A5055047888- Cervical Cancer and HPV Research
- Atmospheric chemistry and aerosols
- Air Quality and Health Impacts
- Air Quality Monitoring and Forecasting
- Hepatitis B Virus Studies
- Molecular Biology Techniques and Applications
- Global Cancer Incidence and Screening
- Lung Cancer Diagnosis and Treatment
- Atmospheric Ozone and Climate
- Radiomics and Machine Learning in Medical Imaging
- Genital Health and Disease
- Reproductive tract infections research
- Nanoparticle-Based Drug Delivery
- Gastric Cancer Management and Outcomes
- COVID-19 Clinical Research Studies
- Endometrial and Cervical Cancer Treatments
- Medical Imaging Techniques and Applications
- Atmospheric and Environmental Gas Dynamics
- Atmospheric aerosols and clouds
- Asthma and respiratory diseases
- Ocean Acidification Effects and Responses
- Telomeres, Telomerase, and Senescence
- COVID-19 diagnosis using AI
- BRCA gene mutations in cancer
- Seaweed-derived Bioactive Compounds
Jiangsu University
2024-2025
Nanjing University of Chinese Medicine
2025
Jiangsu Province Hospital
2025
Guangzhou Experimental Station
2025
University of Electronic Science and Technology of China
2019-2024
Sichuan Cancer Hospital
2019-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2023
China Meteorological Administration
2023
National Yang Ming Chiao Tung University
2022
National Pingtung University of Science and Technology
2022
Generalized Additive Models (GAMs) are widely employed in ecological research, serving as a powerful tool for ecologists to explore complex nonlinear relationships between response variable and predictors. Nevertheless, evaluating the relative importance of collinear predictors on variables GAMs remains challenge. To address this challenge, we developed an R package named gam.hp. gam.hp calculates individual R2 values predictors, based concept 'average shared variance', method previously...
Abstract. Ozone (O3) pollution research and management in China have mainly focused on anthropogenic emissions, while the importance of natural processes is often overlooked. With increasing frequency extreme weather events, role exacerbating O3 gaining attention. In September 2022, Pearl River Delta (PRD) southern experienced an extended period (25 d) regional exceedances high temperatures (second highest over last 2 decades) due to conditions influenced by subtropical typhoon peripheries....
In recent years, the escalating ozone concentrations in urban areas of China have raised significant public concern. Due to lack long-term vertical observation, characteristics distribution and long-range transport are still not well understood. This study utilized 27 years (1994–2020) sounding observations Hong Kong, conjunction with ERA5 reanalysis data HYSPLIT backward model, examine structure three-dimensional cross-regional tropospheric over Kong. During spring, above 850 hPa found be...
Abstract Background The causal role of high-risk Human papillomavirus (HR-HPV) in the pathogenesis anogenital cancers is well established. In contrast, information on HR-HPV distribution continuous anatomic sites within female genital tract limited, and impact sample type clinical performance HPV-based cervical cancer screening warrants investigation. Methods A total 2,646 Chinese women were enrolled study from May 2006 to April 2007. We analyzed infection features by status pathological...
Although human papillomavirus (HPV) infection plays a decisive role in causing tumors, its is insufficient for independently promoting cancer development and other co-factors facilitate the carcinogenic process. The objective of this study was to demonstrate association between vaginal microbiota high-risk (HR-HPV) women with without bacterial vaginosis (BV). included 1015 aged 21-64 who participated cervical screening two areas China from 2018 2019. Women were collected exfoliated cell...
Based on the observation and reanalysis data in Guangdong from 2015 to 2020, variation characteristics of ozone （O3） concentration four typical cities were analyzed, effects meteorological factors O3 different seasons revealed based generalized additive model （GAM）. The daily maximum 8-hour average （O3_8h） increased significantly 2019, with a trend 5.0 μg·m-3·a-1, decreased slightly 2020 Guangdong. O3_8h total number polluted days substantially higher autumn than those other showed cities....
Phloretin exhibits strong antioxidant and anti-aging properties by inhibiting mitochondrial oxidation of glutamate, succinic acid, ascorbic acid. However, its clinical application is limited poor aqueous solubility low oral bioavailability. To enhance bioavailability efficacy, we incorporated phloretin into nano-micelles (phloretin-MM) using the thin film dispersion method. Characterization revealed that optimal formulation had TPGS Pluronic F68 in a 4:1 ratio as excipients, which resulted...
The clinical application of Isoquercitrin (IQ) is limited by its low water solubility and short retention time in the body, despite diverse pharmacological effects. To address these issues, we prepared polyethylene glycol (PEG)-modified IQ liposomes (IQ-L) using thin film dispersion method optimized formulation through a combination One Factor at Time (OFAT) response surface experiments. Characterization IQ-L that was optimal revealed particle size 185.48 nm, polydispersity index 0.252, zeta...
Rapid urbanization and associated transportation play a crucial role in the distribution of heavy metals road dust, leading to serious environmental health concerns. This study explored concentration spatial variability metals, including cadmium (Cd), copper (Cu), lead (Pb), zinc (Zn), dust across six urban zones Guangdong Province (parks, educational, residential, commercial, traffic, industrial areas). The also evaluated bioavailability these determine their carcinogenic non-carcinogenic...
There are no large samples or exact prediction models for assessing the cancer risk factors of solitary pulmonary nodules (SPNs) in Chinese population. We retrospectively analyzed clinical and imaging data patients with SPNs who underwent computer tomography guided needle biopsy our hospital from Jan 1st 2011 to March 30th 2016. These were divided into a development set validation set. groups included 1078 344 patients, respectively. A model was developed validated using logistic regression....
Abstract Low‐cost, accurate high‐risk human papillomavirus (HR‐HPV) tests are needed for cervical cancer screening in limited‐resource settings. More than 200 cytological specimens from hospital patients were collected and analyzed a real‐world study. We evaluated the analytical clinical performance of four widely used HR‐HPV test (Tellgen, Hybribio, Liferiver, Sansure) based on real‐time polymerase chain reaction technology platforms, compared with cobas test. Cervical intraepithelial...
Abstract Women with positive high-risk human papillomavirus (hrHPV) need efficient triage testing to determine colposcopy referrals. Triage strategies of combining p16/Ki-67 extended HPV genotyping were evaluated in this study. In total, 899 women attending cervical cancer screening program and 858 referred from five hospitals recruited. All the participants tested by assays dual staining. Colposcopy biopsy performed on any abnormal results. genotypes divided into four strata (HPV16/18,...
Background: To investigate the human papillomavirus (HPV) genotype distribution among general population and assess attribution of HPV genotypes targeted by vaccines to protect against cervical lesions theoretically. Methods: Cervical samples were collected from women aged 21 64 years old Inner Mongolia Shanxi Province in China who had not been vaccinated HPV. type-specific absolute risk (AR) classified was calculated then attributable fraction (AF) estimated, together with combined...
Background: This study aimed to explore the current knowledge level of breast cancer among rural women in Southwest China and analyze influencing factors cognition.Methods: From May November 2022, 1468 were invited participate this study.Demographic information Chinese version Breast Cancer Awareness Measure (C-BCAM) collected through one-on-one investigations.The data analyzed using descriptive statistics, chi-square tests, multiple regression analysis SPSS 26.0. Results:The included a...