A5039621451- Parathyroid Disorders and Treatments
- Vitamin K Research Studies
- COVID-19 Clinical Research Studies
- Pharmacological Effects and Toxicity Studies
- Vitamin D Research Studies
- Dialysis and Renal Disease Management
- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Biomedical Research and Pathophysiology
- Potassium and Related Disorders
- Muscle and Compartmental Disorders
- Folate and B Vitamins Research
- Vitamin C and Antioxidants Research
- Ion Transport and Channel Regulation
- Adolescent and Pediatric Healthcare
- Diabetes Treatment and Management
- Long-Term Effects of COVID-19
- Renal Diseases and Glomerulopathies
- Multiple Myeloma Research and Treatments
- Magnesium in Health and Disease
- Chemotherapy-induced organ toxicity mitigation
- Alkaline Phosphatase Research Studies
- TGF-β signaling in diseases
- Apelin-related biomedical research
University of Bologna
2017-2024
Ospedale Infermi di Rimini
2022-2023
Azienda USL di Bologna
2021-2023
Azienda Unità Sanitaria Locale Della Romagna
2022
Istituti di Ricovero e Cura a Carattere Scientifico
2020
Policlinico S.Orsola-Malpighi
2017-2020
March of Dimes
2017
ABSTRACT Background Chronic kidney disease mineral bone disorder (CKD-MBD) is a condition characterized by alterations of calcium, phosphate, parathyroid hormone (PTH), and fibroblast growth factor 23 (FGF-23) metabolism that in turn promote disorders, vascular calcifications, increase cardiovascular (CV) risk. Nephrologists’ awareness diagnostic, prognostic, therapeutic tools to manage CKD-MBD plays primary role adequately preventing managing this clinical practice. Methods A national...
Abstract Background CPFA is an extracorporeal treatment used in severe sepsis to remove circulating proinflammatory cytokines. Limited evidence exists on the effectiveness of bilirubin adsorption by hydrophobic styrenic resin, distinctive part CPFA. The aim this study validate liver detoxification. Methods In prospective observational study, we enrolled patients with acute or acute-on-chronic failure (serum total > 20 mg/dL MELD Score 20) hospitalized from June 2013 November 2017. was...
Hemodialysis (HD) is known to trigger a chronic inflammatory status, affecting the innate and acquired immune response. This study was aimed at comparative analysis of cell subsets, proliferation, apoptosis in subjects receiving HD treatment with respect healthy control. Regardless dialysis filter used, we observed reshaping component both patients between various sessions treatment, an impairment CD3 cells, along increase CD4 CD8 populations producing pro-inflammatory factors such as IL-17...
Withdrawal statement This manuscript has been withdrawn after a request from the Dean of Department Medical and Surgical Sciences (DIMEC) at University Bologna. constitutes fraudulent submission by third party impersonating Prof. Gaetano La Manna said university. The email address listed for corresponding author is invalid not institutional Manna, member DIMEC. Additionally, there are no other faculty members or researchers named employed Bologna (UNIBO). Furthermore, department (DIMES)...
Introduction: High-flux hemodialysis membranes may modulate the cytokine storm of SARS-CoV-2, but their impact on chronic (CHD) patients is unknown. The aim study was evaluation asymmetric cellulose triacetate (ATA) and polymethylmethacrylate (PMMA) dialyzers inflammatory markers clinical outcomes in CHD with SARS-CoV-2. Methods: A prospective, observational SARS-CoV-2 carried out. Patients were enrolled from March 2020 to May 2021. Pre- postdialysis C-reactive protein (CRP), procalcitonin...
Fractures and vascular calcifications (VCs) are common in patients with chronic kidney disease (CKD). They related to abnormalities vitamin D metabolism, calcium, phosphorus, parathyroid hormone, fibroblast growth factor 23 (FGF23)/Klotho that occur CKD. Impaired metabolism abnormal levels of phosphate, hormone (PTH), FGF23/Klotho drive bone changes It is unclear if oral calcitriol safely mitigates fracture risk without increasing the burden calcifications. Therefore, we investigated whether...
Abstract Background Restless legs syndrome (RLS) is characterized by an urge to move the extremities, accompanied paraesthesiae, in evening and at night. Uraemic RLS, a type of secondary occurs commonly chronic kidney disease end-stage renal disease. Progression uraemic RLS over time unclear. Therefore we investigated prevalence, progression time, risk factors impact on survival cohort dialysis patients. Methods We reviewed 7-year follow-up haemodialysis (HD) patients had previously for...
Vascular calcification and fragility fractures are associated with high morbidity mortality, especially in end-stage renal disease. We evaluated the relationship of iliac arteries calcifications (IACs) abdominal aortic (AACs) risk for vertebral (VFs) hemodialysis patients. The VIKI study was a multicenter cross-sectional involving 387 biochemical data included bone health markers, such as vitamin K levels, K-dependent proteins, 25(OH)D, alkaline phosphatase, parathormone, calcium, phosphate....
Supra hemodiafiltration with reinfusion of the endogenous ultrafiltrate (Supra-HFR) is a dialysis technique used to improve uremic toxin removal in range middle molecular weight molecules. Supra-HFR does not require preparation and online infusion high-purity water because it allows production an that undergoes detoxification through adsorbing resin.We investigated ability remove fibroblast growth factor 23 (FGF23), interleukin 6 (IL-6), tumor necrosis alpha (TNF-alpha), 8 (IL-8),...
Objective: Kidney transplant survival in the first year after transplantation has significantly improved, although long-term results are less encouraging. In recent years pressure on scientific community need to refine methods discover possible factors that can predict graft 10, 20 or more is increased. Few previous studies have evaluated patient and laboratory characteristics associated with optimal survival. The objective of this study was identify transplanted kidney very long term....
Chronic hemodialysis patients are at high risk of severe COVID-19 disease and death related to the infection. Anti-spike monoclonal antibodies administration reduces progression hospitalization in high-risk subjects but no clear data on end-stage renal available. We report 2 cases Bamlanivimab/Etesevimab two not hospitalized chronic with SARS-CoV2 Since they large molecules (human immunoglobulin G1) molecular weight 146,000 Da, was conducted during second hour dialysis session adverse...