A5072283825- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Cervical and Thoracic Myelopathy
- Social Media in Health Education
- Mobile Health and mHealth Applications
- Digital Mental Health Interventions
- Periodontal Regeneration and Treatments
- Microscopic Colitis
- Inflammatory Bowel Disease
- Bone Tissue Engineering Materials
- Total Knee Arthroplasty Outcomes
- Phytochemistry and biological activity of medicinal plants
- Plant chemical constituents analysis
- Knee injuries and reconstruction techniques
- Bioactive natural compounds
- Pharmacological Effects of Natural Compounds
- Phagocytosis and Immune Regulation
- Innovations in Medical Education
- Musculoskeletal pain and rehabilitation
- Telemedicine and Telehealth Implementation
- Hip disorders and treatments
- Vitamin C and Antioxidants Research
- Gastroesophageal reflux and treatments
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Genetic and Kidney Cyst Diseases
Peking University Third Hospital
2017-2025
Peking University
2017-2025
Macau University of Science and Technology
2025
Shandong Provincial QianFoShan Hospital
2018-2024
Shandong First Medical University
2023-2024
China Academy of Information and Communications Technology
2019
Shandong University
2014-2018
Sichuan University
2016-2017
West China Hospital of Sichuan University
2016-2017
Fuzhou University
2016
Summary The development of thrombosis in polycythaemia vera (PV) involves multifactorial processes including pathological activation blood cells. Release microparticles (MPs) by activated cells diseases is associated with thrombotic risk, but relatively few data are available PV. aim the present study was to investigate increase MP release and exposure phosphatidylserine (PS) on outer membrane MP-origin patients PV, analyse their procoagulant activity (PCA). PS-positive MPs were detected...
Objectives: This bibliometric analysis investigates recent research trends in biologics and small molecules for treating inflammatory bowel disease (IBD) based on literature from the past decade. Methods: cross-sectional study involved analyzing data retrieved Web of Science Core Collection (WoSCC) database to examine evolution thematic biological agents small-molecular drugs IBD conducted between 1 January 2014, 20 September 2024. VOSviewer software was utilized assess co-authorship,...
Objective: For patients with chronic diseases requiring long-term use of medications who are quarantined at home, the management medication therapy during COVID-19 pandemic is a problem that pharmacists urgently need to discuss and solve. The study aims establish launch telepharmacy framework implement pharmaceutical care pandemic. Methods: To remote pharmacy service model based on consultation platform under official account "Beijing Pharmacists Association" social software WeChat app,...
Administration of various chemotherapeutic agents is associated with an increased risk thrombotic events. Although vascular endothelium plays a predominant role in blood coagulation and fibrinolysis, the effect cytotoxic drugs on procoagulant activity (PCA) endothelial cells has not been well evaluated. Our study aims to investigate possibility that daunorubicin, agent, exerts prothrombotic cells. We tested impact daunorubicin phosphatidylserine (PS) exposure, microparticles (EMPs) release...
Articular cartilage defects are a major clinical burden worldwide. Current methods to repair bone include autografts, allografts and external fixation. In recent years, the of by tissue engineering has emerged as promising approach. The present study aimed assess novel method using biological reactor with platelet‑rich plasma construct tissue‑engineered bone. Beagle marrow mesenchymal stem cells (BMSCs) were isolated differentiated into osteoblasts chondroblasts tricalcium phosphate...
Previous studies reported that the location of center rotation (COR) at instrumented level after cervical total disc replacement (TDR) deviated from its preoperative location. However, currently, it is unknown whether COR linked to range motion (ROM) level. The purpose this study was evaluate clinical outcomes TDR with ProDisc-C (Synthes, West Chester, PA, USA), as well investigate change and significance.A 23 patients who underwent single-level were included. Japanese Orthopaedic...
A retrospective cohort study. Plated cervical laminoplasty is an increasingly common technique. unique facet joint disturbance induced by lateral mass miniscrews penetrating articular surface was noticed. Facet joints are important to maintain spine stability and kinetic balance. Whether this could affect clinical radiologic results still unknown. The objective of study investigate the outcomes patients with in plated laminoplasty. total 105 who underwent miniplate fixation between May 2010...
The aim of the present study was to establish a novel animal model osteonecrosis femoral head (ONFH) using magnetic resonance imaging (MRI)‑guided argon‑helium cryotherapy system. A total 48 rabbits were used generate ONFH models. In group I, left received two cycles freezing‑thawing under MRI guidance, while in II, right each rabbit only one cycle freezing‑thawing. X‑ray and histological examinations performed. percentages lacunae heads I at weeks 4, 8 12 following surgery (49.75±3.17,...
The aim of the present study was to construct tissue-engineered bone using a bioreactor and platelet-rich plasma (PRP). Bone marrow mesenchymal stem cells (BMSCs) β-tricalcium phosphate (β-TCP) were cultured in perfusion with PRP-containing medium for 21 days form BMSC-TCP composite. Rabbits then implanted morphology composite observed three months after surgery by scanning electron microscopy hematoxylin eosin (H&E) staining. In addition, expression cluster differentiation (CD)31 von...
A study was designed to quantify the extent of porous osseointegration at prosthesis-bone interface in Prestige LP prosthesis containing a plasma-sprayed titanium coating. Using an anterior surgical approach, cervical disc arthroplasty performed 8 mature male goats C3-C4 segment, followed by implantation prosthesis. The vertebral specimens were examined using microcomputed tomograph for histomorphometric quantification, and proceeded routine paraffin processing histological observation....
In cervical artificial disc replacement (C-ADR), sometimes we encountered with such cases that implants of adjacent height both fit the target space properly. No study was available discussing choice implant and clinical outcomes under circumstance. The purpose this to evaluate impact different heights on radiographic results when This retrospective included 34 patients underwent single-level C-ADR at C5–C6 level our institution. these patients, either 5 mm or 6 surgical properly without...
Introduction: Atlantoaxial instability is a common and serious injury of the upper cervical spine. Brooks’ procedure widely used to reconstruct unstable atlantoaxial joint. The migration into spinal cord titanium cable spontaneous fusion between C2 C3 has been little reported management such patient difficult. We describe an unusual case fatigue failure posterior fixation with C3. Case report: A 16-year-old girl complained cervico-occipital pain numbness weakness extremities 3 months ago....
Kurarinone is a major component found in the dried roots of Sophora flavescens Ait. that participates vital pharmacological activities. Recombinant CYP450 supersomes and liver microsomes were used to study metabolic profiles kurarinone its inhibitory actions against cytochrome P450 (CYP) UDP‐glucuronosyltransferase (UGT) enzymes. 100 μ M strongly inhibited more than 90% UGT1A1, UGT1A6, CYP1A2, CYP2C9. CYP1A2 CYP2D6 played important roles catalyzing biotransformation kurarinone. Moreover,...