A5044864981- Advanced biosensing and bioanalysis techniques
- Crystallization and Solubility Studies
- Biosensors and Analytical Detection
- X-ray Diffraction in Crystallography
- Analytical Chemistry and Sensors
- Electrochemical Analysis and Applications
- Electrochemical sensors and biosensors
- Advanced Chemical Sensor Technologies
- Conducting polymers and applications
- Metal complexes synthesis and properties
- Crystallography and molecular interactions
- SARS-CoV-2 detection and testing
- CRISPR and Genetic Engineering
- Magnetism in coordination complexes
- Celiac Disease Research and Management
- RNA and protein synthesis mechanisms
- Advanced Biosensing Techniques and Applications
- DNA and Nucleic Acid Chemistry
- Acoustic Wave Resonator Technologies
- Identification and Quantification in Food
- Organometallic Complex Synthesis and Catalysis
- Analytical Chemistry and Chromatography
- Molecular Sensors and Ion Detection
- Synthesis and Characterization of Heterocyclic Compounds
- Gas Sensing Nanomaterials and Sensors
University of Parma
2016-2025
Istituto Nazionale Biostrutture e Biosistemi
2024
University of Messina
1999
Efficient and timely testing has taken center stage in the management, control, monitoring of current COVID-19 pandemic. Simple, rapid, cost-effective diagnostics are needed that can complement polymerase chain reaction-based methods lateral flow immunoassays. Here, we report development an electrochemical sensing platform based on single-walled carbon nanotube screen-printed electrodes (SWCNT-SPEs) functionalized with a redox-tagged DNA aptamer specifically binds to receptor binding domain...
Abstract Point‐of‐care technologies need particularly stringent requirements, including portability, rapidity, affordability, and ease of use, enabling healthcare practitioners to perform reliable analyses in decentralized settings. Such diagnostic tests are usually based on bioassays that allow for the detection clinically relevant biomarkers, namely proteins, antibodies nucleic acids. In context electrochemical biosensors, implementation magnetic beads offers unique advantages stemming...
The measurement of the analyte concentration in electrochemical biosensors traditionally requires costly laboratory equipment to obtain accurate results. Innovative portable solutions have recently been proposed, but usually, they lean on personal computers (PCs) or smartphones for data elaboration and exhibit poor resolution portability proprietary software. This paper presents a low-cost system, assembling an ad hoc-designed analog front end (AFE) development board equipped with system...
Aptamers are recognition elements increasingly used for the development of biosensing strategies, especially in detection proteins or small molecule targets. Lysozyme, which is recognized as an important biomarker various diseases and a major allergenic protein found egg whites, one main analytical targets aptamer-based biosensors. However, since strategies can be prone to artifacts data misinterpretation, rigorous multifaceted characterization aptamer–target interaction needed. In this...
Vitamin C, an antioxidant in most fruits and vegetables, is highly sensitive to heat, pH, metals, light, oxidation, making it a key marker for nutrient degradation thermal processing. Research aimed at improving processing methods maximize vitamin C retention usually limited expensive laboratory equipment, which does not reflect real-world conditions the food industry. On other hand, traditional are suitable on-line monitoring. This paper proposes bridging gap liquid with voltammetric sensor...
The thioamido function of [CuCl2(1H)]Cl (2) (1 = 4-amino-1,4-dihydro-3-(2-pyridyl)-5-thioxo-1,2,4-triazole), a cytotoxic copper complex, was converted into thioether moieties, leading to the synthesis [CuCl2(3)]2 (4) and [CuCl2(5)] (6) (3 6-methyl-3-pyridin-2-yl-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine; 5 4-amino-5-ethylthio-3-(2-pyridyl)-1,2,4-triazole). These complexes were structurally characterized, their stability constants, along with biological activity, determined. 4 6 slightly...
A series of polymerizable tetraalkylammonium ionic liquids based on [2-(methacryloyloxy)ethyl]dimethylheptyl ammonium cation and bis(trifluoromethylsulfonyl)imide, nonafluoro-1-butanesulfonate, dodecylbenzenesulfonate, heptadecafluorooctanesulfonate, 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoroundecanoate anions, as well their corresponding homo- copolymers, have been synthesized characterized by means 1H NMR, TG-DTA, DSC, MALDI-TOF, viscosimetry XPS investigations. Hydrophobic CO2...
A low-cost strategy for the simple and rapid detection of bacterial cells in biological matrixes is presented herein. Escherichia coli Salmonella typhimurium were chosen as model bacteria development an electrochemical assay based on hollow AuAg nanoshells (NSs). By taking advantage their electrocatalytic properties situ generation signal without need any other kind reagent, substrate, or redox enzyme, high sensitivities (down to 102 CFU/mL) achieved. Moreover, recognition discrimination...
Nowadays, analytical techniques are moving towards the development of smart biosensing strategies for point-of-care accurate screening disease biomarkers, such as human epididymis protein 4 (HE4), a recently discovered serum marker early ovarian cancer diagnosis. In this context, present work represents first implementation competitive enzyme-labelled magneto-immunoassay exploiting homemade IoT Wi-Fi cloud-based portable potentiostat differential pulse voltammetry readout. The...
Recent advances in Internet-of-Things technology have opened the doors to new scenarios for biosensor applications. Flexibility, portability, and remote control access are of utmost importance move these devices people's homes or a Point-of-Care context rapidly share results with users their physicians. In this paper, an innovative portable device both quantitative semi-quantitative electrochemical analysis is presented. This can operate autonomously without need relying on other (e.g., PC,...
An IoT-WiFi smart and portable electrochemical immunosensor for the quantification of SARS-CoV-2 spike protein was developed with integrated machine learning features. The immunoenzymatic sensor is based on immobilization monoclonal antibodies directed at S1 subunit Screen-Printed Electrodes functionalized gold nanoparticles. analytical protocol involves a single-step sample incubation. Immunosensor performance validated in viral transfer medium which commonly used desorption nasopharyngeal...