A5057477347- Epilepsy research and treatment
- Inflammatory Bowel Disease
- Microscopic Colitis
- Pharmacological Effects and Toxicity Studies
- Biosimilars and Bioanalytical Methods
- Neuroscience and Neuropharmacology Research
- Pharmaceutical studies and practices
- Autoimmune Neurological Disorders and Treatments
- Colorectal Cancer Screening and Detection
- Topic Modeling
- Healthcare professionals’ stress and burnout
- Inflammatory Myopathies and Dermatomyositis
- Hereditary Neurological Disorders
- Celiac Disease Research and Management
- Pediatric Hepatobiliary Diseases and Treatments
- Autoimmune and Inflammatory Disorders
- Transcranial Magnetic Stimulation Studies
- Adolescent and Pediatric Healthcare
- Genomics and Rare Diseases
- Peripheral Nerve Disorders
- Machine Learning in Healthcare
- Mitochondrial Function and Pathology
- Foreign Body Medical Cases
- Neurobiology of Language and Bilingualism
- Bacterial Infections and Vaccines
Flinders Medical Centre
1991-2024
Flinders University
2009-2024
Rush University Medical Center
2024
University of Vermont Medical Center
2019-2022
University of Vermont
2018
Oklahoma State University Oklahoma City
2005
Queen Elizabeth Hospital
2001
New York University Langone Orthopedic Hospital
1995
Abstract Objective Epilepsy surgery is known to be underutilized. Machine learning‐natural language processing (ML‐NLP) may able assist with identifying patients suitable for referral epilepsy evaluation. Methods Data were collected from two tertiary hospitals seen in neurology outpatients whom the diagnosis of “epilepsy” was mentioned. Individual case note review undertaken characterize nature diagnoses discussed these notes, and whether those fulfilled prespecified criteria workup (namely...
Abstract BACKGROUND Infliximab, an anti-tumor necrosis factor-alpha (TNF-α) agent, is well-established as salvage therapy in hospitalized patients with acute severe ulcerative colitis (ASUC) who do not respond to intravenous (IV) corticosteroids. Furthermore, obesity rates among inflammatory bowel disease (IBD) are increasing, and it unknown how impacts treatment response this setting. It has been postulated that obese individuals (Body Mass Index ≥30.0 kg/m²) may have decreased infliximab....
Article abstract—We report two cases of ictal vomiting in patients who had left temporal lobe epilepsy. In one patient, developed when the discharge spread to right as seen during depth electrode recording. second occurred with a restricted discharge, but patient was left-handed and right-hemisphere language dominance. These provide additional evidence involvement nondominant ictus emeticus.
Cannabidiol has shown efficacy in randomized clinical trials for drug-resistant epilepsy specific syndromes that predominantly affect children. However, high-level evidence the and safety of cannabidiol most common form adults, focal epilepsy, is lacking.To investigate efficacy, safety, tolerability transdermally administered adults with epilepsy.A randomized, double-blind, placebo-controlled, multicenter trial at 14 centers Australia New Zealand. Participants were receiving a stable regimen...
Conditioning methodologies associated with the psychology of learning are suggested as a new strategy to investigate behavior assassin bug Rhodnius prolixus, which is main vector Chagas disease in Venezuela. fourth leading cause death Latin America, it causes severe chronic illness and approximately 43,000 deaths per year. To illustrate this strategy, two preliminary experiments reported. In first, Pavlovian conditioning was examined by pairing an olfactory conditioned stimulus temperature...
Immune checkpoint inhibitor-related myositis should be considered in the differential diagnosis of patients presenting with acute weakness even if atezolizumab had been commenced many weeks beforehand.
This study provides contemporary data on patients admitted to a Neurology unit with seizures, the majority of whom have diagnosis epilepsy. There were 278 hospital presentations seizure during 6-month period, 60 admissions included for analysis. Provoking factors identified in 40%, poor medication adherence commonest precipitant. CT-brain had low diagnostic yield epilepsy presenting and should be reserved those further indications imaging. Patients drug-resistant comprised 54% suggesting...
Summary: Purpose: To evaluate the safety, tolerability, efficacy, and impact on quality of life gabapentin (Neurontin; GBP) as adjunctive therapy in patients with refractory partial seizures. Methods: AUS‐STEPS was an open‐label, multicenter, prospective study experiencing seizures who were inadequately controlled one to three concurrent antiepileptic drugs (AEDs). GBP treatment titrated a maximum 4,800 mg/day, over period 24 weeks, achieve efficacious tolerable dosage. Efficacy assessed by...
Infliximab is an anti-tumour necrosis factor agent used in the treatment of inflammatory bowel disease (IBD), which includes Crohn's and ulcerative colitis. While use infliximab well established IBD, there are now four recently FDA-approved biosimilars that increasingly due to their cost-benefit for patients, institutions payors. In addition, shortening length infusions from 120 min (standard infusion) 60 or less (rapid has been shown safely provide further while also improving patient...
Objective To present four patients seen over a five-year period who developed severe protracted encephalitic illnesses but whose outcomes were favourable. Clinical features Of the patients, aged 18, 22, 34 and 19, three presented with acute psychosis, all had prolonged clinical course requiring intensive care management. One patient residual generalised seizures other recovered fully. No infective or toxic agent could be identified viral encephalitis was considered most likely. Outcome...
ABSTRACT We report the case of a patient with benign refractory esophagojejunal anastomotic stricture for which 20-mm lumen-apposing metal stent was placed, resulting in fatal aortoenteric fistula. this to alert others potential complication LAMS placement esophageal strictures and recommend caution when using similar settings.