A5066673414- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Moyamoya disease diagnosis and treatment
- Vascular Malformations Diagnosis and Treatment
- Comparative Animal Anatomy Studies
- Cardiovascular Health and Disease Prevention
- Congenital Heart Disease Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Palliative Care and End-of-Life Issues
- Cardiovascular Effects of Exercise
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
- Cardiac Health and Mental Health
- Inflammatory mediators and NSAID effects
- Geriatric Care and Nursing Homes
- Oropharyngeal Anatomy and Pathologies
- Antiplatelet Therapy and Cardiovascular Diseases
- Evolution and Paleontology Studies
- Cholinesterase and Neurodegenerative Diseases
- Advanced MRI Techniques and Applications
- Neurological Complications and Syndromes
- Physiological and biochemical adaptations
- Rheumatoid Arthritis Research and Therapies
- Neurological Disease Mechanisms and Treatments
Nakamura Memorial Hospital
2016-2025
The University of Tokyo
1998-2025
Iwate Prefectural Central Hospital
2014-2024
Juntendo University Shizuoka Hospital
2024
Juntendo University
2022-2023
Osaka International Cancer Institute
2018
Toho University
2013-2017
Kindai University
1996-2017
Tokyo-Kita Medical Center
2017
Kindai University Sakai Hospital
2017
<h3>Background and aims:</h3> The effect of adiponectin on colorectal carcinogenesis has been proposed but not fully investigated. We investigated the deficiency development cancer. <h3>Methods:</h3> generated three types gene-deficient mice (adiponectin-deficient, receptor 1-deficient, 2-deficient) chemical-induced colon polyp formation cell proliferation in epithelium. Western blot analysis was performed to elucidate mechanism which affected by deficiency. <h3>Results:</h3> numbers polyps...
See also: Commentaire de travail C. Katada et al., pp. 779Endoscopy 2007; 39(09): 930-930DOI: 10.1055/s-0032-1308866
<h3>Background and aims</h3> Obesity increases the risk of colorectal cancer (CRC). Serum leptin levels are markedly elevated in obese individuals, but involvement CRC growth remains unclear. We explored hypothesis that signalling regulates CRC, by examining effects deficiency on murine colon tumour growth. <h3>Methods</h3> used genetic (leptin-deficient receptor-deficient) models obesity investigated carcinogen-induced polyp formation cell proliferation colonic epithelium. Colonic tissues...
Summary Infiltration of various types leucocytes has been shown to play a crucial role in the pathogenesis rheumatoid arthritis (RA). Macrophage inflammatory protein-3α (MIP-3α) is recently identified chemokine which selective chemoattractant for such as memory T cells, naïve B cells and immature dendritic cells. In this study, we investigated expression MIP-3α its specific receptor CCR6 inflamed joints patients with RA. Increased amounts were found by ELISA synovial fluids (SF) was...
<h3>Objective:</h3> No effective drugs have been developed to date prevent or treat non-alcoholic fatty liver disease (NAFLD), although diet modification and exercise improve obesity attempted. Therefore, development of a novel drug/strategy NAFLD is urgently needed. In the present study, concept proposed for treatment NAFLD. <h3>Methods:</h3> Fisher 344 male rats were given choline-deficient, l-amino acid-defined (CDAA) high-fat high-calorie (HF/HC) with without antiplatelet agents,...
There is no established treatment for the acute exacerbation of trigeminal neuralgia. We aimed to investigate efficacy and safety intravenous fosphenytoin this disease. conducted a retrospective observational study data from 41 patients with neuralgia who received therapy. Fosphenytoin diluted physiological saline was administered intravenously at loading dose 9.8-20.7 mg/kg or 7.5-9.5 when maintenance therapy needed. Pain evaluated using numerical rating scale (NRS), assessed immediately...
Arterial dissection is a rare complication of mechanical thrombectomy, and the risk factors clinical course are not well known. We report case iatrogenic on atherosclerotic stenosis middle cerebral artery (MCA) caused by stent retriever thrombectomy for internal carotid (ICA) embolic occlusion. A 78-year-old woman underwent ICA Preprocedural angiography indicated thrombus from C1 segment left to proximal M1 MCA slow antegrade contrast opacification mid- distal-M1. was deployed across...
An association between magnetic resonance imaging detection of intraplaque hemorrhage and the risk cerebral ischemic events has been described. However, few studies have followed patients with hemorrhage.We used 3-dimensional gradient-echo black-blood T1-weighted (screening BB [S-BB]) as a sequence to evaluate acute cerebrovascular stroke. The S-BB high signal plaques subsequent ipsilateral was investigated.A total 928 consecutive hospitalized for stroke or transient attack according Trial...
Abstract The intracranial carotid rete (or mirabile epidurale) is a unique blood vascular system supplying the brain of artiodactyls, which have either an involuted or no internal artery. Although lesser and greater mouse deer ( Tragulus javanicus T. napu , respectively) are ruminants, epidurale absent. In these animals, as in non‐artiodactyls, such canines, equines humans, complete artery supplies brain. It currently uncertain whether absence confined to among ruminants. provides new...
Fenestration is a rare anatomical variation in the posterior cerebral artery. To best of our knowledge, there are few reports fenestrations at artery P1-P2 junction. Herein, we report case fenestration junction diagnosed by 3-T magnetic resonance imaging and angiography. A 75-year-old woman visited hospital because headaches. Magnetic incidentally showed around segment right angiography revealed small The vessel diameter both limbs forming was nearly equal. Careful assessment important to...