- Renal Diseases and Glomerulopathies
- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Complement system in diseases
- Muscle and Compartmental Disorders
- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Blood Pressure and Hypertension Studies
- Vascular Procedures and Complications
- Pregnancy and Medication Impact
- Central Venous Catheters and Hemodialysis
- Ethics and Legal Issues in Pediatric Healthcare
- Lysosomal Storage Disorders Research
- Birth, Development, and Health
- Trypanosoma species research and implications
- Cellular transport and secretion
Istituti di Ricovero e Cura a Carattere Scientifico
2022-2024
University of Bologna
2022-2024
Azienda USL di Bologna
2023-2024
Policlinico S.Orsola-Malpighi
2022
Nephrology is an ever-evolving field of medicine. The importance such a discipline related to the high clinical impact kidney disease. In fact, abnormalities function and/or structure are common in general population, reaching overall prevalence about 10%. More importantly, onset damage strikingly risk cardiovascular events, mortality, and progression failure which, turn, compromises quality duration life. Attempts comprehend pathogenesis molecular mechanisms involved disease occurrence have...
Abstract IgA Nephropathy (IgAN) is the most prevalent glomerular disease worldwide. Complement system activation crucial in its pathogenesis. Few studies correlated serum C3 and C4 with activity prognosis. This retrospective study investigated prognostic value of complement at time diagnosis patients IgAN. Specifically we evaluated whether adding levels to established predictive models-one based on variables related chronic kidney (CKD) progression another incorporating from International...
Abstract Background and Aims IgA Nephropathy (IgAN) is the most common glomerular disease worldwide [1]. Complement system activation through alternative lectin pathways crucial in its pathogenesis leads to worse outcome, eliciting need for (new) biomarkers assess risk of progression potential response new targeted treatments [2, 3]. Only few works have correlated serum C3 C4 with activity prognosis [4, 5]. Our work explores advantages incorporating levels into a standardized prognostic...
Introduction: High-flux hemodialysis membranes may modulate the cytokine storm of SARS-CoV-2, but their impact on chronic (CHD) patients is unknown. The aim study was evaluation asymmetric cellulose triacetate (ATA) and polymethylmethacrylate (PMMA) dialyzers inflammatory markers clinical outcomes in CHD with SARS-CoV-2. Methods: A prospective, observational SARS-CoV-2 carried out. Patients were enrolled from March 2020 to May 2021. Pre- postdialysis C-reactive protein (CRP), procalcitonin...
<title>Abstract</title> Background. Evaluating the impact of C3 glomerulopathy (C3G) on quality life (QoL) and its humanistic burden is critical to a deeper understanding condition in clinical practice. This Narrative Medicine (NM) project collected C3G narratives investigate QoL challenges associated with gain insights for more profound knowledge this disease. Methods. The was conducted Italy from January October 2023 involved eight hospital-based centres two patient associations. Illness...
<title>Abstract</title> <bold>Introduction</bold> IgA Nephropathy (IgAN) is the prevalent glomerular disease worldwide. Complement system activation crucial in its pathogenesis. Few studies correlated serum C3 and C4 with activity prognosis. <bold>Methods</bold> This retrospective monocentric study investigated prognostic value of complement patients IgAN. Primary outcome was defined as 40% decline eGFR or onset kidney failure. The aim to evaluate whether addition established predictive...
Abstract BACKGROUND AND AIMS High flux haemodialysis membranes may modulate the cytokine storm of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but their impact in chronic (CHD) patients is not assessed [1, 2]. The aim study was evaluation asymmetric cellulose triacetate (ATA) and polymethylmethacrylate (PMMA) dialyzers on inflammatory markers CHD with SARS-CoV-2. METHOD A prospective, observational (age ≥18 years) affected by SARS-CoV-2 carried out. Patients were enrolled...
Abstract BACKGROUND AND AIMS Arteriovenous fistula (AVF) must be the first choice where eligible and a prompt approach within 48–72 h should performed in case of acute AVF failure order to maintain patency vascular access. Evaluation most appropriate de-clotting technique made considering patient's comorbidity, characteristics absolute, relative temporary contraindications each kind corrective intervention. The outcome is different between multiple methods nowadays mechanical...