A5086459548- Alcohol Consumption and Health Effects
- Liver Disease Diagnosis and Treatment
- Substance Abuse Treatment and Outcomes
- Liver Disease and Transplantation
- Homelessness and Social Issues
- Education, Healthcare and Sociology Research
- Growth Hormone and Insulin-like Growth Factors
- Nutritional Studies and Diet
- Research in Social Sciences
- Pancreatitis Pathology and Treatment
- Employment and Welfare Studies
- Diet and metabolism studies
- Alcoholism and Thiamine Deficiency
- Health Promotion and Cardiovascular Prevention
- Pancreatic and Hepatic Oncology Research
- Prenatal Substance Exposure Effects
- Cerebrovascular and Carotid Artery Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Workplace Health and Well-being
- X-ray Diffraction in Crystallography
- Gastrointestinal disorders and treatments
- Liver Diseases and Immunity
- Birth, Development, and Health
- Crystallization and Solubility Studies
- Diet, Metabolism, and Disease
University of Southern Denmark
2016-2025
Hvidovre Hospital
2013-2023
Danish National Institute of Public Health
2008-2023
University of Copenhagen
2004-2022
Copenhagen University Hospital
2011-2022
Technische Universität Braunschweig
2016
University Hospital Cologne
2014
Becker Technologies (Germany)
2013
University of Kansas Medical Center
2011
Amager Hospital
2001-2011
The association between self-reported alcohol intake and the risk of future liver disease was studied in a large population-based prospective cohort with 12-year follow-up. Alcohol assessed 13,285 men women aged 30 to 79 years by self-administered questionnaire. Diagnoses indicating alcohol-induced (n − 261) or cirrhosis 124) were obtained from death certificates hospital discharge register, data analyzed multiplicative Poisson regression models. total cumulated observation time 130,558...
To examine the association between intake of different types alcoholic drinks and mortality.Prospective population study with baseline assessment alcohol intake, smoking habit, income, education, body mass index, 10-12 years' follow up mortality.Copenhagen city heart study, Denmark.6051 men 7234 women aged 30-70 years.Number time cause-specific deaths from 1976 to 1988.The risk dying steadily decreased an increasing wine--from a relative 1.00 for subjects who never drank wine 0.51 (95%...
BackgroundAlcohol use disorder (AUD) is a chronic, relapsing brain that accounts for 5% of deaths annually, and there an urgent need to develop new targets therapeutic intervention. The glucagon-like peptide-1 (GLP-1) receptor agonist exenatide reduces alcohol consumption in rodents nonhuman primates, but its efficacy patients with AUD unknown.MethodsIn randomized, double-blinded, placebo-controlled clinical trial, treatment-seeking were assigned receive (2 mg subcutaneously) or placebo once...
Objective: To examine the relation between different types of alcoholic drinks and upper digestive tract cancers (oropharyngeal oesophageal). Design: Population based study with baseline assessment intake beer, wine, spirits, smoking habits, educational level, 2-19 years' follow up on risk cancer. Setting: Denmark. Subjects: 15 117 men 13 063 women aged 20 to 98 years. Main outcome measure: Number time identification incident cancer during up. Results: During a mean 13.5 years, 156 subjects...
<h3>Abstract</h3> <b>Objective</b> : To examine the association between self reported alcohol intake and subsequent mortality from all causes if effect of on risk death is modified by sex, age, body mass index, smoking. <b>Design</b> Prospective population study with baseline assessment tobacco consumption 10-12 years9 follow up mortality. <b>Setting</b> Copenhagen city heart study, Denmark. <b>Subjects</b> 7234 women 6051 men aged 30-79 years. <b>Main outcome measure</b> Number time deaths...
Objective. There is increasing focus on non-alcoholic fatty liver disease (NAFLD). The aim of the present study was to conduct a long-term clinical follow-up patients with biopsy-confirmed without inflammation or significant fibrosis (pure liver), analyse for potential risk factors at time index biopsy important survival and development cirrhosis describe causes death. Material methods. Patients were linked through their personal identification number Danish National Registry Register Causes...
