Monica Focşan

ORCID: 0000-0001-6735-5146
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About
Contact & Profiles
Research Areas
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Advanced biosensing and bioanalysis techniques
  • Biosensors and Analytical Detection
  • Nanoplatforms for cancer theranostics
  • Nanocluster Synthesis and Applications
  • Nanoparticle-Based Drug Delivery
  • Advanced Nanomaterials in Catalysis
  • Plasmonic and Surface Plasmon Research
  • Advanced Photocatalysis Techniques
  • Graphene and Nanomaterials Applications
  • Photodynamic Therapy Research Studies
  • Advanced Biosensing Techniques and Applications
  • Nanoparticles: synthesis and applications
  • Luminescence and Fluorescent Materials
  • Carbon and Quantum Dots Applications
  • Photoacoustic and Ultrasonic Imaging
  • Quantum Dots Synthesis And Properties
  • Protein Interaction Studies and Fluorescence Analysis
  • Retinal Diseases and Treatments
  • Porphyrin and Phthalocyanine Chemistry
  • Phenothiazines and Benzothiazines Synthesis and Activities
  • Synthesis and Characterization of Heterocyclic Compounds
  • Gas Sensing Nanomaterials and Sensors
  • Photochromic and Fluorescence Chemistry
  • Electrocatalysts for Energy Conversion

Babeș-Bolyai University
2016-2025

Spitalul Clinic Județean de Urgență Cluj-Napoca
2015-2016

École Normale Supérieure de Lyon
2014

Université Claude Bernard Lyon 1
2014

Centre National de la Recherche Scientifique
2014

Laboratoire Interdisciplinaire de Physique
2011

The integration of metal-enhanced fluorescence (MEF) and surface-enhanced Raman scattering (SERS) onto single plasmonic nanoparticles is highly desirable to boost up accuracy sensitivity in spectroscopic investigations. In this work, we demonstrate the feasibility performing both MEF SERS analysis on gold nanorods (GNRs) decorated with a unique molecular probe, here Rose Bengal (RB) fluorophore. While cetyltrimethylammonium bromide layer GNRs captures RB molecules preventing quenching,...

10.1021/jp211954m article EN The Journal of Physical Chemistry C 2012-05-15

In this work, we developed a new pH- and temperature-responsive nanochemotherapeutic system based on Doxorubicin (DOX) noncovalently bound to biosynthesized gelatin-coated gold nanoparticles (DOX-AuNPs@gelatin). The real-time release profile of DOX was evaluated at different pH values (7.4, 5.3, 4.6) temperatures (22-45 °C) in aqueous solutions, its therapeutic performance examined vitro against MCF-7 breast cancer cells. TEM, dark-field scattering, wide-field fluorescence microscopy...

10.1021/acsami.6b07583 article EN ACS Applied Materials & Interfaces 2016-08-18

Abstract The Coronavirus disease 2019 (COVID‐19) emergency has demonstrated that the utilization of face masks plays a critical role in limiting outbreak. Healthcare professionals utilize all day long without replacing them very frequently, thus representing source cross‐infection for patients and themselves. Nanotechnology is powerful tool with capability to produce nanomaterials unique physicochemical antipathogen properties. Here, how realize non‐disposable highly comfortable respirators...

10.1002/chem.202004875 article EN Chemistry - A European Journal 2020-12-07

Sea buckthorn oil, derived from the fruits of shrub, also termed seaberry or sandthorn, is without doubt a strikingly rich source carotenoids, in particular zeaxanthin and β-carotene. In present study, sea oil an oil-in-water emulsion were subjected to simulated gastro-intestinal vitro digestion, with main focus on xanthophyll bioaccessibility. Zeaxanthin mono- di-esters predominant carotenoids dipalmitate as major compound (38.0%). A typical fatty acid profile was found, palmitic (49.4%),...

10.3390/nu12010076 article EN Nutrients 2019-12-27

Fungal infections are a significant global health problem, particularly affecting individuals with weakened immune systems. Moreover, as uncontrolled antibiotic and immunosuppressant use increases continuously, fungal have seen dramatic increase, some strains developing resistance. Traditional approaches to identifying often rely on morphological characteristics, thus owning limitations, such struggles in several or distinguishing between similar morphologies. This review explores the...

10.1016/j.bios.2024.116243 article EN cc-by Biosensors and Bioelectronics 2024-03-24

Many microorganisms have long been known to be able synthesize nanoparticles either in extracellular media or inside cells but the biochemical mechanisms involved biomineralization are still poorly understood. In this paper we report intracellular synthesis of gold (GNPs) by cyanobacterium Synechocystis sp. PCC 6803 exposed an aqueous solution chloroauric acid. We assess interplay between process and metabolic activities (i.e. photosynthesis respiration) cyanobacteria correlating GNP yield...

10.1088/0957-4484/22/48/485101 article EN Nanotechnology 2011-11-09

Abstract Early medical diagnostic in nanomedicine requires the implementation of innovative nanosensors with highly sensitive, selective, and reliable biomarker detection abilities. In this paper, a dual Localized Surface Plasmon Resonance - Enhanced Raman Scattering (LSPR- SERS) immunosensor based on flexible three-dimensional (3D) gold (Au) nanocups platform has been implemented for first time to operate as relevant “proof-of-concept” specific antigen-antibody binding events, using human...

10.1038/s41598-017-14694-1 article EN cc-by Scientific Reports 2017-10-23

In this work, we demonstrate the feasibility of gold bipyramidal-shaped nanoparticles (AuBPs) to be used as active plasmonic nanoplatforms for detection biotin–streptavidin interaction in aqueous solution via both Localized Surface Plasmon Resonance and Enhanced Raman Scattering (LSPR/SERS). Our proof concept exploits precise attachment recognition element at tips AuBPs, where electromagnetic field is stronger, which beneficial surface sensitivity longitudinal LSPR on local refractive index...

10.1021/acs.analchem.8b01689 article EN Analytical Chemistry 2018-06-15

This study presents two new hybrid nanosystems (G-PMA(1:1)@AuBPs, G-PMA(1:3)@AuBPs), constructed from amine graphene (G-NH2) functionalized with poly(methacrylic acid) (PMA) and gold nanoparticles a bipyramidal shape (AuBPs). The nanoplatforms behave...

10.1039/d5tb00097a article EN cc-by Journal of Materials Chemistry B 2025-01-01

Abstract In this work, we investigate the optical properties of large-scale, ordered silver-coated polystyrene microspheres films fabricated on glass substrate using convective self-assembly (CSA) method, with goal their application as active plasmonic for Surface-Enhanced Raman Spectroscopy (SERS). We film an optimized CSA protocol a custom-built equipment. Scanning electron microscopy (SEM) reveals close-packed large area monolayer intact microspheres. The were characterized experimentally...

10.1088/1402-4896/adbd80 article EN Physica Scripta 2025-03-06

Numerous research efforts are investigating the possibility of using light interactions with metallic nanoparticles to improve fluorescence properties nearby molecules. Few investigations have considered encapsulation molecules in nanocavities. In this paper, we present optical new hybrid consisting gold nanoshells and fluorescent organic dyes their liquid cores. Microspectroscopy on single nanoparticle demonstrates that extinction spectra good agreement Mie's theory. Finite difference time...

10.1021/nl2004847 article EN Nano Letters 2011-04-08
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