A5012289180- Ginseng Biological Effects and Applications
- Skin Protection and Aging
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- melanin and skin pigmentation
- Natural product bioactivities and synthesis
- Polysaccharides and Plant Cell Walls
- Medical Research and Treatments
- Essential Oils and Antimicrobial Activity
- NF-κB Signaling Pathways
- Plant Molecular Biology Research
- Sepsis Diagnosis and Treatment
- Genomics, phytochemicals, and oxidative stress
- Cell death mechanisms and regulation
- Herbal Medicine Research Studies
- Food Allergy and Anaphylaxis Research
- Morinda citrifolia extract uses
- Advanced Glycation End Products research
- Allergic Rhinitis and Sensitization
- Pancreatitis Pathology and Treatment
- Medicinal Plant Research
- Plant Stress Responses and Tolerance
- Sirtuins and Resveratrol in Medicine
- Phytochemistry and biological activity of medicinal plants
- Ethnobotanical and Medicinal Plants Studies
Sungkyunkwan University
2020-2025
Huaiyin Normal University
2016-2024
Yonsei University
2018
Hunan Agricultural University
2013
Guangdong Medical College
2004
Wheat bran-derived polysaccharides have attracted particular attention due to their immunomodulatory effects. However, the molecular mechanisms underlying functions are poorly understood. The current study was designed examine effect of wheat bran polysaccharide (WBP) on RAW 264.7 cells and signaling pathways, which not been explored. In addition, we also investigated immuno-enhancement effects WBP cyclophosphamide (CTX)-induced immunosuppression in mice. significantly increased...
Quercetin 3-O-β-D-glucuronide (Q-3-G), the glucuronide conjugate of quercetin, has been reported as having anti-inflammatory properties in lipopolysaccharide-stimulated macrophages, well anticancer and antioxidant properties. Unlike which extensively described to possess a wide range pharmacological activities including skin protective effects, benefits mechanisms Q-3-G remained be elucidated. This study focused on characterizing properties, against UVB-induced or H2O2-induced oxidative...
Protopanaxatriol (PPT) is a secondary intestinal metabolite of ginsenoside in ginseng. Although the effects PPT have been reported various diseases including cancer, diabetes and inflammatory diseases, skin protective are poorly understood.HaCaT cells were treated with dose-dependent manner. mRNA protein levels which related to barrier hydration detected compared retinol. Luciferase assay was performed explore relative signaling pathway. Western blot conducted confirm these pathways...
Chloranthalactone B (CTB), a lindenane-type sesquiterpenoid, was obtained from the Chinese medicinal herb Sarcandra glabra, which is frequently used as remedy for inflammatory diseases. However, anti-inflammatory mechanisms of CTB have not been fully elucidated. In this study, we investigated molecular underlying these effects in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. strongly inhibited production nitric oxide and pro-inflammatory mediators such prostaglandin E2, tumor...
Ardisia silvestris is a traditional medicinal herb used in Vietnam and several other countries. However, the skin-protective properties of A. ethanol extract (As-EE) have not been evaluated. Human keratinocytes form outermost barrier skin are main target ultraviolet (UV) radiation. UV exposure causes photoaging via production reactive oxygen species. Protection from thus key component dermatological cosmetic products. In this research, we found that As-EE can prevent UV-induced aging cell...
Maintaining skin homeostasis is one of the most important factors for health. UVB-induced photoaging a difficult problem that has negative impacts on homeostasis. So far, number compounds have been discovered improve human barrier function and hydration, are thought to be effective ways protect
Two-year-old seedlings of trifoliate orange (Poncirus trifoliata (L.) Raf.) and lemon (Citrus limonia Osbeck.) were sprayed with 0.1 mmol.L-1 abscisic acid (ABA) then their leaves collected randomly to expose freezing stress. Specifically, these detached treated at 0, -3, -6, -9 -12°C for 1 h respectively.The concentration malondialdehyde (MDA), percentage electrolyte leakage (EL) the activities several antioxidant enzymes (superoxide dismutase, catalase peroxidase) determined...
Grewia tomentosa Juss. is a deciduous shrub that mainly grows in Asia. Despite studies of other species for treatment various diseases, has not been studied as medicinal herb. This study evaluates the anti-allergic and anti-topic dermatitis activity ethanol extract (Gt-EE). The results show Gt-EE suppressed IgE-antigen-induced β-hexosaminidase release. mRNA expression IL-1β, IL-4, IL-5, IL-6, IL-13, TNF-α, MCP-1, TSLP, which are involved allergic responses, was inhibited by IgE-stimulated...
Upregulation of human telomerase reverse transcriptase (hTERT) expression is an important factor in the cellular survival and cancer. Although growing evidence suggests that hTERT inhibits apoptosis by telomere-independent functions, mechanisms involved are not fully understood. Here, we show contains a BH3-like motif, short peptide sequence found BCL-2 family proteins, interacts with anti-apoptotic proteins MCL-1 BCL-xL, suggesting functional link between mitochondrial pathway apoptosis....
The Licania genus has been used in the treatment of dysentery, diabetes, inflammation, and diarrhea South America. Of these plants, strong anti-inflammatory activity macrocarpa Cuatrec (Chrysobalanaceae) reported previously. However, beneficial activities this plant on skin health have remained unclear. This study explores protective a methanol extract (50-100 μg/mL) aerial parts L. (Lm-ME) its mechanism, terms moisturizing/hydration factors, wrinkles, UV radiation-induced cell damage,...
Ginsenoside F2 (GF2), a minor component of Panax ginseng, has been reported to possess wide variety pharmacological activities. However, its effects on glucose metabolism have not yet reported. Here, we investigated the underlying signaling pathways involved in hepatic glucose. HepG2 cells were used establish insulin-resistant (IR) model and treated with GF2. Cell viability uptake-related genes also examined by real-time PCR immunoblots. assays showed that GF2 up 50 μM did affect normal...
Objective To investigate an effective method to treat gastric ulcer perforation with integrated traditional Chinese and western medicine. Methods 117 patients were randomly divided into a treatment group control group.The was treated acupuncture plus Sanbal Powder, the conventional medicine exclusively. Results The two groups showed significant difference in cure rate, total efficiency, average inpatient free, relapse rate three years P＜0.01. Conclusion therapy of will shorten time,...
Objective To investigate the treatment of postoperative gastric fistula with combined traditional Chinese and western medicine.Methods Altogether 56 cases ofgastric after gastrectomy were randomly divided into a group control group.The was simply treated conventional medicine therapy,while self-made compound Wubei powder scattered gelatin sponge plugging in addition to treatment.Results The effective rate 96.4% 64.8% respectively.The significant better than (p＜0.01).Conclusion therapy can...