- Ocular Diseases and Behçet’s Syndrome
- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Inflammatory Myopathies and Dermatomyositis
- Sarcoidosis and Beryllium Toxicity Research
- Systemic Sclerosis and Related Diseases
- Retinal and Optic Conditions
- Eosinophilic Disorders and Syndromes
- Autoimmune and Inflammatory Disorders
- Dermatological and Skeletal Disorders
- Venous Thromboembolism Diagnosis and Management
- IgG4-Related and Inflammatory Diseases
- Autoimmune Bullous Skin Diseases
- Autoimmune and Inflammatory Disorders Research
- Salivary Gland Disorders and Functions
- Skin Diseases and Diabetes
- Otitis Media and Relapsing Polychondritis
- Infectious Diseases and Tuberculosis
- Peripheral Neuropathies and Disorders
- Renal Diseases and Glomerulopathies
- Celiac Disease Research and Management
- Urticaria and Related Conditions
- Musculoskeletal synovial abnormalities and treatments
- Rheumatoid Arthritis Research and Therapies
- Vascular Anomalies and Treatments
Hopital Universitaire Hedi Chaker
2016-2025
University of Sfax
2006-2025
Faculty of Medicine of Sfax
2025
General Department of Preventive Medicine
2023
Tumori Foundation
2021
Hopital Universitaire Habib Bourguiba
2005-2014
Institut de Myologie
2009
Assistance Publique – Hôpitaux de Paris
2009
To assess the safety and efficacy of TNF-α antagonists tocilizumab in patients with Takayasu arteritis (TAK). A total 209 TAK [median age 29 years (interquartile range 7-62)], 186 (89%) females] were included. They received either [n = 132 (63%) 172 lines; infliximab (n 109), adalimumab 45), golimumab 8), certolizumab 6) etanercept 5)] or 77 (37%) 121 i.v. s.c. 95 26 cases, respectively]. complete response at 6 months was evidenced 101/152 (66%) on 75/107 (70%) tocilizumab. Age ≥30 [odds...
Hereditary haemorrhagic telangiectasia is a rare disease characterized by cutaneo-mucous and visceral arteriovenous malformations. Cardiac involvement uncommon was presented primarily hyper-output heart failure. Hemorrhagic pericardial effusion, although extremely rare, can occur during HHT. We report the case of 48-years-old woman which hospitalized in 2015 internal medicine department, Sfax, Tunisia for anicteric cholestasis. She noticed personnel familial history recurrent epistaxis....
Adult onset Still disease (AOSD) is a rare systemic auto inflammatory of unknown origin. It characterized by its clinical and biological polymorphism. Eliminating differential diagnoses one the most important steps when diagnosis adult Still’s suggested, given absence or laboratory signs to support diagnosis; so-called “diagnosis exclusion”. We conducted retrospective study describe features, treatment, course, complications AOSD in 65 Tunisian patients compare them literature. All responded...
<b>Introduction:</b> Cerebral sinus thrombosis is an uncommon neurologic condition caused by many etiologies. Behçet’s disease (BD) one of the leading causes in Mediterraneen and Middle Eastern countries. The aim our study was to summarize clinical manifestation, therapeutic strategies prognosis cerebral BD southern Tunisia.<br /> <b>Patients methods:</b> This a descriptive patients followed for complicated with department internal medicine Hedi Chaker Hospital...
Hughes-Stovin syndrome (HSS) is a systemic vasculitis characterized by widespread venous/arterial thrombosis and pulmonary artery aneurysms (PAAs), which associated with serious morbidity mortality. All fatalities reported in HSS resulted from unpredictable fatal suffocating hemoptysis. Therefore, it necessary to recognize complications at an early stage of the disease.The aims this study are develop reference atlas images depicting characteristic features computed tomography angiography...
In this large multicentre study, we compared the effectiveness and safety of tocilizumab intravenous versus subcutaneous (SC) in 109 Takayasu arteritis (TAK) patients.We conducted a retrospective study referral centres from France, Italy, Spain, Armenia, Israel, Japan, Tunisia Russia regarding biological-targeted therapies TAK, since January 2017 to September 2019.A total TAK patients received at least 3 months therapy were included study. Among them, 91 18 SC tocilizumab, respectively. A...
To describe the most common reasons of admission Tunisian patients with systemic lupus erythematosus (SLE) and outcomes these hospitalisations.The charts SLE who were hospitalised at our Department Internal Medicine during a 2-year period from January 2011 to December 2012 retrospectively reviewed, demographic characteristics, clinical laboratory features, as well all comorbidities, collected.There 128 episodes hospitalisation 87 SLE. 25 (28.7%) admitted twice or more. The median length stay...
Hughes and Stovin first reported a syndrome consisting of multiple pulmonary artery aneurysms venous thrombosis in 1959. Here, we encountered 42-year old woman who had hemoptysis revealing Hughes- syndrome. Helical computed tomography showed with thromboembolism. The patient was treated steroid therapy, cyclophosphamide anticoagulation good response.
Relapsing polychondritis (RP) is a rare disease involving cartilaginous structures, predominantly the ears, nose and laryngotracheobronchial tree. The eyes, cardiovascular system, peripheral joints, skin, central nervous system may also be affected. Involvement of all ocular structures has been described. Non-granulomatous uveitis common feature; however hypopyon uncommon. We herein present case 42-year-old man who had diagnosed with bronchial asthma for long period; presented recurrent as...
Intracardiac thrombosis is an exceptional complication of Behçet's disease. The management this involvement difficult due to the risk recurrence. We present case a young man admitted our hospital for intermittent fever. microbiologic investigations did not show any causative germ. discovered right ventricle thrombus on echocardiography. confirmed diagnosis pulmonary embolism CT angiogram. patient developed oral and genital ulcerations which were consistent with syndrome. had disappeared...
Sexuality is an often neglected area in patients with rheumatic disease. The aim of this study to assess sexual functioning and quality life a group married women Systemic Sclerosis (SSc).This horizontal for descriptive analytical purposes. Married SSc were interviewed about their life.A total ten who met the criteria have accepted participate study. Their mean age was 52, 4± 8,2 years. Eight thought that disease had affected activity. All reported decrease frequency intercourse since onset...