<h3>Background</h3> Alcohol and gallstone disease are the most established risk factors for pancreatitis. Smoking is rarely considered to be a cause despite fact that few studies have indicated opposite. We aimed assess independent effects of smoking on <h3>Methods</h3> used data from an observational, population-based cohort study conducted in Denmark. Participants were 9573 women 8332 men who followed up mean 20.2 years. underwent physical examination completed self-administered...
Knowledge of the natural course acute pancreatitis (AP) and risk progression to chronic (CP) is limited. The aims were describe: (1) incidence from AP CP, (2) prognostic factors for progression, (3) mortality progressive AP.During 1977 1982, patients admitted hospitals in Copenhagen with a diagnosis or CP included prospective cohort followed up by Danish registries 2008. subcohort analyses comprised 352 patients.Progressive was found 85 (24.1%) during follow-up; 48.2% developed alcoholic AP,...
Although there is a well-known relationship between total alcohol intake and future risk for cirrhosis, other factors such as the type of consumed are sparsely studied. The aim this study was to assess effects wine compared with types alcoholic beverages on alcohol-induced cirrhosis. In 3 prospective studies, 30,630 participants from Copenhagen area were followed-up observation time 417,325 person-years. Information weekly beer, wine, spirits, sex, age, body mass index, smoking habits,...
OBJECTIVE—To assess the prevalence of diabetes and impaired glucose tolerance (IGT) among Inuit population Greenland to determine risk factors for developing intolerance. RESEARCH DESIGN AND METHODS—This cross-sectional study included 917 randomly selected adult subjects living in three areas Greenland. Diabetes IGT were diagnosed using oral test. BMI waist-to-hip ratio measured blood samples taken from each subject. Sociodemographic characteristics investigated a questionnaire. RESULTS—The...
Cirrhotic patients exhibit a hyperdynamic and hyporeactive circulation with central hypovolaemia which may influence the course of disease. As terlipressin, vasopressin analogue, modify systemic haemodynamics in these patients, aim present study was to assess acute effects terlipressin on haemodynamics.Sixteen alcoholic cirrhosis portal hypertension had their systemic, central, splanchnic determined at baseline after blind randomised bolus infusion (2 mg) terlipressin/placebo.After arterial...
The association between alcohol intake and pancreatitis has been examined previously in case-control studies, mostly consisting of men. significance beverage type drinking pattern is unknown. objective this study was to assess the amount, type, frequency risk pancreatitis. For purpose, authors used data on 17,905 men women who participated Copenhagen City Heart Study 1976–1978, 1981–1983, 1991–1994, 2001–2003 Copenhagen, Denmark. Alcohol covariates were assessed by questionnaire. Information...
Objective. Alcohol is the most acknowledged risk factor for liver cirrhosis. Smoking rarely considered to be a cause of cirrhosis even though few studies have suggested opposite. The aim this study was assess independent effect smoking on alcoholic and in general. Materials methods. authors used data from Copenhagen City Heart Study including cohort 9889 women 8590 men Danish general population. covariates were assessed at four consecutive examinations 1976–78, 1981–83, 1991–94 2001–03....
Alcohol consumption has been associated with an increased risk of lung cancer, but the antioxidants in wine may, theory, provide protection. This association was studied 28, 160 men and women subjects from three prospective studies conducted 1964–1992 Copenhagen, Denmark. After adjustment for age, smoking, education, a low to moderate alcohol intake (1–20 drinks per week) not cancer. Men who consumed 21–41 more than 41 week had relative risks 1.23 (95% confidence interval (Cl) 0.88–1.74)...
Carbohydrate‐deficient transferrin (CDT) was analyzed by a modified radioimmunoassay test in random population sample of 400 individuals, and results were compared with reported alcohol intake derived from structured questionnaire. Among the 180 men, found to be acceptable respect detecting harmful (<35 beverages/week) above recommended level (21 beverages/week), although positive predictive values low. 220 women, invalid low values. CDT other known markers high intake, it observed that...