A5025964447- Plant Pathogenic Bacteria Studies
- Plant-Microbe Interactions and Immunity
- Plant Pathogens and Fungal Diseases
- RNA and protein synthesis mechanisms
- Chromosomal and Genetic Variations
- Genomics and Phylogenetic Studies
- Plant Disease Resistance and Genetics
- Fungal Infections and Studies
- Aquatic Invertebrate Ecology and Behavior
- Study of Mite Species
- Plant Virus Research Studies
- Legume Nitrogen Fixing Symbiosis
- Glycosylation and Glycoproteins Research
- Fish Ecology and Management Studies
- Parasite Biology and Host Interactions
- Evolution and Genetic Dynamics
- CRISPR and Genetic Engineering
- Freshwater macroinvertebrate diversity and ecology
- RNA modifications and cancer
- Biochemical and Structural Characterization
- Amphibian and Reptile Biology
- Ecology and Vegetation Dynamics Studies
- Antifungal resistance and susceptibility
- Plant and Fungal Interactions Research
- Yeasts and Rust Fungi Studies
Bristol Clinical Commissioning Group
2022
University of Otago
2007-2021
Rhizopus oryzae is the primary cause of mucormycosis, an emerging, life-threatening infection characterized by rapid angioinvasive growth with overall mortality rate that exceeds 50%. As a representative paraphyletic basal group fungal kingdom called "zygomycetes," R. also used as model to study evolution. Here we report genome sequence strain 99-880, isolated from fatal case mucormycosis. The highly repetitive 45.3 Mb assembly contains abundant transposable elements (TEs), comprising...
A recently emerged plant disease, bacterial canker of kiwifruit (Actinidia deliciosa and A. chinensis), is caused by Pseudomonas syringae pv. actinidiae (PSA). The disease was first reported in China Japan the 1980s. severe outbreak PSA began Italy 2008 has spread to other European countries. found both New Zealand Chile 2010. To study evolution pathogen analyse transmission between countries, genomes strains from (where genus Actinidia endemic), Italy, were sequenced. are very similar....
ADHD in adults is a common and debilitating neurodevelopmental mental health condition. Yet, diagnosis, clinical management monitoring are frequently constrained by scarce resources, low capacity specialist services limited awareness or training both primary secondary care. As result, many people with experience serious barriers accessing the care they need.Professionals across primary, secondary, tertiary met to discuss adult United Kingdom. Discussions identified constraints service...
Archey's frog Leiopelma archeyi is a critically endangered New Zealand endemic species. The discovery of the emerging infectious disease, chytridiomycosis, in wild populations this raised concern that disease may drive species to extinction. Twelve wild-caught frogs naturally infected with amphibian chytrid fungus Batrachochytrium dendrobatidis were monitored captivity by observing clinical signs, measuring weight gain, and performing repeated PCR tests. Eight treated topical...
A new group of transposable elements, which the authors have named cryptons, was detected in several pathogenic fungi, including basidiomycete Cryptococcus neoformans , and ascomycetes Coccidioides posadasii Histoplasma capsulatum . These elements are unlike any previously described transposons. An archetypal member group, crypton Cn1 is 4 kb length present at a low but variable copy number variety C. strains. It displays interstrain variations its insertion sites, suggesting recent...
The bacterial canker of kiwifruit by Pseudomonas syringae pv. actinidiae is an emblematic example a catastrophic disease fruit crops. In 2008 new, extremely virulent form the pathogen emerged and rapidly devastated many Actinidia spp. orchards all over world. order to understand differences in populations within this pathovar elucidate their diffusion movements on world scale, it necessary be able quickly routine basis compare new isolates with previous records. report worldwide collection...
The modern pandemic of the bacterial kiwifruit pathogen Pseudomonas syringae pv actinidiae (Psa) is caused by a particular Psa lineage. To better understand genetic basis virulence this lineage, we compare completely assembled genome New Zealand strain with that type first isolated in Japan 1983. Aligning two genomes shows numerous translocations, constrained so as to retain appropriate orientation Architecture Imparting Sequences (AIMs). There are several large horizontally acquired...
Abstract Background We recently described a mini-intein in the PRP8 gene of strain basidiomycete Cryptococcus neoformans , an important fungal pathogen humans. This was second intein nuclear genome any eukaryote; first encoded found VMA several saccharomycete yeasts. The evolution eukaryote inteins is not well understood. In this report we describe additional (bringing total these to over 20). compare and contrast phylogenetic distribution evolutionary history intein, order derive broader...
Abstract We have used comparative sequence analysis to identify an intein‐like (protein splicing element) present in Cryptococcus neoformans , a fungal pathogen of humans. The encoding this element is the C. PRP8 gene, as in‐frame insertion relative genes other organisms. It contains sequences similar those protein‐splicing domains two previously described yeast inteins (in Saccharomyces cerevisiae and Candida tropicalis ), although it lacks any recognizable internal endonuclease domain....
Retrotransposons are mobile genetic elements. They can transpose via the reverse transcription of mRNA into double-stranded DNA (dsDNA) followed by insertion this dsDNA new sites within host genome. The unintegrated, linear, form retrotransposons is usually very rare. We report here isolation a retrotransposon from Candida albicans which unusual in respect. This element, we have named pCal, was first identified as distinct band when uncut C. examined on an agarose gel. Sequence analysis...
Tca2 is a Ty1/copia-type retrotransposon from the pathogenic yeast Candidaalbicans. It was originally identified as an abundant, linear, extrachromosomal, double-stranded DNA molecule. Here we show that widespread in C.albicans, but abundance of extrachromosomal varies greatly among different strains and strongly dependent on growth temperature. The relative levels RNA vary similar pattern to DNA, raising possibility variations are introduced predominantly at level transcription. We have...
Inteins are self-splicing protein elements. They translated as inserts within host proteins that excise themselves and ligate the flanking portions of (exteins) with a peptide bond. encoded in-frame insertions genes for proteins. found in all three domains life viruses, but have very sporadic distribution. Only small number intein coding sequences been identified eukaryotic nuclear genes, these from ascomycete or basidiomycete fungi.We seven second largest subunits RNA polymerase. These were...
We present the first complete genome sequence of a copper-resistant biovar 5 strain bacterial pathogen kiwifruit, Pseudomonas syringae pv. actinidiae. Comparison with copper-sensitive isolate indicates that copper resistance is encoded on plasmid.
We present here the complete genome sequence of M228, a Chinese biovar 3 strain Pseudomonas syringae pv. actinidiae, bacterial pathogen kiwifruit.
Abstract The invertebrates and macroalgae in 42 permanent temporary ponds kettles glacial moraine south of Lake Ohau, 36 sites west Tekapo, South Island, New Zealand, were sampled December 1980, taxonomic lists compiled. Most organisms belonged to taxa characteristically found shallow waters elsewhere but new distributions for the rare cladocerans Neothrix armata, Monospilus dispar, Ephemeroporus barroisi recorded, presence Simocephalus acutirostratus Zealand was confirmed. Darkly pigmented...
A water mite, Piona exigua, is the dominant invertebrate predator in some New Zealand lakes. To establish extent to which this has an impact on populations of its prey species, we have analysed effect availability quantitative estimates predation. We describe functional responses generated under a range conditions and compare them using «parallel curve analysis» maximum likelihood method estimating parameters