Osteochondral transfer procedures are increasingly used to resurface full-thickness articular cartilage defects. There has not been long-term assessment/description of autogenous donor and recipient sites.The healing process occurs at the donor/host bone interfaces.Histologic, biochemical, biomechanical changes were assessed 6 months after an osteochondral in a goat model.Eight adult goats studied. In goats, 2 plugs transferred from femoral trochlea defects weightbearing portion medial...

Patients with pyarthrosiso of the knee can be effectively managed by several different methods. A retrospective review patients diagnosis septic arthritis was undertaken to determine efficacy two treatment programs. Multiple-needle arthrocentesis contrasted formal arthrotomy drainage. In this series, a longer than three-day history pyarthrosis and those Staphylococcus aureus or enteric gram-negative organisms on culture benefited from open drainage procedures in lieu repeated aspiration techniques.

The effects of freezing localized areas rabbit articular cartilage in vivo were studied at two to twelve months morphologically (gross and microscopic examination, including scanning electron microscopy), histochemically (toluidine blue safranin O), metabolically (35S uptake). Up six the frozen was intact but appeared be dead, as shown by absence stainable chondrocytes, severely decreased acid mucopolysaccharide content, significant uptake 35S. At fibrillation softening evident, clusters new...

The clinical and radiographic findings associated with the presence of hemivertebra ("wedge-shaped"vertebra) in small brachycephalic breeds dogs are reported together results post mortem examination availabel cases. condition is characterised clinically by progressive hind-leg weakness, spinal pain, abnormalities nervous system evidence muscle atrophy or other conformation. Confirmation diagnosis radiography. It suggested that congenital origin. Breed incidences reported. occurrence disorder...

Chronic rotator cuff (RC) tears affect a large portion of the population and result in substantial upper extremity impairment, shoulder weakness, pain, limited range motion. Regardless surgical or conservative treatment, persistent atrophic muscle changes limit functional restoration may contribute to failure. We hypothesized that deficits skeletal progenitor (SMP) cell pool could poor recovery following tendon repair. Biopsies were obtained from patients undergoing arthroscopic RC surgery....

Rotator cuff pathology is a common source of shoulder pain with variable etiology and pathoanatomical characteristics. Pathological processes fatty infiltration, muscle atrophy, fibrosis have all been invoked as causes for poor outcomes after rotator tear repair. The aims this study were to measure the expression key genes associated adipogenesis, myogenesis, in human injury compare among groups patients varied severities pathology.Biopsies supraspinatus obtained arthroscopically from...

The purpose of this study was to evaluate the clinical outcome patients treated with limited immobilization and early motion after repair acute Achilles tendon ruptures. Thirteen consecutive complete ruptures were identified, repaired, rehabilitated starting an average 10 days surgery. Active range begun at 23 weightbearing in a walking boot started 3.5 weeks length follow-up 27 months. Twelve 13 returned running activities 3 All 12 who participated lateral before their injury similar 7...

Background: Both microfracture and osteochondral autografting procedures have been useful in treating lesions. Hypothesis: Combining can extend the size of lesions that be treated with either technique. Study Design: Descriptive laboratory study. Methods: Eight adult goats underwent autograft transfer a 4.5-mm femoral trochlea plug into an 8-mm full-thickness chondral defect. Microfracture was performed gap region surrounding autograft. The animals were allowed normal activity until end...

The role of fresh allogeneic osteochondral allograft transplantation (OCA) in the cartilage repair algorithm has been long debated and this procedure is primarily considered as a salvage procedure, to be used when other, simple, techniques have failed. Gracitelli et al. retrospective comparison patients who received OCA primary treatment or demonstrates that outcome minimally influenced by previous failed represents an effective solution for both revision surgery chondral lesions knee. In...

The supraspinatus is most frequently involved in rotator cuff tears, a common orthopaedic condition. However, the architecture of this muscle has been described only for superficial, anterior, and posterior regions.

This report describes two cases of late cartilage delamination in young adults after different autologous cell-based techniques for restoration: 1. Matrix-assisted chondrocyte implantation (MACI) and 2. Hyaluronic acid-bone marrow aspirate concentrate (HA-BMAC). Both demonstrate that even patients who do not present with any ongoing symptoms primary surgery, a cellular-based graft's subsequent can occur later. It is possible regardless the technique used or time passed since graft failure...

The rabbit supraspinatus is a useful translational model for rotator cuff (RC) repair because it recapitulates muscle atrophy and fat accumulation observed in humans after chronic tear (the "first hit"). However, timeline of RC tissue response repair, especially with regard to recent evidence degeneration lack regeneration, currently unavailable. Thus, the purpose this study was characterize progression changes over time model. Two rounds experiments were conducted 2017-2018 2019-2020 N = 18...

The goal of this study was to evaluate, histologically and biochemically, repair the articular cartilage in a rabbit joint after use holmium:yttrium-alumi num-garnet laser chondroplasty model. In 30 New Zealand White rabbits, per formed with at an intensity 0.8 J rate 10 Hz. animals were sacrificed 12 weeks surgery. Histologically, safranin O staining index proteoglycan correlated well biochemical re sults, illustrating decrease repaired chondroplasty. damaged sur face application extensive....

Detrimental changes in the composition and function of rotator cuff (RC) muscles are hallmarks RC disease progression. Previous studies have demonstrated both atrophic degenerative muscle loss advanced disease. However, relationship between gene expression pathology remains poorly defined, large part due to a lack correlating tissue composition. Therefore, purpose this study was determine how relates biopsies from patients undergoing reverse shoulder arthroplasty (RSA). Gene related...

Twelve of 215 patients with an anterior cruciate ligament reconstruction developed a "thunk," low-pitched sound, on active extension the operative knee at average 5 months after surgery. In 4 thunk resolved without surgical treatment onset (range, 2 to 6). 3 increase in laxity was associated resolution thunk. Seven were treated arthroscopic examination. Six had graft impingement lateral wall or roof notch extension. The eliminated adequate notchplasty that corrected impingement. other...

A long-term in vivo study was performed to assess biochemical changes after laser repair of articular cartilage. Forty New Zealand White rabbits were sacrificed 26 weeks undergoing an cartilage chondroplasty with use a holmium:yttrium-aluminum-garnet at 0.8 joules per pulse and rate 10 Hz. Glycosaminoglycan content the repaired tissue decreased significantly both perpendicular (19.59 ± 5.6 μg hexosamin/mg dry tissue) tangential delivery (14.78 4.5 μg/mg) compared sham-treated (39.6 5.0...