A5101758357- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Nerve injury and regeneration
- Long-Term Effects of COVID-19
- Antimicrobial Resistance in Staphylococcus
- Antifungal resistance and susceptibility
- Venous Thromboembolism Diagnosis and Management
- Liver Disease and Transplantation
- COVID-19 and healthcare impacts
- Organ Transplantation Techniques and Outcomes
- Influenza Virus Research Studies
- Oxidative Organic Chemistry Reactions
- Vaccine Coverage and Hesitancy
- Axial and Atropisomeric Chirality Synthesis
- Transplantation: Methods and Outcomes
- Respiratory viral infections research
- Central Venous Catheters and Hemodialysis
- Microscopic Colitis
- Clinical Reasoning and Diagnostic Skills
- Hallucinations in medical conditions
- Actinomycetales infections and treatment
- Medical Education and Admissions
- Infection Control and Ventilation
- Hereditary Neurological Disorders
- Disaster Response and Management
National Heart Lung and Blood Institute
2023
Ronald Reagan UCLA Medical Center
2022
UNSW Sydney
2022
Sydney Hospital
2022
Prince of Wales Hospital
2022
Macquarie University
2022
Royal Prince Alfred Hospital
2022
Princess Alexandra Hospital
2022
The University of Queensland
2022
Sydney Adventist Hospital
2022
Objectives: To determine the association between vision and hearing impairment subsequent cognitive functional decline in community‐residing older women. Design: Prospective cohort study. Setting: Four metropolitan areas of United States. Participants: A total 6,112 women aged 69 participating Study Osteoporotic Fractures (SOF) 1992 1994. Measurements: Five thousand three hundred forty‐five participants had measured, 1,668 visual acuity 1,636 both measured. Visual was defined as corrected...
Throughout the COVID-19 pandemic, health care personnel (HCP) have been at high risk for exposure to SARS-CoV-2, virus that causes COVID-19, through patient interactions and community (1). The Advisory Committee on Immunization Practices recommended prioritization of HCP vaccination maintain provision critical services reduce spread infection in settings (2). Early distribution two mRNA vaccines (Pfizer-BioNTech Moderna) allowed assessment effectiveness these a real-world setting. A...
BackgroundThe prioritization of U.S. health care personnel for early receipt messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes disease 2019 (Covid-19), allowed evaluation effectiveness these new in a real-world setting.MethodsWe conducted test-negative case–control study involving across 25 states. Cases were defined on basis positive polymerase-chain-reaction (PCR) or antigen-based test SARS-CoV-2 and at least one...
The enantioselective synthesis of flavanones and chromanones is described. Bifunctional thiourea catalysts promote an asymmetric oxo-conjugate addition to a β-ketoester alkylidene in high yields with excellent enantioselectivity (80−94% ee) for aryl alkyl substrates. Decarboxylation the proceeds smoothly one-pot procedure afford enantioenriched chromanones.
The incidence of infections caused by Candida glabrata and krusei, which are generally more resistant to fluconazole than albicans, is increasing in hospitalized patients. However, the extent prior exposure specific antimicrobial agents increases risk subsequent C. or krusei candidemia has not been closely studied. A retrospective case-case-control study was performed at a university hospital. From 1998 2003, 60 patients were identified with hospital-acquired non-C. albicans (C. krusei; case...
To determine the rate of postinjection endophthalmitis and compare microbial etiology outcomes in office-based injection-related versus those acquired after operating room procedures.Retrospective, observational case series. Consecutive cases seen at Retina Consultants Houston between July 2000 2010 were classified as postsurgical or post-intravitreal injection. Cases secondary to glaucoma surgery, trauma, endogenous sources excluded. Main study measures incidence endophthalmitis,...
Objective Traumatic peripheral nerve injuries often produce permanent functional deficits despite optimal surgical and medical management. One reason for the impaired target organ reinnervation is degradation of motor endplates during prolonged denervation. Here we investigate effect preserving agrin on stability denervated endplates. Because matrix metalloproteinase 3 (MMP3) known to degrade agrin, examined changes in endplate structure following traumatic injury MMP3 knockout mice. Methods...
OBJECTIVES: To compare treatment and outcomes for older persons with stroke in Medicare health maintenance organizations (HMOs) fee‐for‐service (FFS) systems. DESIGN: Inception cohort stratified by payer followed 1 year. SETTING: Six HMOs five FFS systems large populations the West, Midwest, Eastern United States. PARTICIPANTS: A total of 429 randomly selected patients receiving rehabilitation nursing homes or hospitals (RHs) from June 1993 to 1995. MEASUREMENTS: Improvement activities daily...
Chronic nerve compression (CNC) injuries occur when peripheral nerves are subjected to sustained mechanical forces, with increasing evidence implicating Schwann cells as key mediators. Integrins, a family of transmembrane adhesion molecules that capable intracellular signaling, have been implicated in variety biological processes such myelination and regeneration. In this study, we seek define the physical stimuli mediating demyelination determine whether integrin plays role demyelinating...
This report describes the creation of a venocutaneous fistula to salvage free fibular osteocutaneous flap compromised by extensive venous thrombosis. technique has previously been described for digital replants, but this is first being used flap. A 21-year-old woman underwent 9-cm resection distal left tibia an aneurysmal bone cyst. contralateral right was reconstruction. On postoperative day 2, skin paddle showed evidence congestion. Reexploration demonstrated thrombosis throughout entire...
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OBJECTIVE To determine the impact of recurrent Clostridium difficile infection (RCDI) on patient behaviors following illness. METHODS Using a computer algorithm, we searched electronic medical records 7 Chicago-area hospitals to identify patients with RCDI (2 episodes CDI within 15 56 days each other). was validated by record review. Patients were asked complete telephone survey. The survey included questions regarding general health, social isolation, symptom severity, emotional distress,...
Our recent experiments demonstrate that demyelination enhances peripheral nerve regeneration after contusion injury in the adult rat sciatic nerve. The role of a transection model has yet to be elucidated. We hypothesize (1) axon within region increases experimental, immunologic demyelination, and (2) regenerated axons are partially derived from proximal motor axons.Sciatic nerves female Sprague-Dawley rats (n = 20) were injected with demyelinating agent immediately injury. harvested 1 month...
Transesophageal echocardiography can be useful not only in diagnosing venous air embolism but also guiding aspiration of from the pulmonary artery. A 59-year-old man with a history cirrhosis underwent combined kidney and liver transplantations. He developed acute hypotension after native was removed due to massive via retained transjugular intrahepatic portosystemic shunt catheter. revealed artery resulting outflow obstruction. Under echocardiographic guidance, arterial catheter withdrawn...
Biliary complication is the Achilles' heel for live donor liver transplant. Bile leak particularly difficult to manage as anastomotic site was often angled acutely. We described a patient with bile managed by modified rendezvous technique whereby endoscopist and radiologist work simultaneously under fluoroscopy. Unlike traditionally where grasping of guidewire occurred at duodenum, biloma in this technique. Insertion biliary stent could then be performed over through duodenoscope. The...