A5089727435- Blood disorders and treatments
- Regulation of Appetite and Obesity
- Schizophrenia research and treatment
- Pathogenesis and Treatment of Hiccups
- Diabetes Treatment and Management
- Neurotransmitter Receptor Influence on Behavior
Rigshospitalet
2022
BackgroundAlcohol use disorder (AUD) is a chronic, relapsing brain that accounts for 5% of deaths annually, and there an urgent need to develop new targets therapeutic intervention. The glucagon-like peptide-1 (GLP-1) receptor agonist exenatide reduces alcohol consumption in rodents nonhuman primates, but its efficacy patients with AUD unknown.MethodsIn randomized, double-blinded, placebo-controlled clinical trial, treatment-seeking were assigned receive (2 mg subcutaneously) or placebo once...
The antipsychotic drug clozapine remains underutilized partly because of the risk life-threatening adverse effects, such as neutropenia. Therefore, an extensive hematological monitoring program was set up to detect neutropenia.In this retrospective cohort study, we used registry-based data from Capital Region Denmark investigate incidence rates neutropenia among patients with a diagnosis schizophrenia or other psychotic disorders and treated for first time. In within-subject design, compared...