A5005100775- Temporomandibular Joint Disorders
- Obstructive Sleep Apnea Research
- Voice and Speech Disorders
- Dental Health and Care Utilization
- Neurological disorders and treatments
- Sleep and Wakefulness Research
- Advanced Sensor and Energy Harvesting Materials
- Dental Implant Techniques and Outcomes
- Dysphagia Assessment and Management
- Transcranial Magnetic Stimulation Studies
- Nanomaterials for catalytic reactions
- Dental Radiography and Imaging
- Dental Research and COVID-19
- Dental materials and restorations
- Orthodontics and Dentofacial Orthopedics
- Liver Disease Diagnosis and Treatment
- Neuroscience and Neural Engineering
- Gastrointestinal Bleeding Diagnosis and Treatment
- Pluripotent Stem Cells Research
- Disaster Response and Management
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Innovative Microfluidic and Catalytic Techniques Innovation
- Botulinum Toxin and Related Neurological Disorders
- Microbial infections and disease research
Gifu Pharmaceutical University
2023-2025
Showa University
2016-2024
Gunma University
2024
Tsukuba International University
2024
University of Tsukuba
2024
Yokohama City University
2009-2023
Japan Society for the Promotion of Science
2023
GTx (United States)
2022
In-Q-Tel
2022
University of Southern California
2020
Sleep bruxism is a sleep-related movement disorder that can be responsible for various pains and dysfunctions in the orofacial region. The aim of current case-control association study was to investigate genetic, psychological behavioral factors with sleep Japanese population. Non-related participants were recruited divided into either group (n = 66) or control 48) by clinical diagnoses 3-night masseter electromyographic recordings means portable miniature device. Epworth Sleepiness Scale,...
Even though tetrodotoxin (TTX) is a widespread toxin in marine and terrestrial organisms, very little known about the biosynthetic pathway used to produce it. By describing chemical structures of natural analogs TTX, we can start identify some precursors that might be important for TTX biosynthesis. In present study, an analog 5,11-dideoxyTTX, was identified first time sources, ovary pufferfish pharynx flatworm (planocerid sp. 1), by comparison with totally synthesized (−)-5,11-dideoxyTTX,...
Summary The aim of this study was to investigate the association between patterns jaw motor activity during sleep and clinical signs symptoms bruxism. A total 35 university students staff members participated in after providing informed consent. All participants were divided into either a bruxism group ( n = 21) or control 14), based on following diagnostic criteria: (1) reports tooth‐grinding sounds for at least two nights week preceding 6 months by their partner; (2) presence tooth...
The synthesis of polycyclic aromatic compounds generally requires stoichiometric oxidants or homogeneous metal catalysts, however, the risk contamination inorganic residues can affect their properties. Here we present a microwave (MW)-assisted platinum on beaded activated carbon (Pt/CB)-catalyzed C-C bond formation diarylacetylenes and hydrocarbons under continuous-flow conditions. Various fused were continuously synthesized via dehydrogenative C(sp2)-C(sp2) C(sp2)-C(sp3) with yields up to...
A case-controlled study was performed to investigate the association of colonic angiectasia with other conditions and identify risk factors for bleeding.Information collected from all patients who underwent colonoscopy at our hospital between January 2008 December 2010. Data on 90 individuals [58 men; median age 69 (26-92) years] were compared those 180 without angiectasia, matched gender age.Multivariate analysis showed that occult gastrointestinal bleeding [odds ratio (OR) 2.523; 95%...
Objectives: The purpose of this study was to evaluate the accuracy diagnosing vertical root fractures (VRFs) by comparing volume bone defects in VRFs with those non-VRFs on reconstructed three-dimensional (3D) models (TDMs) using CBCT. Methods: 32 maxillary pre-molars and anterior teeth radiolucent areas were evaluated pre-operative CBCT images. Of teeth, 16 had a fractured (VRF group) non-fractured (non-VRF group). area each tooth traced dimension [mesiodistal, buccolingual horizontal (the...
Fourteen chicks, 7-12 days old, that died or had neurological signs (depression, paralysis, torticollis, incoordination, and rolling) were investigated pathologically microbiologically. Variably sized foci of malacia present within the parenchyma brain stem (cerebral peduncle, optic lobe, medulla oblongata) cerebral hemisphere. Capillary thrombosis with congestion hemorrhage was frequently observed lesions. Gram-positive cocci recognized in blood capillary Bacteriologically, Enterococcus...
Pegylated interferon and ribavirin combination therapy is the standard treatment for patients with chronic hepatitis C (CHC). Some groups have reported a relation between lipid values response while others that microsomal triglyceride transfer protein, key enzyme in assembly secretion of lipoproteins, was related to virus (HCV). The aim this study investigate association lipoprotein profiles, classified according size, usefulness predicting outcome treatment. Forty-four CHC (27 men 17 women)...
