A5100740495- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Nanoplatforms for cancer theranostics
- Peptidase Inhibition and Analysis
- Plant Molecular Biology Research
- Plant tissue culture and regeneration
- Supramolecular Self-Assembly in Materials
- Plant Reproductive Biology
- Plant-Microbe Interactions and Immunity
- Nanomaterials for catalytic reactions
- Leaf Properties and Growth Measurement
- Bryophyte Studies and Records
- Plant Physiology and Cultivation Studies
- Photosynthetic Processes and Mechanisms
- Supramolecular Chemistry and Complexes
- Luminescence and Fluorescent Materials
- Plant and Fungal Interactions Research
- Plant Diversity and Evolution
- Photodynamic Therapy Research Studies
- Copper-based nanomaterials and applications
- Plant Gene Expression Analysis
- Photoacoustic and Ultrasonic Imaging
- Advanced Sensor and Energy Harvesting Materials
- Polysaccharides and Plant Cell Walls
- Plant Virus Research Studies
National Institute of Metrology
2024
University of Chinese Academy of Sciences
2019-2023
State Key Laboratory of Plant Genomics
2022-2023
Institute of Genetics and Developmental Biology
2022-2023
Chinese Academy of Sciences
2022-2023
Research Institute of Forestry
2023
Chinese Academy of Forestry
2023
Baylor College of Medicine
2023
National Center for Nanoscience and Technology
2019-2021
Jiangsu Normal University
2021
Abstract Tumor complexity makes the development of highly sensitive tumor imaging probes an arduous task. Here, we construct a peptide‐based near‐infrared probe that is responsive to fibroblast activation protein‐α (FAP‐α), and specifically forms nanofibers on surface cancer‐associated fibroblasts (CAFs) in situ. The assembly/aggregation‐induced retention (AIR) effect results enhanced accumulation around tumor, resulting 5.5‐fold signal enhancement 48 h after administration compared control...
CINV1, converting sucrose into glucose and fructose, is a key entry of carbon cellular metabolism, HXK1 functions as pivotal sensor for glucose. Exogenous sugars trigger the Arabidopsis juvenile-to-adult phase transition via miR156A/SPL module. However, endogenous factors that regulate this process remain unclear. In study, we show specifically induced PAP1 transcription factor directly positively controls CINV1 activity. Furthermore, identify feed-forward loop...
Abstract Tumor complexity makes the development of highly sensitive tumor imaging probes an arduous task. Here, we construct a peptide‐based near‐infrared probe that is responsive to fibroblast activation protein‐α (FAP‐α), and specifically forms nanofibers on surface cancer‐associated fibroblasts (CAFs) in situ. The assembly/aggregation‐induced retention (AIR) effect results enhanced accumulation around tumor, resulting 5.5‐fold signal enhancement 48 h after administration compared control...
Leaves are crucial for maintaining plant growth and development via photosynthesis, their function is simultaneously regulated by a suite of phenotypic traits. Although much known about the genetic architecture individual leaf traits, unraveling basis complex morphology remains challenge. Based on functional correlation coordination multi-traits, we divided 15 morphological traits into three modules, comprising size (area, length, width, perimeter), shape (leaf lobes, aspect ratio,...
An intervention-induced infection, such as a catheter-associated is one of the most common nosocomial-acquired infections, which causes huge healthcare threats and costs to clinical treatment. This work developed thermosensitive hydrogel coating on polydimethylsiloxane (PDMS), smartly switched from hydrophilic lubrication antimicrobial antifouling properties. Upon optimization molar ratio N-isopropylacrylamide versus N,N′-methylenebis(2-propenamide) (NNMBA), exhibited 2.5-fold 4.4-fold...
Reactions of half-sandwich iridium and rhodium complexes [Cp*MCl2]2 (1a: M = Ir, 1b: Rh) the ruthenium complex [(p-cymene)RuCl2]2 (1c) with 4DPDS gave corresponding binuclear [{Cp*MCl2]2}(m-4DPDS) (2a: 2b: [{(p-cymene)RuCl2]2}(m-4DPDS) (2c), which can be converted into metallamacrocycles. The metallamacrocycles [Cp*M(m-4DPDS)Cl]2(2+) (3a: 3b: [(p-cymene)Ru(m-4DPDS)Cl]2(2+) (3c) are composed two units ligands same chirality. macrocycle 3c is chiral changes its shape slightly depending on...
Fagopyrum esculentum (Polygonaceae: Caryophyllales) exhibits an undifferentiated perianth comprising five showy tepals, which does not completely correspond to the differentiated into typical sepals and petals in most core eudicots. In Arabidopsis, APETALA1 (AP1) gene is involved specifying development. Here we isolated AP1 ortholog, FaesAP1, a 2.2kb FaesAP1 promoter (pFaesAP1) from F. esculentum. expression mainly detectable all floral organs maintains at high level when tepals elongate...
Pattern recognition receptors (PRRs) are plasma membrane-localised proteins that sense molecular patterns to initiate pattern-triggered immunity (PTI). Receptor-like cytoplasmic kinases (RLCKs) function downstream of PRRs propagate signal transduction via the phosphorylation substrate proteins. The identification and characterisation RLCK-regulated critical for our understanding plant immunity. We showed SHOU4 SHOU4L rapidly phosphorylated upon various elicitation indispensable resistance...
Inverse CeO₂-Co₃O₄/CuO catalysts with chrysanthemum-like morphology were prepared by the co-precipitation method, and characterized via scanning electron microscopy (SEM), transmission (TEM), X-ray diffraction (XRD), temperature-programmed reduction (H2-TPR), N2 adsorption-desorption techniques. It is found that filament composed of ordered-array CuO nanocrystallites, CeO₂ was dispersed on outer surface filament. The catalyst thin filaments can form long periphery at CeO₂-CuO contact...
Abstract In the delivery system, high‐performance targeting and local burst‐releasing of antibiotics enable enhancement antipathogen efficacy reduction drug‐resistance risk. Bacteria cell wall driven self‐disassembled nanovesicles (BSNs) composed a dense H‐aggregated cyanine bilayer are herein reported. The nanovesicle displays trigger‐disassembly turn‐on near infrared (NIR) fluorescence property activated by Gram‐positive bacteria. Mechanistic studies indicate that interaction between...
Cup-shaped cotyledon (CUC) gene is a kind of border-specific gene, which leaf edge cracking and complex leaflet development. CUC plays an important role in shoot apical meristem formation margin development Phoebe neurantha (Hemsl.) Gamble. In this paper, designated as PnCUC1 was successfully cloned from P. The full-length 1317-bp contained 1008-bp open reading frame. It encoded 335-amino-acid protein with calculated molecular weight about 37.8 kDa isoelectric point 7.04. Sequence comparison...
<div>Abstract<p>Leucine-rich repeat-containing G protein–coupled receptors 4, 5, and 6 (LGR4/5/6) play critical roles in development cancer. The widely accepted mechanism is that these proteins, together with their R-spondin ligands, stabilize Wnt receptors, thus potentiating signaling. Here we show LGR4 enhanced breast cancer cell metastasis even when signaling was deactivated pharmacologically or genetically. Furthermore, mutants cannot potentiate nevertheless promoted...