A5103052663- Infant Nutrition and Health
- Hepatitis C virus research
- Neonatal Respiratory Health Research
- Clinical Nutrition and Gastroenterology
- Infant Development and Preterm Care
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Neonatal and fetal brain pathology
- Gestational Diabetes Research and Management
- Platelet Disorders and Treatments
- Blood Coagulation and Thrombosis Mechanisms
- Homelessness and Social Issues
- Liver Disease Diagnosis and Treatment
- Vaccine Coverage and Hesitancy
- Effects and risks of endocrine disrupting chemicals
- Influenza Virus Research Studies
- Prenatal Substance Exposure Effects
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pharmaceutical studies and practices
- Gut microbiota and health
- SARS-CoV-2 and COVID-19 Research
- Anesthesia and Neurotoxicity Research
- Child Nutrition and Feeding Issues
- Biochemical and Molecular Research
Sapienza University of Rome
2021-2024
Policlinico Umberto I
2023-2024
John Wiley & Sons (United Kingdom)
2019
Hudson Institute
2019
Vaccine-induced thrombotic thrombocytopenia with cerebral venous thrombosis is a syndrome recently described in young adults within two weeks from the first dose of ChAdOx1 nCoV-19 vaccine. Here we report cases malignant middle artery (MCA) infarct and 9-10 days following vaccination. The arrived our facility around same time but different geographical areas, potentially excluding epidemiological links; meanwhile, no abnormality was found respective vaccine batches. Patient 1 57-year-old...
Fetal alcohol spectrum disorder (FASD) is a set of conditions resulting from prenatal exposure (PAE). FASD estimated to affect between 2% and 5% people in the United States Western Europe. The exact teratogenic mechanism on fetal development still unclear. Ethanol (EtOH) contributes malfunctioning neurological system children exposed utero by decreasing glutathione peroxidase action, with an increase production reactive oxygen species (ROS), which causes oxidative stress. We report case...
Background: Recommended vaccinations are the cheapest and most effective measure to reduce risk of transmission related complications, especially in high-risk healthcare settings. This study aimed evaluate knowledge, attitudes behaviours HCWs relation national recommendations. Methods: A transversal was conducted through administration a questionnaire by personal interview. The following care units were involved: Paediatric, Neonatal, Cardiac Surgery General Intensive Care Units Infectious...
Microbiota plays a crucial role in intestinal maturation preterm newborns. The clinical manifestation of the immaturity gastro-intestinal tract is called feeding intolerance (FI). This condition may resolve spontaneously or dramatically evolve into necrotizing enterocolitis. One most challenging tasks for neonatologist to identify those neonates that will develop disease early order adequately provide nutrition these patients, from very first hours life. A close interplay between maturity...
Nutrition in early life has an impact on white matter (WM) development preterm-born babies. Quantitative analysis of pixel brightness intensity (PBI) cranial ultrasound (CUS) scans shown a great potential the evaluation periventricular WM echogenicity preterm newborns. We aimed to investigate employment this technique objectively verify effects parenteral nutrition (PN) damage infants. Prospective observational study including newborns with gestational age at birth ≤32 weeks and/or weight...
Positive effects of early nutritional strategies on neurological outcomes have been observed when nutrients were administered by the enteral route, especially during first week life. Evidence reports that serum neurofilament light chain (NfL), a structural protein neurons, is specific and reliable biomarker neuronal damage.
(1) Background: An increased protein intake via parenteral nutrition (PN) in early life is associated with an improvement of the nitrogen balance preterm newborns. However, role energy on amino acid (AA) utilization provided by PN remains to be defined. We investigated effects blood AA levels and profiles. (2) Methods: Quasi-experimental study including very low birth weight newborns who received enhanced (Cohort A) or standard B), a similar amount first week life. Blood were measured...
Abstract Non-cystic white matter (WM) injury has become prevalent among preterm newborns and is associated with long-term neurodevelopmental impairment. Magnetic resonance the gold-standard for diagnosis; however, cranial ultrasound (CUS) more easily available but limited by subjective interpretation of images. To overcome this problem, we enrolled in a prospective observational study, patients gestational age at birth < 32 weeks normal CUS scans or grade 1 WM injury. Patients underwent...
Hyperglycemia (HG) is an independent risk factor of mortality and morbidity in very low birth weight newborns (VLBW). Achievement high nutritional intakes the first days life (DoL) by parenteral nutrition (PN) increases HG. We aim to assess if a delayed achievement PN macronutrient target dose could reduce occurrence HG VLBW. enrolled 353 VLBW neonates randomized controlled clinical trial comparing two protocols that differed timing energy amino acid achievement: (1) early (energy within 4–5...
Risultati: su 120000 unità testate, 80 sono risultate RR per HCV-Ab e 57 HIV1/2-Ab.Al test HCV-RIBA 42 donatori/80 stati confermati positivi 30 erano anche viremici (71%), 20/80 hanno dato esito indeterminato (15% NAT+), 18/80 negativi RIBA/NAT.24 campioni RIBA/NAT con ALT elevate presentavano uno score di 4+ nel 100% dei casi la c33 c22, nell'87% c100 solo 50% l'NS5.I RIBA indeterminati/NAT esprimono Ab anti-c33 o -c22, 4+/3+.Con un pattern espressione sovrapponibile i NAT presentano bassi...