Implant-supported fixed partial dentures (IFPDs) are a treatment option for partially edentulous dentition with missing posterior-most molars despite the concept of shortened dental arch (SDA). This study aimed to evaluate effect IFPD on oral health-related quality life (OHRQoL) in patients unilateral SDA two adjacent and compare effects single- two-unit IFPDs. Forty (Kennedy Class II) participated this study; 11 received one implant placement first molar were treated single-unit...
We measured section thickness (ST) after slicing using a film meter and investigated the relationship between ST percent area of positive staining computer-assisted image analysis.
Background Contingent vibratory feedback stimuli applied by a specially designed oral appliance (OA) have been reported to be effective in reducing sleep bruxism (SB). However, the inhibitory effects of OA, which occur immediately after OA delivery, may confounded this finding. Objective This study sought shed light on SB adaptation period, when its are diminished. Methods Fourteen ‘definite’ patients were enrolled. A force‐based detection system was utilised trigger vibrator attached OA....
Purpose Implant-assisted removable partial dentures (IARPDs) with short implants improve the oral functions of (RPDs). This study aimed to compare patient-reported outcomes RPDs and IARPDs retained by magnetic attachments.Methods We recruited 30 participants mandibular Kennedy Class I or II distal extension defects three more teeth. RPDs, a healing cap, attachment were evaluated across stages using outcomes. All completed questionnaires (oral health-related quality life [OHRQoL], patient...
The pathogenesis of conjunctivitis caused by Newcastle disease viruses (NDVs) was investigated in 3-week-old specific-pathogen-free chickens. chickens were inoculated intramuscularly, eye drop or intranasally, with 107 plaque forming units viscerotropic velogenic virus (VVNDV), mesogenic NDV lentogenic NDV. Macroscopically, lower palpebral conjunctivae appeared red oedematous swelling VVNDV. Histologically, mild lesions focal hyperplasia the conjunctival epithelial cells cellular...
This study investigated the diagnostic accuracy of Sleep Profiler, which relies on ambulatory polysomnography (PSG) with electroencephalogram for sleep bruxism (SB) and examined its episode-by-episode agreement in comparison to PSG equipped audiovisual recordings (avPSG).
Lymphoid neoplasms of abdominal cavity origin were found in two cows infected with bovine leukemia virus (BLV). Case 1 was a 3-year-old Japanese Black cow affected B-1 B cell lymphoma. 2 14-year-old that developed γδ T Immunohistochemically, CD79a-positive lymphoma cells observed case 1, whereas CD3-, WC1- or perforin-positive ones seen 2. Despite the expression CD5 both lymphomas, reactivity surface cytoplasmic and membrane Erythrophagia by tumor cases considered to be due fact their normal...
Various biofeedback stimulation techniques for managing sleep bruxism (SB) have recently emerged; however, the effect of successive application vibratory feedback has not been clarified. This study aimed to elucidate vibration via an oral appliance (OA) on SB. prospective, single-arm, open-label intervention included 20 participants diagnosed with "definite" SB who wore a specially designed OA 98 nights at home. A force-based detection system triggered vibrator attached OA. Vibratory was...
In cases of missing posterior teeth, treatment modalities based on the shortened dental arch (SDA) concept may be a viable alternative. However, association between oral health-related quality life (OHRQoL) and patients' decisions remains unclear. This study aimed to investigate OHRQoL decision treated with implant-supported fixed partial dentures (IFPDs) or take wait-and-see approach in patients an SDA single second molar clarify impact IFPD OHRQoL. The Oral Health Impact Profile (OHIP)...
Sleep bruxism (SB) is a sleep-related movement disorder characterized by grinding and clenching of the teeth during sleep. We previously found significant association between SB single nucleotide polymorphism (SNP), rs6313, in neuronal serotonin 2A receptor gene (HTR2A), established human induced pluripotent stem cell (iPSC)-derived neurons from patients with genetic variant. To elucidate electrophysiological characteristics iPSC-derived neural cells bearing an SB-related variant, we...
This prospective study aimed to compare the oral functions of removable partial dentures (RPDs) with those implant-assisted (IARPDs) short implants and magnetic attachments in patients mandibular Kennedy class I II.Thirty participants or II at least three distal missing teeth were recruited. Oral functions, including mixing ability, comminuting maximum bite force, occlusal contact area, assessed for RPDs (stage 0), IARPDs healing caps 1), 2). The loaded force stages 1 2. Finally, data 27 who...