A5101751494- Fluid Dynamics and Heat Transfer
- Fluid Dynamics and Mixing
- Innovative Microfluidic and Catalytic Techniques Innovation
- Hydrocarbon exploration and reservoir analysis
- Seed Germination and Physiology
- Heat Transfer and Optimization
- Rheology and Fluid Dynamics Studies
- Plant Molecular Biology Research
- Petroleum Processing and Analysis
- Epigenetics and DNA Methylation
- Viral gastroenteritis research and epidemiology
- Analytical chemistry methods development
- Lattice Boltzmann Simulation Studies
- Surface Modification and Superhydrophobicity
- Fluid Dynamics and Thin Films
- RNA modifications and cancer
- Heat Transfer Mechanisms
- Analytical Chemistry and Chromatography
- Barrier Structure and Function Studies
- Molecular Biology Techniques and Applications
- Model Reduction and Neural Networks
- Pharmaceutical and Antibiotic Environmental Impacts
- Enhanced Oil Recovery Techniques
- Evolutionary Psychology and Human Behavior
- Connexins and lens biology
Chongqing University
2024
Institute of Genetics and Developmental Biology
2021-2024
Chinese Academy of Sciences
2021-2024
Jiangsu Academy of Agricultural Sciences
2017-2024
Nanjing University of Science and Technology
2023-2024
Second Affiliated Hospital of Zhejiang University
2018-2024
Shenyang Agricultural University
2014-2024
Liaoning Academy of Agricultural Sciences
2022-2024
State Key Laboratory of Food Science and Technology
2024
University of California, Santa Barbara
2022-2023
Necroptosis, oxidative stress, and inflammation are major contributors to the pathogenesis of ischemic acute kidney injury. Necrostatin-1 (Nec-1), an inhibitor kinase domain receptor-interacting protein kinase-1 (RIP1), has been reported regulate renal ischemia reperfusion (I/R) injury; however, its underlying mechanism action remains unclear. HK-2 cells were used create in vitro I/R model, which subjected hypoxia, followed by 2, 6, 12 h reoxygenation. For vivo study, a rat model was...
Mongolian oak (Quercus mongolica Fisch.) is an ecologically and economically important white species native to widespread in the temperate zone of East Asia. Here, we present a chromosome-scale reference genome assembly Q. mongolica, representative species, by combining Illumina PacBio data with Hi-C mapping technologies that first created for Asian oak. Our results showed draft size was 809.84 Mb, BUSCO complete gene percentage 92.71%. scaffolding anchored 774.59 Mb contigs (95.65%...
ABSTRACT The epithelial cholinergic system plays an important role in water, ion and solute transport. Previous studies have shown that activation of muscarinic acetylcholine receptors (mAChRs) regulates paracellular transport cells; however, the underlying mechanism is still largely unknown. Here, we found mAChR by carbachol cevimeline reduced transepithelial electrical resistance (TER) increased permeability tracers rat salivary SMG-C6 cells. Carbachol induced downregulation redistribution...
The influence of particles on the external jet flame generated by 18650 lithium-ion batteries during thermal runaway is considered. A model that employed multi-component Navier-Stokes equations to consider gas-phase flow, and used Lagrangian method solid particles, was applied describe mixing characteristics flames battery combustion. related combustion process, with without compared analyzed, flow lines outside were obtained. Moreover, effect concentration components elevation height are...
EZH2 is a negative prognostic factor and overexpressed or activated in most human cancers including head neck squamous cell carcinoma (HNSCC). Analysis of The Cancer Genome Atlas (TCGA) HNSCC data indicated that over-expression was associated with high tumor grade conferred poor prognosis. inhibition triggered apoptosis, cycle arrest decreased growth vitro. MICU1 (mitochondrial calcium uptake1) shown to be down regulated when expression inhibited HNSCC. When the were inhibited, cells became...
Off-label drug use is widespread in pediatric treatment, and the implementation of guidelines on this topic remains challenging. The objective study was to evaluate current practice awareness healthcare professionals towards off-label use, as well barriers guideline among Shanghai, China. A validated questionnaire issued representatives pediatricians, pharmacists, nurses administrators from hospitals with qualification Shanghai. total 679 completed questionnaires 69 were included analysis....
In this work, the rise of Taylor bubbles in a vertical tube filled with viscoelastic media is investigated by means volume-of-fluid-based direct numerical simulations. The rheological behaviors nonlinear liquids are described exponential Phan-Thien–Tanner constitutive model. applicability our simulations to capture liquid film around bubble has been validated comparisons and experimental data literature. effects fluid elasticity [indicated Weissenberg (Wi) number] gas holdup mainly discussed...
Abstract Temozolomide (TMZ) therapy offers minimal clinical benefits in patients with glioblastoma multiforme (GBM) high EGFR activity, underscoring the need for effective combination therapy. Here, we show that tonicity-responsive enhancer binding protein (NFAT5) lysine methylation, is a determinant of TMZ response. Mechanistically, activation induces phosphorylated EZH2 (Ser21) and triggers NFAT5 methylation at K668. Methylation prevents cytoplasm interaction E3 ligase TRAF6, thus blocks...
Occludin plays an important role in maintaining tight junction barrier function many types of epithelia. We previously reported that activation transient receptor potential vanilloid subtype 1 (TRPV1) rabbit submandibular gland promoted salivary secretion, partly by increase paracellular permeability. have now explored the occludin TRPV1-modulated permeability a rat cell line SMG-C6. Both TRPV1 and were expressed SMG-C6 cells, capsaicin induced redistribution occludin, but not claudin-3,...
OBJECTIVE:To clarify the clinical role of contrast enhanced ultrasound (CEUS) in predicting BI-RADS 4 breast disease. METHODS:A total 92 sites diseases were reassessed by routine and CEUS. The main indicators ultrasound, CEUS combination t wo modalities picked up binary logistic regression analysis, scoring 0 for benign 1 malignant characteristics with pathology as referential standard to generate corresponding score systems them. Finally, receiver operating characteristic curves (ROC)...
In this paper, we investigated the dynamics of a bubble rising inside ratchet channels filled with viscoelastic liquids by means volume-of-fluid-based direct numerical simulations. The exponential Phan–Thien–Tanner constitutive model was used to describe rheological behaviors nonlinear fluid. effects fluid elasticity [characterized relaxation time (λ)] and angle (θ) are mainly discussed in respect (e.g., velocity, flow field, stress etc.). Our results found that rise velocity increases...
As China transitions from high-speed to high-quality economic development, the concept of sustainable particularly environmental, social, and governance (ESG), has emerged as a crucial consideration in corporate decision-making. This study examines relationship between ESG performance resilience through lens capital allocation efficiency. Employing fixed-effects model, heterogeneity analysis, mediation effect we analyzed 4436 A-share listed companies that were rated according standards by...
Canonical transient receptor potential-6 (TRPC6) has been reported to be involved in cell damage after ischemia/reperfusion (I/R) injury target organs. While the effect and of TRPC6 on pyroptosis renal I/R remain unclear. In our study, we first established mouse model oxygen–glucose deprivation re-oxygenation (OGD/R) model, investigated impacts pyroptosis-related proteins using CCK-8, western blot, ELISA, immunofluorescence probes. Besides, also explored mechanism tubular epithelial cells...