A5086904724- Orthopedic Infections and Treatments
- Surgical site infection prevention
- Bacterial Identification and Susceptibility Testing
- Orthopaedic implants and arthroplasty
- Urinary Tract Infections Management
- Total Knee Arthroplasty Outcomes
- Antibiotic Use and Resistance
- Surgical Sutures and Adhesives
- COVID-19 and healthcare impacts
- Sepsis Diagnosis and Treatment
- Infective Endocarditis Diagnosis and Management
- Medical Device Sterilization and Disinfection
- Nosocomial Infections in ICU
- Antimicrobial Resistance in Staphylococcus
- Cardiac, Anesthesia and Surgical Outcomes
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Clostridium difficile and Clostridium perfringens research
- Patient Satisfaction in Healthcare
- Ocular Infections and Treatments
- Diphtheria, Corynebacterium, and Tetanus
- Infection Control and Ventilation
- Clinical Reasoning and Diagnostic Skills
- Colorectal Cancer Surgical Treatments
- Streptococcal Infections and Treatments
Duke University
2016-2025
Duke Medical Center
2015-2025
Duke University Hospital
2018-2025
Oregon Medical Research Center
2023-2024
University of Pittsburgh
2024
Communities In Schools of Orange County
2023-2024
New York Proton Center
2023-2024
Lindsay Unified School District
2023-2024
Manhattan Institute for Policy Research
2023
Museum of Heilongjiang Province
2021
Throughout the COVID-19 pandemic, health care personnel (HCP) have been at high risk for exposure to SARS-CoV-2, virus that causes COVID-19, through patient interactions and community (1). The Advisory Committee on Immunization Practices recommended prioritization of HCP vaccination maintain provision critical services reduce spread infection in settings (2). Early distribution two mRNA vaccines (Pfizer-BioNTech Moderna) allowed assessment effectiveness these a real-world setting. A...
ABSTRACT Pediatric patients undergoing cardiothoracic surgery are at increased risk for health care–associated infections, especially surgical site infections (SSIs). Delayed sternal closures associated with prolonged lengths of stay and contribute to infection risks morbidities. At a single‐site academic pediatric center, we created an SSI‐prevention bundle targeting the preoperative, intraoperative, postoperative care periods. Using standard criteria, determined epidemiology SSIs measured...
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Abstract The optimal treatment of prosthetic joint infection (PJI) remains uncertain. Patients undergoing debridement, antibiotics, and implant retention (DAIR) receive extended antimicrobial treatment, some experts leave patients at perceived highest risk relapse on suppressive antibiotic therapy (SAT). In this narrative review, we synthesize the literature concerning role SAT to prevent failure following DAIR, attempting answer 3 key questions: (1) What factors identify for after DAIR (ie,...
Pre-exposure prophylaxis (PrEP) is an effective HIV prevention method, but many primary care physicians (PCPs) have not incorporated PrEP into practice. While may be a key strategy to reducing high transmission rates in the southern US, knowledge about prescribing patterns among PCPs this region lacking. An online survey was sent large network of at academic medical center North Carolina October 2015. The repeated September 2016, after educational intervention that included on-site trainings...
Overusing blood cultures (BCxs) can lead to false positives, unnecessary antibiotics, and increased healthcare costs. Despite studies on inpatient BCx algorithms, none have focused cardiothoracic surgery (CTS) patients, with complex postoperative care invasive devices. This study aimed evaluate the impact of a algorithm event (BCE) rates in CTS step-down units. The was conducted 3 units at Duke University Hospital. algorithm, based Seidelman et al. (2023), implemented June 2023. BCE rates,...
Background Rifampin therapy is indicated for the treatment of staphylococcal periprosthetic joint infection (PJI) in patients who have undergone debridement, antibiotics, and implant retention (DAIR) or one-stage revision as per Infectious Diseases Society America (IDSA) guideline. Given well-established effectiveness rifampin adjunctive PJI, it crucial to evaluate its utilization practice identify factors that contribute underuse incomplete administration, these deviations may undermine...
Abstract This study evaluates the implementation of a blood culture (BCx) algorithm in neurology ICU (NICU) to reduce BCx event (BCE) rates. Results show reduction BCE rates, without increasing adverse outcomes. The findings support feasibility algorithms for improving diagnostic stewardship specialized NICU population.
Abstract Background Blood culture (BCx) diagnostic stewardship aids in accurately identifying microbial pathogens and guiding appropriate antibiotic therapy. We compared effects of a BCx algorithm (Fig 1) on rates (BCx/100 ED visits) the emergency department (ED) using two implementation approaches: an intensive approach including weekly, individualized appropriateness data feedback modifications to electronic health record order sets, 2) passive with group-level, random sample.Figure 1:ED...
Abstract Background Diagnostic stewardship of blood culture utilization is paramount to mitigate the risks associated with excessive culturing, including increased contamination rates and inappropriate antimicrobial administration. Although algorithms have been studied previously, there insufficient data on their application specifically in solid organ transplant recipients. This study aims retrospectively apply a algorithm (initially developed for non-immunocompromised population) assess...
Abstract Background Different societies and organizations use different surgical site infection (SSI) definitions for surveillance. With multiple in use, validation of surveillance findings becomes paramount, particularly maintaining surgeon buy-in during data review developing countermeasures. The goal our study was to assess concordance between SSI diagnoses following peripheral vascular bypass (PVBY) surgery derived from by a (vascular) those identified through performed the prevention...
Abstract Background Surgical site infections (SSI) complicate 4.8-12.4% of orthotopic heart transplants (OHT) and result in increased length hospital stay, mortality, health care costs. As such, the need for accurate SSI surveillance systems OHT is critical. This study aimed to evaluate diagnostic accuracy National Healthcare Safety Network (NHSN) Society Thoracic Surgeons (STS) against gold standard a detailed manual adjudication process performed by Transplant ID physicians (TXID). Methods...
Abstract Background The rising incidence of total joint arthroplasties being performed is leading to an increased number prosthetic infections (PJI). PJI treatment complex, thus a collaborative approach involving orthopaedic surgeons and infectious disease (ID) providers growing. This single institution has weekly combined Ortho-ID (OID) clinic that sees patients staffed by replacement fellows ID attendings. project sought survey the fellow participants from recent years regarding impact...
Abstract Serious superficial incisional surgical site infections (SSISSIs) are a critical subset of SSIs that require intervention or lead to hospital readmission. Analyzing 11,617 from 47 community hospitals, the inclusion SSISSIs changed 30/47 rankings (p = 0.02), highlighting need for in standardized infection surveillance models.
Abstract Objective: Sparse recent data are available on the epidemiology of surgical site infections (SSIs) in community hospitals. Our objective was to provide updated complex SSIs hospitals and characterize trends SSI prevalence rates over time. Design: Retrospective cohort study. Methods: were collected from patients undergoing 26 commonly performed procedures at 32 southeastern United States 2013 2018. calculated for each year stratified by procedure causative pathogen. Results: Over...