A5004443034- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- Respiratory Support and Mechanisms
- Neonatal Respiratory Health Research
- Plant nutrient uptake and metabolism
- Ovarian function and disorders
- Plant Gene Expression Analysis
- Plant Reproductive Biology
- Cancer, Lipids, and Metabolism
- Polysaccharides and Plant Cell Walls
- Lipid metabolism and disorders
- Bone and Dental Protein Studies
- Genetic Neurodegenerative Diseases
- Genetic Associations and Epidemiology
- Cytokine Signaling Pathways and Interactions
- Periodontal Regeneration and Treatments
- Liver Diseases and Immunity
- Plant biochemistry and biosynthesis
- Asthma and respiratory diseases
- Traditional Chinese Medicine Analysis
- Epigenetics and DNA Methylation
- Mesenchymal stem cell research
- Liver Disease Diagnosis and Treatment
- Computational Drug Discovery Methods
- Endometriosis Research and Treatment
Yueyang Hospital
2025
Shanghai University of Traditional Chinese Medicine
2025
Ningxia Medical University
2022-2023
Ningxia Medical University General Hospital
2022-2023
Chinese Academy of Sciences
2014-2022
Institute of Botany
2014-2022
Beijing University of Agriculture
2022
Center for Excellence in Molecular Plant Sciences
2018-2022
State Key Laboratory of Oncogene and Related Genes
2020-2021
First Affiliated Hospital of Henan University
2021
Abiotic stresses adversely affect plant growth and the yield of crops worldwide. R2R3-MYB transcriptional factors have been found to be vital for plants confer stress response. In Arabidopsis, FOUR LIPS (FLP, MYB124) its paralogous MYB88 function redundantly regulated symmetric division guard mother cells (GMCs) abiotic Here, OsFLP was identified as an activator localized in nucleus. transiently induced by drought, salt abscisic acid (ABA). Overexpression showed enhanced tolerance drought...
The Arabidopsis stoma is a specialized epidermal valve made up of pair guard cells around pore whose aperture controls gas exchange between the shoot and atmosphere. Guard (GCs) are produced by symmetric division mother (GMCs). R2R3-MYB transcription factor FOUR LIPS (FLP) its paralogue MYB88 restrict GMC to one. Previously, upstream regions several core cell cycle genes were identified as direct targets FLP/MYB88, including B-type cyclin-dependent kinase CDKB1;1 A2-type cyclin CYCA2;3. Here...
Introduction Papillary thyroid carcinoma (PTC) generally has a favorable prognosis, yet advanced PTC higher recurrence and mortality risks. This study constructs validates competing risk model for cause-specific (CSM) in PTC. Methods Stage III-IV cases (AJCC 7th edition) from the SEER database (2010-2015) were analyzed. Patients split into training validation sets (7:3). Univariate multivariate analyses identified independent CSM predictors, forming basis of prediction nomogram. Model...
In rice, and other major cereal grass crops, stomata are arranged in linear files parallel to the long growth axis of leaves. Each stomatal unit comprises two dumbbell-shaped guard cells flanked by subsidiary cells. These morphological developmental characteristics enable respond environmental changes more efficiently. Cyclin-dependent kinases (CDKs) their cyclin partners co-ordinate cell proliferation differentiation during development multicellular organisms. contrast animals, plants have...
Abstract In order to determine the role of single nucleotide variants (SNVs) in modulating antidepressant response, we conducted a study, consisting 929 major depressive disorder (MDD) patients, who were treated with drugs (drug-only) or combination repetitive transcranial magnetic stimulation (plus-rTMS), followed by targeted exome sequencing analysis. We found that “plus-rTMS” patients presented more effective response treatment when compared ‘drug-only’ group. Our data firstly...
Objective: The purpose of this study was to explore the relationship between hemoglobin levels and metabolic disorders in patients with PCOS. Methods: A total 573 were selected, based on level; 342 PCOS divided into two groups as follows: Group (normal Hb group, n = 269) B (high 73); 231 non-PCOS C 199), D 32). general information, glucose lipid metabolism indicators, uric acid all compiled for data analysis. Results: (1) Hb, HGB concentration mean red blood cells RDW higher than those...
This study aimed to analyze tumor necrosis factor alpha (TNF-α) level in the uterine fluid of patients with polycystic ovary syndrome (PCOS) and its correlation clinical parameters PCOS.A total 162 treated Reproductive Medicine Center General Hospital Ningxia Medical University between December 2019 November 2021 were enrolled as research subjects, including 80 PCOS 82 other gynecological disease, who used controls. The patients' general data, along blood glucose, lipid, insulin, sex hormone...
Genetic locus were identified associated with acute respiratory distress syndrome (ARDS). Our goal was to explore the associations between genetic variants and ARDS outcome, as well subphenotypes.This a single-center, prospective observational trial enrolling adult patients. After baseline data collected, blood samples drawn perform whole exome sequencing, single nucleotide polymorphism (SNP)/insertion-deletion quantitative functional ICU clinical subphenotypes. Then lung injury burden...
Our aim was to detect the effects of DNA methylations in phosphoethanolamine/ phosphocholine phosphatase (PHOSPHO1) gene on therapeutic efficacy simvastatin.We used an extreme sampling approach by selecting 211 individuals from approximately top and bottom 15% adjusted lipid-lowering response residuals simvastatin (n=104 for high group n=107 low group) a total 734 subjects with hyperlipidemia. They received daily oral dose 20 mg eight consecutive weeks. methylation loci at PHOSPHO1 were...
To study the molecular mechanism of Mahuang Lianqiao Chixiaodou Decoction in treatment eczema by means network pharmacology and docking. First, TCMSP database was used to excavate active ingredient each drug predict its target, Uniprot standardize names target proteins, order obtain disease targets through GeneCards, OMIM, PharmGkb, DrugBank other databases. And next, potential on which work together were selected make a Venn diagram, Cytoscape 3.6.1 software screen out construct...
Abstract Background Genetic locus were identified associated with ARDS outcome. Our goal was to explore the associations between genetic variants and outcome of ARDS, prognostic values nucleotide polymorphism in ARDS. Methods This a single-center, prospective trial enrolling adult patients. After baseline data collected, blood samples drawn perform whole exome sequencing, single (SNP) / insertion-deletion quantitative functional ICU Then lung injury burden (LIB), which defined as ratio...
Abstract The Arabidopsis FOUR LIPS (AtFLP), an R2R3 MYB transcription factor, acts as important stomatal development regulator. Only one orthologue protein of AtFLP, Oryza sativa FLP (OsFLP), was identified in rice. However, the function OsFLP is largely unknown. In this study, we conducted RNA-seq and ChIP-seq to investigate potential role Our results reveal that probably a multiple functional regulator involved many biological processes growth stress responses mainly focus on salt...