MSP) were performed LNCaP cells...
In peripheral lymphocytes, the transcription factors (TFs) NF-κB, NFAT, and AP-1 are prime targets of signals that emerge from immune receptors. Upon activation, these TFs induce gene networks orchestrate growth, expansion, effector function lymphocytes. NFAT NF-κB share several properties, such as a similar mode induction architecture in their DNA-binding domain, there is subgroup κB-like DNA promoter motifs bound by both types TFs. However, unlike interact collaborate binding to DNA, seem...
Investigation into the mechanism underlying excessive trophoblast invasion yields further strategies and insights for diagnosis treatment of placenta accreta spectrum disorder (PASD). We conducted a comprehensive literature review to analyze relationship between CXCR2 expression PASD, as well possibility being used therapeutic diagnostic biomarker PASD. Chemokines are well-known mediators in immune system, particularly cell recruitment, angiogenesis, tumor infiltration. is an important...
The diagnosis of thyroid neoplasms necessitates the identification distinct histological features. Various education/hospital centers located in cities across Indonesia likely result discordances among pathologists when diagnosing neoplasms.
One of the crucial issues legal problems that is still a pro and con in society extraordinary effort judicial review by public prosecutor. The research to analyze implementation submission efforts prosecutor against criminal cases based on statutory regulations find formulation ideal case system realize justice certainty Indonesia. This uses type normative juridical research. Research philosophical approach, approach comparative approach. sources materials collected are analyzed...
The link between the extensive usage of calcineurin (CN) inhibitors cyclosporin A and tacrolimus (FK506) in transplantation medicine increasing rate opportunistic infections within this segment patients is alarming. Currently, how peritoneal are favored by these drugs, which impair activity several signaling pathways including Ca(++) /CN/NFAT, /CN/cofilin, /CN/BAD, NF-κB networks, unknown. Here, we show that Saccharomyces cerevisiae infection resident macrophages triggers transient nuclear...
Cognitive function includes learning, remembering and using acquired information. Emerging studies indicate the correlation between microbiota cognitive function. Higher abundance of a specific gut microbiota, such as Bacteroidetes may improve abilities. However, another study reported different result. These results suggest that further systematic analysis is required to determine effect on development. The aim this summarize development meta-analysis. PubMed, ScienceDirect, Clinical-Key...
Ketogenic diets (KD) have become popular diet to lose weight. However, the effect of such on brain function has not yet been clarified. Thus, we aimed study effects KD neurogenesis and apoptosis in dentate gyrus by assessing expression Ki-67 Caspase-3. Rats (n = 24) were divided into four groups: control (normal diet), ketogenic (KD), time-restricted (TRD), combination high-fat (CD) groups. The TRD CD groups was higher compared others (P < 0.05), whereas no difference observed group. number...
Exclusive breastfeeding for 6 months is a global strategies to promote the growth, development, health and survival of infants. Despite many benefits exclusive infants, mothers, families communities, coverage still low in countries including Indonesia. Mother's milk produced from collaboration between mechanical stimulation hormonal nerve factors. One hormones that affects estrogen. The hormone estrogen sex by uterus stimulate growth organs such as breasts pubic hair regulate menstrual...
Abstract Birthweight is the quality of maternal nutrition during pregnancy. In 2005, more than 20 million infants in world (15.5% all births) experienced low birth weight. Efforts to improve survival infants. Moringa oleifera leaf extract a medicinal plant that plays roles increase mother’s milk production. Determine effect extracts supplementation mamma alveolar diameter breastfeeding and weight infant Wistar rat. This was Completely Randomized Design, conducted October-March 2018. The...
Obesity is a problem of global epidemics and arise health threat to people. The prevalence obesity in the United States 2016 was around 39.8% adults aged 40-59 years 18.5% young 20-39 years. One dietary patterns used overcome ketogenic diet. main metabolic reaction due diet occurs liver which make lesion. The high-fat diet, quite protein, low carbohydrates (usually less than 50 g / day). effect on is help maintain TCA cycle homeostasis, prevents accumulation intermediate fatty acids that...
Neutrophil extracellular traps (NETs) are immune components found in a variety of pathological states. It has been shown to have either beneficial or harmful implications, depending on how it is controlled and particularly observed three major scenarios: infection, autoimmune disease, cancer. In this article, we compiled some the roles NETs conditions, as well benefits targeting them for improved patient outcomes. The role were primarily positive infectious whether caused by bacteria, virus,...