- Analytical Chemistry and Sensors
- Nanowire Synthesis and Applications
- Neuroscience and Neural Engineering
- Advanced biosensing and bioanalysis techniques
- Conducting polymers and applications
- Microfluidic and Bio-sensing Technologies
- Molecular Junctions and Nanostructures
- Advancements in Semiconductor Devices and Circuit Design
- Electrochemical sensors and biosensors
- Thermal properties of materials
- Advanced Sensor and Energy Harvesting Materials
- Electrochemical Analysis and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Advanced Memory and Neural Computing
- Semiconductor materials and devices
- Thermography and Photoacoustic Techniques
- Graphene research and applications
- Force Microscopy Techniques and Applications
- Plasmonic and Surface Plasmon Research
- Photonic and Optical Devices
- Graphene and Nanomaterials Applications
- Optical Coatings and Gratings
- Physical Unclonable Functions (PUFs) and Hardware Security
- Biosensors and Analytical Detection
- Injection Molding Process and Properties
RWTH Aachen University
2015-2024
University of Applied Sciences Kaiserslautern
2011-2021
Ramboll (Germany)
2016-2017
Forschungszentrum Jülich
2008-2010
Jülich Aachen Research Alliance
2009-2010
Objective. Electric stimulation delivered by implantable electrodes is a key component of neural engineering. While factors affecting long-term stability, safety, and biocompatibility are topic continuous investigation, widely-accepted principle that charge injection should be reversible, with no net electrochemical products forming. We want to evaluate oxygen reduction reactions (ORR) occurring at different electrode materials when using established protocols.Approach. As electrodes, we...
As a source of clean energy, hydrogen (H2) is promising alternative to fossil fuels in reducing the carbon footprint. However, due highly explosive nature H2, developing high-performance sensor for real-time detection H2 gas at low concentration essential. Here, we demonstrated sensing performance Ag/Pd nanoparticle-functionalized ZnO nanoplates. Bimetallic nanoparticles with an average size 8 nm were prepared and decorated on surface nanoplates enhance performance. Compared pristine ZnO,...
Abstract Surface plasmon resonance (SPR) is a key technique in developing sensor platforms for clinical diagnostics, drug discovery, food quality, and environmental monitoring applications. While prism‐coupled (Kretschmann) SPR remains “gold‐standard” laboratory work‐flows due to easier fabrication, handling high through put, other configurations such as grating‐coupled (GC‐SPR) wave‐guide mode are yet fulfil their technology potential. This work evaluates the technical aspects influencing...
Silicon nanowire (NW) transistors were fabricated in a top-down process. These devices used to record the extracellular potential of spontaneous activity cardiac muscle HL-1 cells. Their signals measured by direct dc sampling drain current. An improved signal-to-noise ratio compared planar field-effect was observed. Furthermore signal shape evaluated and could be associated different membrane currents. With these experiments, qualitative description properties cell-NW contact obtained...
Abstract We describe the fabrication, electrical and electrochemical characterization of silicon nanowire arrays, which were processed in a top‐down approach using combined nanoimprint lithography wet chemical etching. used top layer as contact line observed an influence implantation subsequent annealing these lines to device performance. In addition we found subthreshold slope dependence on wire size. When operated liquid environment, wires can be utilized pH sensors. characterized...
We introduce a novel technique of impedimetric sensing cellular adhesion, which might have the potential to supplement well-known Electrical Cell-substrate Impedance Sensing (ECIS) in cell culture assays. In contrast already commercialized ECIS method, we are using ion-sensitive field-effect transistor (ISFET) devices. The standard gold microelectrode size is range 100-250 μm diameter. Reason for this limitation that when downscaling electrodes, their effective impedance governed by...
As a prerequisite to the development of real label-free bioassay applications, high-throughput top-down nanofabrication process is carried out with combination nanoimprint lithography, anisotropic wet-etching, and photolithography methods realizing nanoISFET arrays that are then analyzed for identical sensor characteristics. Here, newly designed array-based chip exhibits 32 high aspect ratio silicon nanowires (SiNWs) laid in parallel 8 unit groups connected very highly doped, Π-shaped common...
Highly sensitive electrical detection of biomarkers for the early stage screening cancer is desired future, ultrafast diagnostic platforms. In case prostate (PCa), prostate-specific antigen (PSA) prime interest and its in combination with other PCa-relevant a multiplex approach advised. Toward this goal, we demonstrate label-free, potentiometric PSA silicon nanowire ion-sensitive field-effect transistor (Si NW-ISFET) arrays. To realize detection, utilized DNA aptamer-receptors specific PSA,...
ou non, émanant des établissements d'enseignement et de recherche français étrangers, laboratoires publics privés.
Abstract We report the fabrication of a silicon nanowire (SiNW) transistor array realized in top‐down process on 4′′ silicon‐on‐insulator (SOI) wafers. This is second, optimized version combining thermal nanoimprint lithography and wet chemical etching to define planar nanowires contact lines out top layer one step. used ion implantation reduce series resistance source drain lines. In total 56 individually addressable SiNWs were aligned two Wires dimensions down 60 nm width 40 height having...
Abstract Rapid and frequent screening of cytokines as immunomodulation agents is necessary for precise interventions in severe pathophysiological conditions. In addition to high-sensitivity detection such analytes complex biological fluids blood, saliva, cell culture medium samples, it also crucial work out miniaturized bioanalytical platforms with potential high-density integration enabling multiple analytes. this work, we show a compact, point-of-care-ready platform interleukin-4 (IL-4)...
It is highly desirable to enhance the heat conduction of polymeric heat-dissipating materials for applications in power electronics, automotive components, light-emitting diodes, and telecommunication equipment. However, thermal conductivity one three orders magnitude lower than that metals ceramics due phonon scattering amorphous regions. Several attempts have been made overcome this limitation by increasing flow along orientation axis self-assembly liquid crystalline polymers, but design...
In this work, we present a reduced graphene oxide‐based impedimetric histamine biosensor. Histamine as bioamine mediates immune‐modulatory effects in acute inflammatory and allergic reactions. proof‐of‐principle approach, the low‐cost sensor platform determines low concentrations of buffer solution with an readout technique. As used ultra‐thin oxide lines fabricated by simple soft‐lithographic approach. The about 20 μm width were characterised atomic force microscopy scanning electron...
Silicon nanowires (SiNW) are highly sensitive to biomolecules. In some publications, changes of SiNW conductance in relation their concentration levels displayed. Upon binding, biomolecule charges change the surface potential and, thereby, conductance. We discussed earlier that SiNWs can be regarded as long‐channel, ion‐sensitive field‐effect transistors (ISFETs). The choice a stable working point is important and defines common detection principle based on shift threshold voltage....
We present silicon nanowire (SiNW) devices, which were fabricated in a top-down process from silicon-on-insulator (SOI) substrates with high yield. Electronic characterization proved reliable electronic properties. Here we report the versatile use of devices different applications like label-free sensing DNA hybridization, detection cellular signals, and proteins. Compared to micro-sized SiNWs show an improved sensitivity. Analyses cell-nanowire contact showed that important seal resistance...