A5082586023- Streptococcal Infections and Treatments
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Urinary Tract Infections Management
- Appendicitis Diagnosis and Management
- Intraperitoneal and Appendiceal Malignancies
- Pneumonia and Respiratory Infections
- Rabies epidemiology and control
- Emergency and Acute Care Studies
- Pediatric Urology and Nephrology Studies
- Sepsis Diagnosis and Treatment
- Nosocomial Infections in ICU
- Viral Infections and Vectors
- Urinary Bladder and Prostate Research
- Clostridium difficile and Clostridium perfringens research
- Respiratory viral infections research
- Viral Infections and Outbreaks Research
- Intestinal Malrotation and Obstruction Disorders
- Antibiotic Resistance in Bacteria
- Antibiotics Pharmacokinetics and Efficacy
- COVID-19 and healthcare impacts
- Viral gastroenteritis research and epidemiology
- Antibiotic Use and Resistance
- Bacillus and Francisella bacterial research
- SARS-CoV-2 and COVID-19 Research
University of California, Los Angeles
2016-2025
University of Iowa
2020-2025
Education and Research Institute
2020-2025
UCLA Health
2015-2025
Olive View-UCLA Medical Center
2014-2024
Ronald Reagan UCLA Medical Center
2015-2024
Los Angeles Medical Center
2006-2024
AID Atlanta
2024
University of Michigan
2009-2023
Swedish Medical Center
2021
Evidence-based guidelines for the management of patients with methicillin-resistant Staphylococcus aureus (MRSA) infections were prepared by an Expert Panel Infectious Diseases Society America (IDSA). The are intended use health care providers who adult and pediatric MRSA infections. discuss a variety clinical syndromes associated disease, including skin soft tissue (SSTI), bacteremia endocarditis, pneumonia, bone joint infections, central nervous system (CNS) Recommendations provided...
Methicillin-resistant Staphylococcus aureus (MRSA) is increasingly recognized in infections among persons the community without established risk factors for MRSA.We enrolled adult patients with acute, purulent skin and soft-tissue presenting to 11 university-affiliated emergency departments during month of August 2004. Cultures were obtained, clinical information was collected. Available S. isolates characterized by antimicrobial-susceptibility testing, pulsed-field gel electrophoresis,...
Evidence-based guidelines for the management of patients with methicillin-resistant Staphylococcus aureus (MRSA) infections were prepared by an Expert Panel Infectious Diseases Society America (IDSA). The are intended use health care providers who adult and pediatric MRSA infections. discuss a variety clinical syndromes associated disease, including skin soft tissue (SSTI), bacteremia endocarditis, pneumonia, bone joint infections, central nervous system (CNS) Recommendations provided...
To define better the bacteria responsible for infections of dog and cat bites, we conducted a prospective study at 18 emergency departments. be eligible enrollment, patients had to meet one three major criteria infection bite wound (fever, abscess, lymphangitis) or four five minor (wound-associated erythema, tenderness site, swelling purulent drainage, leukocytosis). Wound specimens were cultured aerobic anaerobic research microbiology laboratory and, in some cases, local hospital laboratories.
UNITED STATES AT LEAST 250 000 episodes of acute pyelonephritis occur annually among adult women, resulting in as many 100 hospitalizations. 1,2However, the optimal antimicrobial regimen and duration therapy for this infection have not been established.4][5] Three-day regimens trimethoprim-sulfamethoxazole or fluoroquinolones appear to provide adequate cure rates, while being associated with lower cost fewer adverse effects than longer regimens.The current standard uncomplicated is 14 days,...
Background. In the past decade, new methicillin-resistant Staphylococcus aureus (MRSA) strains have emerged as a predominant cause of community-associated skin and soft-tissue infections (SSTIs). Little information exists regarding trends in MRSA prevalence molecular characteristics or antimicrobial susceptibility profiles S. isolates. Methods. We enrolled adults with acute, purulent SSTIs presenting to US network 12 emergency departments during August 2008. Cultures clinical were collected....
U.S. emergency department visits for cutaneous abscess have increased with the emergence of methicillin-resistant Staphylococcus aureus (MRSA). The role antibiotics patients a drained is unclear.
Throughout the COVID-19 pandemic, health care personnel (HCP) have been at high risk for exposure to SARS-CoV-2, virus that causes COVID-19, through patient interactions and community (1). The Advisory Committee on Immunization Practices recommended prioritization of HCP vaccination maintain provision critical services reduce spread infection in settings (2). Early distribution two mRNA vaccines (Pfizer-BioNTech Moderna) allowed assessment effectiveness these a real-world setting. A...
BackgroundThe prioritization of U.S. health care personnel for early receipt messenger RNA (mRNA) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes disease 2019 (Covid-19), allowed evaluation effectiveness these new in a real-world setting.MethodsWe conducted test-negative case–control study involving across 25 states. Cases were defined on basis positive polymerase-chain-reaction (PCR) or antigen-based test SARS-CoV-2 and at least one...
Community-associated methicillin-resistant Staphylococcus aureus (MRSA) is the most common pathogen among patients with skin and soft tissue infections seeking treatment at a Los Angeles (USA) area emergency department. The proportion caused by MRSA increased from 29% in 2001 to 2002 64% 2003 2004. No clinical or historical features reliably predict etiology.
By using optimum sampling, transport, and culture techniques in patients with gangrenous or perforated appendicitis, we recovered larger numbers of bacteria a more diverse flora than has previously been reported. Thirty older 12 years histologically documented appendicitis had peritoneal fluid, appendiceal tissue, abscess contents (if present) cultured. Appendiceal tissue was obtained so as to exclude the lumen. A total, 223 anaerobes 82 aerobic faculatative were recovered, an average 10.2...
Previous studies of infected human bites have been limited by small numbers patients and suboptimal microbiologic methodology. We conducted a multicenter prospective study 50 with bites. Seventy percent the assailants were young adult men. Fifty-six injuries clenched-fist 44% occlusional Most to hands. Fifty-four hospitalized. The median number isolates per wound culture was 4 (3 aerobes 1 anaerobe); anaerobes isolated from 54% wounds, alone 44%, 2%. Isolates included Streptococcus anginosus...
Clostridium difficile infection is the most common health-care-associated in USA. We assessed safety and efficacy of ridinilazole versus vancomycin for treatment C infection.We did a phase 2, randomised, double-blind, active-controlled, non-inferiority study. Participants with signs symptoms positive diagnostic test result were recruited from 33 centres USA Canada randomly assigned (1:1) to receive oral (200 mg every 12 h) or (125 6 10 days. The primary endpoint was achievement sustained...
For 2013-2014, we prospectively identified US adults with flank pain, temperature >38.0°C, and a diagnosis of acute pyelonephritis, confirmed by culture. Cultures from 453 (86.9%) 521 patients grew Escherichia coli. Among E. coli isolates 272 uncomplicated pyelonephritis 181 complicated prevalence fluoroquinolone resistance across study sites was 6.3% (range site 0.0%-23.1%) 19.9% (0.0%-50.0%), respectively; extended-spectrum β-lactamase (ESBL) production 2.6% (0.0%-8.3%) 12.2% (0.0%-17.2%),...